Antiangiogenic agents and targets: A perspective

scientific article published on October 12, 2010

Antiangiogenic agents and targets: A perspective is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BCP.2010.09.023
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0006295210007215?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0006295210007215?httpAccept=text/xml
P698PubMed publication ID20920481

P2093author name stringBeverly A. Teicher
P2860cites workBIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacyQ27650860
Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinasesQ27657708
Therapeutic antibody targeting of individual Notch receptorsQ27660544
Sorafenib in advanced hepatocellular carcinomaQ27861075
Sunitinib versus interferon alfa in metastatic renal-cell carcinomaQ28282757
Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2Q28570936
Improvement of antiangiogenic cancer therapy by understanding the mechanisms of angiogenic factor interplay and drug resistance.Q37500943
Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way.Q37502702
Drug resistance associated with antiangiogenesis therapyQ37518288
Targeting MET as a strategy to overcome crosstalk-related resistance to EGFR inhibitorsQ37539304
Breast cancer: beyond the cutting edgeQ37598890
Antiangiogenic therapies in breast cancerQ37639970
Impact of anti-angiogenic treatments on metastatic renal cell carcinomaQ37642792
Platelet-derived growth factor receptors regulate mesenchymal stem cell fate: implications for neovascularizationQ37676215
VEGF-A: a critical regulator of blood vessel growthQ37694868
Current status and future prospects for anti-angiogenic therapies in cancer.Q38088366
Hepatocyte growth factor induced up-regulations of VEGF through Egr-1 in hepatocellular carcinoma cellsQ38353151
PlGF blockade does not inhibit angiogenesis during primary tumor growthQ39718360
Placenta growth factor is a survival factor for human malignant mesothelioma cellsQ39841354
CXC-chemokine/CXCR2 biological axis promotes angiogenesis in vitro and in vivo in pancreatic cancerQ39853277
NK4, an HGF antagonist, prevents hematogenous pulmonary metastasis by inhibiting adhesion of CT26 cells to endothelial cellsQ39880907
Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patientsQ39881982
Sunitinib malate (SU-11248) alone or in combination with low-dose docetaxel inhibits the growth of DU-145 prostate cancer xenograftsQ39967256
A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarkerQ40001486
Sorafenib is efficacious and tolerated in combination with cytotoxic or cytostatic agents in preclinical models of human non-small cell lung carcinomaQ40275475
Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumorsQ43054611
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesisQ43072819
Sorafenib in combination with carboplatin and paclitaxel as neoadjuvant chemotherapy in patients with advanced ovarian cancer.Q43142299
Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantatioQ43282877
Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumorsQ44649604
Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myelomaQ46052750
Prospective study of the cutaneous adverse effects of sorafenib, a novel multikinase inhibitorQ46470663
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patientsQ46781791
PlGF expression in pre-invasive and invasive lesions of uterine cervix is associated with angiogenesis and lymphangiogenesis.Q53305472
Protective effect of an inhibitor of interleukin-8 (meraxin) from ischemia and reperfusion injury in a rat model of kidney transplantation.Q53535148
Identification of calreticulin as a prognosis marker and angiogenic regulator in human gastric cancer.Q54504889
Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye DiseaseQ57983635
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growthQ80212331
Placenta growth factor expression has prognostic value in malignant pleural mesotheliomaQ84292418
Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasisQ28593488
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinomaQ30434154
Chemokines as mediators of neovascularizationQ30438032
Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularizationQ33362774
Benefit-risk assessment of sunitinib in gastrointestinal stromal tumours and renal cancerQ33385748
Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistanceQ33627739
Bevacizumab and breast cancer: current therapeutic progress and future perspectivesQ33640753
Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2.Q33710574
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.Q33773569
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesisQ34022315
CXCL12 (SDF-1)/CXCR4 pathway in cancerQ34116260
Small-molecule antagonists for CXCR2 and CXCR1 inhibit human melanoma growth by decreasing tumor cell proliferation, survival, and angiogenesisQ34512415
Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic moleculesQ35684358
The FGF family: biology, pathophysiology and therapyQ36933339
Safety and anti-tumor activity of sorafenib (Nexavar) in combination with other anti-cancer agents: a review of clinical trialsQ37008436
Inflammation, inflammatory cells and angiogenesis: decisions and indecisionsQ37035029
Risk of hand-foot skin reaction with sorafenib: a systematic review and meta-analysisQ37062140
G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse modelsQ37149710
The discovery of the placental growth factor and its role in angiogenesis: a historical reviewQ37196288
Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.Q37234638
Rational targeting of Notch signaling in cancerQ37256451
Notch signaling regulates tumor angiogenesis by diverse mechanismsQ37256455
FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?Q37333639
Biologic therapy of breast cancer: focus on co-inhibition of endocrine and angiogenesis pathwaysQ37356314
Early development of sunitinib in hepatocellular carcinomaQ37357314
Malignant cell-derived PlGF promotes normalization and remodeling of the tumor vasculatureQ37363751
Targeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenograftsQ37364840
Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodiesQ37382152
Positive and negative modulation of angiogenesis by VEGFR1 ligandsQ37401612
Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implicationsQ37410402
Novel therapeutic inhibitors of the c-Met signaling pathway in cancerQ37422804
When the sphingosine kinase 1/sphingosine 1-phosphate pathway meets hypoxia signaling: new targets for cancer therapy.Q37454105
Circulating biomarkers for vascular endothelial growth factor inhibitors in renal cell carcinomaQ37463927
Anticancer strategies involving the vasculatureQ37474318
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectangiogenesis inhibitorQ574834
P304page(s)6-12
P577publication date2010-10-12
P1433published inBiochemical PharmacologyQ864229
P1476titleAntiangiogenic agents and targets: A perspective
P478volume81

Reverse relations

cites work (P2860)
Q34874678Aberrant proliferation in CXCR7+ endothelial cells via degradation of the retinoblastoma protein.
Q38000872Advances in the systemic treatment of cutaneous sarcomas
Q36563542Antiangiogenic therapy for cancer: an update
Q36881812Beyond anti-VEGF: dual-targeting antiangiogenic and antiproliferative therapy
Q51843632Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway.
Q54475869De novo design of N-(pyridin-4-ylmethyl)aniline derivatives as KDR inhibitors: 3D-QSAR, molecular fragment replacement, protein-ligand interaction fingerprint, and ADMET prediction.
Q37604560Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway
Q41062063Endostatin enhances antitumor effect of tumor antigen-pulsed dendritic cell therapy in mouse xenograft model of lung carcinoma
Q37843943Hypoxia-mediated biological control
Q33738607In vivo spectral and fluorescence microscopy comparison of microvascular function after treatment with OXi4503, Sunitinib and their combination in Caki-2 tumors
Q26752752Markers of Response to Antiangiogenic Therapies in Colorectal Cancer: Where Are We Now and What Should Be Next?
Q38025261Modeling and predicting clinical efficacy for drugs targeting the tumor milieu
Q58701885Modulation of the Tumor Microenvironment by CXCR4 Antagonist-Armed Viral Oncotherapy Enhances the Antitumor Efficacy of Dendritic Cell Vaccines against Neuroblastoma in Syngeneic Mice
Q92835893Molecular biomarker-guided anti-angiogenic targeted therapy for malignant glioma
Q36220942Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach
Q35837949Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways
Q37502464Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy
Q33654212Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer
Q34678040Sphingosine‐1‐phosphate antibodies as potential agents in the treatment of cancer and age‐related macular degeneration
Q35122891The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood
Q35067624The intricate role of CXCR4 in cancer
Q36741686c-MET inhibition enhances the response of the colorectal cancer cells to irradiation in vitro and in vivo

Search more.