Neonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4(R24C) C57BL/6 mice.

scientific article

Neonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4(R24C) C57BL/6 mice. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/IJC.25913
P698PubMed publication ID21207411
P5875ResearchGate publication ID49729969

P50authorTobias BaldQ43117864
P2093author name stringThomas Tüting
Jennifer Landsberg
Judith Kohlmeyer
Evelyn Gaffal
Alexander Sporleder
P2860cites workSun exposure and risk of melanomaQ24675559
Mutations of the BRAF gene in human cancerQ27860760
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanomaQ28270834
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanomaQ28296086
ARF functions as a melanoma tumor suppressor by inducing p53-independent senescenceQ28591778
BRAFE600-associated senescence-like cell cycle arrest of human naeviQ29619550
Single UVB overexposure stimulates melanocyte proliferation in murine skin, in contrast to fractionated or UVA-1 exposureQ33210969
Development of a new mouse model (xeroderma pigmentosum a-deficient, stem cell factor-transgenic) of ultraviolet B-induced melanomaQ33222140
Induction of nevi and skin tumors in Ink4a/Arf Xpa knockout mice by neonatal, intermittent, or chronic UVB exposuresQ33235186
The pathogenesis of melanoma induced by ultraviolet radiationQ33603082
Invasive melanoma in Cdk4-targeted miceQ33949342
Geographical variation in the penetrance of CDKN2A mutations for melanomaQ34134115
Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma modelQ34329975
Oncogenic Braf induces melanocyte senescence and melanoma in miceQ34974162
Rapid growth of invasive metastatic melanoma in carcinogen-treated hepatocyte growth factor/scatter factor-transgenic mice carrying an oncogenic CDK4 mutationQ35221992
From UVs to metastases: modeling melanoma initiation and progression in the mouse.Q37267202
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulationQ39654655
Complete regression of advanced primary and metastatic mouse melanomas following combination chemoimmunotherapy.Q39961463
Murine neonatal melanocytes exhibit a heightened proliferative response to ultraviolet radiation and migrate to the epidermal basal layer.Q42439043
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependentQ46068963
Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against authochthonous melanomas in the skin.Q46623134
Building the perfect beast: complex mouse models teach surprisingly simple melanoma lessonsQ47932688
Dual loss of Rb1 and Trp53 in melanocytes perturbs melanocyte homeostasis and genetic stability in vitro but does not cause melanoma or pigmentation defects in vivoQ51799064
Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras miceQ53632288
Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis.Q54655468
Autochthonous primary and metastatic melanomas in Hgf-Cdk4 R24C mice evade T-cell-mediated immune surveillance.Q54661171
The Pathogenesis of Melanoma Induced by Ultraviolet RadiationQ57743135
Neonatal sunburn and melanoma in miceQ59086464
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)285-294
P577publication date2011-04-21
P1433published inInternational Journal of CancerQ332492
P1476titleNeonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4(R24C) C57BL/6 mice.
P478volume129

Reverse relations

cites work (P2860)
Q34674434A melanin-independent interaction between Mc1r and Met signaling pathways is required for HGF-dependent melanoma
Q36796424CDK4: A Key Player in the Cell Cycle, Development, and Cancer
Q26782090Cross-species models of human melanoma
Q40365857Does sunlight protect us from cancer?
Q39329577Genetically engineered mouse models of melanoma
Q57571848Melanoma
Q39090543Mouse models of UV-induced melanoma: genetics, pathology, and clinical relevance.
Q30532511NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma.
Q37687790PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma
Q36711023Phorbol ester-induced neutrophilic inflammatory responses selectively promote metastatic spread of melanoma in a TLR4-dependent manner
Q38254382Photoprotection in changing times - UV filter efficacy and safety, sensitization processes and regulatory aspects
Q41573204The HGF/SF Mouse Model of UV-Induced Melanoma as an In Vivo Sensor for Metastasis-Regulating Gene
Q39016188The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma.
Q46279328Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

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