Association between the germline MC1R variants and somatic BRAF/NRAS mutations in melanoma tumors.

scientific article

Association between the germline MC1R variants and somatic BRAF/NRAS mutations in melanoma tumors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/JID.2010.242
P698PubMed publication ID20720566
P5875ResearchGate publication ID232776606

P50authorDirk SchadendorfQ32649390
Axel HauschildQ32649861
Sabrina AngeliniQ40016284
Rajiv KumarQ42324767
Antje SuckerQ61525189
Kari HemminkiQ63213683
P2093author name stringDominique Scherer
Friederike Egberts
P Sivaramakrishna Rachakonda
Franziska Mehnert
P2860cites workGenetics of Hair and Skin ColorQ28184398
Genetic determinants of hair, eye and skin pigmentation in EuropeansQ28254206
Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissuesQ33272950
MC1R variants increase risk of melanomas harboring BRAF mutations.Q33715143
MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutationsQ34020538
Relationship between germline MC1R variants and BRAF-mutant melanoma in a North Carolina population-based studyQ34179228
New insight into BRAF mutations in cancerQ36701579
Changes in the presentation of nodular and superficial spreading melanomas over 35 yearsQ36759522
BRAF(E600) in benign and malignant human tumoursQ36921234
In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signalingQ40224091
Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populationsQ43776759
The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian populationQ44593803
MC1R germline variants confer risk for BRAF-mutant melanomaQ79815917
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)2844-2848
P577publication date2010-08-19
P1433published inJournal of Investigative DermatologyQ3186921
P1476titleAssociation between the germline MC1R variants and somatic BRAF/NRAS mutations in melanoma tumors.
P478volume130

Reverse relations

cites work (P2860)
Q34674434A melanin-independent interaction between Mc1r and Met signaling pathways is required for HGF-dependent melanoma
Q54441751Assessment of clinical parameters associated with mutational status in metastatic malignant melanoma: a single-centre investigation of 141 patients.
Q40069925Associations of MC1R genotype and patient phenotypes with BRAF and NRAS mutations in melanoma
Q45814416BRAF and MC1R in melanoma: different in head and neck tumors?
Q54310382BRAF, NRAS and MC1R status in a prospective series of primary cutaneous melanoma.
Q50224889Dermoscopic features of cutaneous melanoma are associated with clinical characteristics of patients and tumours and with MC1R genotype.
Q39474116Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors
Q37392769Distribution of MC1R variants among melanoma subtypes: p.R163Q is associated with lentigo maligna melanoma in a Mediterranean population.
Q38646092Melanoma Epidemiology and Prevention
Q36919636Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS
Q57274188NRAS and BRAF Mutations in Cutaneous Melanoma and the Association with MC1R Genotype: Findings from Spanish and Austrian Populations
Q36092451The melanomas: a synthesis of epidemiological, clinical, histopathological, genetic, and biological aspects, supporting distinct subtypes, causal pathways, and cells of origin

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