TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker.

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TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1634/THEONCOLOGIST.2017-0064
P932PMC publication ID5634768
P698PubMed publication ID28754720

P2093author name stringLi Liu
Dawei Xu
Kun Wang
Catharina Larsson
Cheng Liu
Feng Kong
Kexin Wang
Omid Fotouhi
Guangyong Zhang
Sanyuan Hu
Benkang Shi
Yidong Fan
Chuanyou Xia
P2860cites workCancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical ImplicationsQ26738705
Analysis of fecal DNA methylation to detect gastrointestinal neoplasiaQ30491000
TERT promoter mutations in renal cell carcinomas and upper tract urothelial carcinomasQ33688439
Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancerQ34100603
DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNAQ34141525
Regulation of the human catalytic subunit of telomerase (hTERT).Q34180715
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanismsQ34369723
TERT promoter mutations and gene amplification: promoting TERT expression in Merkel cell carcinomaQ34654382
TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCRQ35068013
TERT promoter mutations and TERT mRNA but not FGFR3 mutations are urinary biomarkers in Han Chinese patients with urothelial bladder cancerQ35151119
The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expressionQ35741571
Circulating Tumor Cells, DNA, and mRNA: Potential for Clinical Utility in Patients With Melanoma.Q36452245
Telomerase at the intersection of cancer and agingQ37497995
Prospective evaluation of methylated SEPT9 in plasma for detection of asymptomatic colorectal cancerQ37552649
Telomerase as a "stemness" enzymeQ38211826
The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomasQ39076273
Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cellsQ39263985
Cancer statistics in China, 2015.Q40064386
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start siteQ40185373
DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene.Q40907825
Novel methylation panel for the early detection of colorectal tumors in stool DNA.Q42965516
DNA methylation-based fecal biomarkers for the noninvasive screening of GI cancersQ44108212
Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeresQ44590135
Methylation of the hTERT promoter: a novel cancer biomarker for leptomeningeal metastasis detection in cerebrospinal fluidsQ46577098
Multitarget stool DNA testing for colorectal-cancer screeningQ48331668
Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.Q50859079
Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.Q53387220
Detection of colorectal neoplasm using promoter methylation of ITGA4, SFRP2, and p16 in stool samples: a preliminary report in Korean patientsQ53452931
The absence of TERT promoter mutations in primary gastric cancer.Q54374140
hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia: associations with immunophenotype and cytogenetic subgroup.Q54560829
Analysis of DNA methylation status of the promoter of human telomerase reverse transcriptase in gastric carcinogenesis.Q54677342
Evaluation of telomerase mRNA (hTERT) in colon cancerQ59219407
Relevance of Urine Telomerase in the Diagnosis of Bladder CancerQ59300443
Catalytic Subunit of Human Telomerase Reverse Transcriptase Is an Independent Predictor of Survival in Patients Undergoing Curative Resection of Hepatic Colorectal Metastases: A Multicenter AnalysisQ60629744
Methylation of the human telomerase gene CpG islandQ73453061
Demethylating reagent 5-azacytidine inhibits telomerase activity in human prostate cancer cells through transcriptional repression of hTERTQ74067288
Telomerase activity and the expression of telomerase components in acute myelogenous leukaemiaQ77348257
Expression of the full-length telomerase reverse transcriptase (hTERT) transcript in both malignant and normal gastric tissuesQ79962935
Site-specific methylation of CpG nucleotides in the hTERT promoter region can control the expression of hTERT during malignant progression of colorectal carcinomaQ80730166
CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cellsQ81469389
Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross pathsQ83986260
The diagnostic value of DNA hypermethylation in stool for colorectal cancer: a meta-analysisQ86766263
P433issue10
P921main subjectbiomarkerQ864574
hypermethylationQ106875739
P304page(s)1178-1188
P577publication date2017-07-28
P1433published inOncologistQ2122327
P1476titleTERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker.
P478volume22

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cites work (P2860)
Q91723523Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players
Q98771155Role of DNA Methylation in the Resistance to Therapy in Solid Tumors
Q91716266Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics
Q98158989Telomeres and telomerase in oncogenesis