Plerixafor induces the rapid and transient release of stromal cell-derived factor-1 alpha from human mesenchymal stromal cells and influences the migration behavior of human hematopoietic progenitor cells.

scientific article published on 14 December 2013

Plerixafor induces the rapid and transient release of stromal cell-derived factor-1 alpha from human mesenchymal stromal cells and influences the migration behavior of human hematopoietic progenitor cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00441-013-1759-7
P698PubMed publication ID24337688

P50authorAxel RosenhahnQ39712655
Rainer SaffrichQ54165999
Michael GrunzeQ70856963
P2093author name stringAnthony D Ho
Patrick Wuchter
Volker Eckstein
Maximilian Hanke
Christina Leinweber
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Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonistQ34412254
How do stem cells find their way home?Q34418463
The use of AMD3100 plus G-CSF for autologous hematopoietic progenitor cell mobilization is superior to G-CSF aloneQ34418466
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Microfluidics-based devices: New tools for studying cancer and cancer stem cell migrationQ34856626
The many facets of SDF-1alpha, CXCR4 agonists and antagonists on hematopoietic progenitor cellsQ35804766
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Maintenance of hemopoietic stem cells and production of differentiated progeny in allogeneic and semiallogeneic bone marrow chimeras in vitroQ36335471
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.Q36376700
Can anti-migratory drugs be screened in vitro? A review of 2D and 3D assays for the quantitative analysis of cell migrationQ36556528
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Shear stress regulates adhesion and rolling of CD44+ leukemic and hematopoietic progenitor cells on hyaluronan.Q39497077
Effective ex vivo expansion of hematopoietic stem cells using osteoblast-differentiated mesenchymal stem cells is CXCL12 dependentQ39749989
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Human mesenchymal stromal cells regulate initial self-renewing divisions of hematopoietic progenitor cells by a beta1-integrin-dependent mechanismQ40207371
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Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cellsQ41866922
Appropriate calibration curve fitting in ligand binding assaysQ42565474
Safety and preliminary efficacy of plerixafor (Mozobil) in combination with chemotherapy and G-CSF: an open-label, multicenter, exploratory trial in patients with multiple myeloma and non-Hodgkin's lymphoma undergoing stem cell mobilizationQ42623080
Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells.Q43222889
A combination of granulocyte-colony-stimulating factor (G-CSF) and plerixafor mobilizes more primitive peripheral blood progenitor cells than G-CSF alone: results of a European phase II studyQ43237730
Functional potentials of human hematopoietic progenitor cells are maintained by mesenchymal stromal cells and not impaired by plerixaforQ43530159
Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow.Q45501605
Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placentaQ46531963
On the symmetry of siblings: automated single-cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup.Q50669741
Human AB serum and thrombin-activated platelet-rich plasma are suitable alternatives to fetal calf serum for the expansion of mesenchymal stem cells from adipose tissue.Q50707616
Accelerated and safe expansion of human mesenchymal stromal cells in animal serum-free medium for transplantation and regenerative medicine.Q51018136
Molecular and secretory profiles of human mesenchymal stromal cells and their abilities to maintain primitive hematopoietic progenitors.Q53718332
Characterization of hematopoietic stem cell subsets from patients with multiple myeloma after mobilization with plerixafor.Q54401818
A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrowQ57601743
Adhesion of hematopoietic progenitor cells to human mesenchymal stem cells as a model for cell−cell interactionQ58291579
Processus and recessus adhaerentes: giant adherens cell junction systems connect and attract human mesenchymal stem cellsQ58438325
P433issue2
P304page(s)315-326
P577publication date2013-12-14
P1433published inCell and Tissue ResearchQ1524113
P1476titlePlerixafor induces the rapid and transient release of stromal cell-derived factor-1 alpha from human mesenchymal stromal cells and influences the migration behavior of human hematopoietic progenitor cells.
P478volume355

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cites work (P2860)
Q48138880Dynamic cellular phynotyping defines specific mobilization mechanisms of human hematopoietic stem and progenitor cells induced by SDF1α versus synthetic agents
Q89620663Sitagliptin Stimulates Endothelial Progenitor Cells to Induce Endothelialization in Aneurysm Necks Through the SDF-1/CXCR4/NRF2 Signaling Pathway

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