scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.MOLCEL.2010.06.026 |
P8608 | Fatcat ID | release_lvyiwzohozcqjhevj3he253x5m |
P698 | PubMed publication ID | 20598602 |
P5875 | ResearchGate publication ID | 45089740 |
P50 | author | Jordan D Ward | Q42881166 |
Spencer J. Collis | Q55303040 | ||
Zuzana Hořejší | Q56513640 | ||
Nicola Silva | Q57341411 | ||
Adele Adamo | Q89047129 | ||
P2093 | author name string | Carrie A Adelman | |
Simon J Boulton | |||
Enrique Martinez-Perez | |||
Adriana La Volpe | |||
P433 | issue | 1 | |
P304 | page(s) | 25-35 | |
P577 | publication date | 2010-07-01 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. | |
P478 | volume | 39 |
Q33618910 | "Back to a false normality": new intriguing mechanisms of resistance to PARP inhibitors |
Q39162136 | 5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair |
Q24306275 | A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling |
Q38018068 | A DOG's View of Fanconi Anemia: Insights from C. elegans |
Q35326686 | A PHF8 homolog in C. elegans promotes DNA repair via homologous recombination. |
Q64389478 | A Role in Apoptosis Regulation for the Gene of |
Q33698648 | A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy |
Q41554810 | A novel function for BRCA1 in crosslink repair. |
Q60917718 | ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks |
Q38917809 | Acquisition of Relative Interstrand Crosslinker Resistance and PARP Inhibitor Sensitivity in Fanconi Anemia Head and Neck Cancers |
Q47383621 | Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner |
Q50093546 | Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. |
Q49911835 | Arabidopsis thaliana FANCD2 Promotes Meiotic Crossover Formation. |
Q24338366 | BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks |
Q36174109 | BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells |
Q35923364 | BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair |
Q38753157 | Biallelic inactivation of REV7 is associated with Fanconi anemia |
Q43925901 | Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors. |
Q34337102 | C. elegans ring finger protein RNF-113 is involved in interstrand DNA crosslink repair and interacts with a RAD51C homolog. |
Q34350141 | C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency |
Q27324477 | COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining |
Q58054240 | CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway |
Q99605757 | Canonical and Noncanonical Roles of Fanconi Anemia Proteins: Implications in Cancer Predisposition |
Q33755415 | Cellular Repair of DNA-DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane |
Q26752319 | Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway |
Q90461528 | Changes in DNA Damage Response Markers with Treatment in Advanced Ovarian Cancer |
Q35029335 | Choosing the right path: does DNA-PK help make the decision? |
Q35893816 | Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks |
Q38552583 | Chromosomal Rearrangements in Cancer: Detection and potential causal mechanisms |
Q38042854 | Chromothripsis and cancer: causes and consequences of chromosome shattering |
Q42210707 | Co-opting the Fanconi anemia genomic stability pathway enables herpesvirus DNA synthesis and productive growth |
Q37638191 | Collaboration and competition between DNA double‐strand break repair pathways |
Q34825234 | Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair |
Q35054036 | Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal |
Q38981181 | Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses |
Q36314320 | DEK is required for homologous recombination repair of DNA breaks |
Q35550622 | DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining |
Q34396087 | DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes. |
Q26996175 | DNA double-strand break repair pathway choice and cancer |
Q24305549 | DNA end resection by CtIP and exonuclease 1 prevents genomic instability |
Q35961508 | DNA helicases involved in DNA repair and their roles in cancer |
Q36576047 | DNA interstrand crosslink repair and cancer |
Q38061847 | DNA repair dysregulation from cancer driver to therapeutic target |
Q35531287 | DNA repair mechanisms in cancer development and therapy |
Q37505517 | DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment |
Q36426500 | DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network |
Q84617107 | Dangerous Liaisons: Fanconi Anemia and Toxic Nonhomologous End Joining in DNA Crosslink Repair |
Q38685731 | Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement |
Q38454309 | Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling. |
Q35211147 | Destroying the ring: Freeing DNA from Ku with ubiquitin |
Q38083939 | Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining |
Q49549364 | Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair. |
Q38113932 | End-joining, translocations and cancer |
Q36238650 | Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53 |
Q51045691 | Enhanced non-homologous end joining contributes toward synthetic lethality of pathological RAD51C mutants with poly (ADP-ribose) polymerase. |
Q28749668 | Expanded roles of the Fanconi anemia pathway in preserving genomic stability |
Q36338599 | FANCA safeguards interphase and mitosis during hematopoiesis in vivo. |
Q91996366 | FANCD2 Binding to H4K20me2 via a Methyl-Binding Domain Is Essential for Efficient DNA Cross-Link Repair |
Q33703002 | Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells. |
Q52626888 | Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 Are Required for Maintaining Histone Methylation Levels and Interact with the Histone Demethylase LSD1/SPR-5 in Caenorhabditis elegans. |
Q49616542 | Fanconi anaemia and cancer: an intricate relationship. |
Q28283549 | Fanconi anaemia and the repair of Watson and Crick DNA crosslinks |
Q27014905 | Fanconi anemia and the cell cycle: new perspectives on aneuploidy |
Q36073848 | Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process |
Q90448480 | Fanconi anemia pathway as a prospective target for cancer intervention |
Q37844463 | Fanconi anemia: a disorder defective in the DNA damage response |
Q53707073 | Fork Protection and Therapy Resistance in Hereditary Breast Cancer. |
Q103826094 | Functional characterization of Caenorhabditis elegans cbs-2 gene during meiosis |
Q38960289 | Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage |
Q39154178 | Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells. |
Q87982824 | Genotoxicity of tetrahydrofolic acid to hematopoietic stem and progenitor cells |
Q38554935 | HSV-I and the cellular DNA damage response. |
Q37785490 | Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes |
Q35607367 | Having a direct look: analysis of DNA damage and repair mechanisms by next generation sequencing |
Q64111167 | Holding All the Cards-How Fanconi Anemia Proteins Deal with Replication Stress and Preserve Genomic Stability |
Q35741074 | Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication |
Q38761267 | Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair |
Q36621346 | Hyper-active non-homologous end joining selects for synthetic lethality resistant and pathological Fanconi anemia hematopoietic stem and progenitor cells |
Q24306091 | Identification of the MMS22L-TONSL complex that promotes homologous recombination |
Q42544619 | Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells |
Q92527704 | In vivo analysis of FANCD2 recruitment at meiotic DNA breaks in Caenorhabditis elegans |
Q93041116 | Inactivation of the NHEJ Activity of DNA-PKcs Prevents Fanconi Anemia Pre-Leukemic HSC Expansion |
Q93078920 | Increased Non-Homologous End Joining Makes DNA-PK a Promising Target for Therapeutic Intervention in Uveal Melanoma |
Q47138752 | Increased single-strand annealing rather than non-homologous end-joining predicts hereditary ovarian carcinoma |
Q49833942 | Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks. |
Q28513559 | Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis |
Q34211299 | Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2 |
Q37513959 | LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining |
Q52659709 | Lipidomic profiling links the Fanconi anemia pathway to glycosphingolipid metabolism in head and neck cancer cells. |
Q36706220 | Loss of Fancc Impairs Antibody-Secreting Cell Differentiation in Mice through Deregulating the Wnt Signaling Pathway. |
Q39761629 | Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage |
Q50020640 | Maintenance of Genome Integrity by Mi2 Homologs CHD-3 and LET-418 in Caenorhabditis elegans. |
Q37658498 | Maintenance of genome stability by Fanconi anemia proteins |
Q39293345 | Mechanisms of DNA damage, repair, and mutagenesis |
Q38676330 | Meiosis. |
Q38000414 | Meiotic double strand breaks repair in sexually reproducing eukaryotes: we are not all equal |
Q41817967 | Methodological considerations for mutagen exposure in C. elegans |
Q28085603 | Molding BRCA2 function through its interacting partners |
Q24621696 | Molecular pathogenesis and clinical management of Fanconi anemia |
Q39553171 | Monoubiquitinated Fanconi anemia D2 (FANCD2-Ub) is required for BCR-ABL1 kinase-induced leukemogenesis |
Q34602683 | Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells. |
Q34819388 | Papillomaviruses use recombination-dependent replication to vegetatively amplify their genomes in differentiated cells |
Q35814233 | Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis |
Q39015856 | Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells |
Q37090144 | Pro-crossover factors regulate damage-dependent apoptosis in the Caenorhabditis elegans germ line |
Q38738716 | Protection or resection: BOD1L as a novel replication fork protection factor |
Q64389208 | Rad51 recruitment and exclusion of non-homologous end joining during homologous recombination at a Tus/Ter mammalian replication fork barrier |
Q35050871 | Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair |
Q38985539 | Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia |
Q37589103 | Recent insights into inherited bone marrow failure syndromes |
Q39385071 | Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers |
Q39210775 | Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in uveal melanoma and Fanconi anaemia |
Q49166715 | Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia. |
Q42368008 | Redundancy between nucleases required for homologous recombination promotes PARP inhibitor resistance in the eukaryotic model organism Dictyostelium. |
Q60216914 | Refinement of high-risk endometrial cancer classification using DNA damage response biomarkers: a TransPORTEC initiative |
Q34285356 | Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway |
Q38906341 | Regulation of Single-Strand Annealing and its Role in Genome Maintenance |
Q38559892 | Regulation of recombination and genomic maintenance |
Q37682205 | Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor |
Q28478289 | Repair at single targeted DNA double-strand breaks in pluripotent and differentiated human cells |
Q34473453 | Replication stress and cancer |
Q28087011 | Replication stress in Mammalian cells and its consequences for mitosis |
Q35678377 | Rescue of replication failure by Fanconi anaemia proteins |
Q47549712 | Risk of Human Papillomavirus Infection in Cancer-Prone Individuals: What We Know |
Q92196141 | SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability |
Q99632197 | Suppression of non-homologous end joining does not rescue DNA repair defects in Fanconi anemia patient cells |
Q93216832 | TALEN mediated gene editing in a mouse model of Fanconi anemia |
Q36880474 | TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia. |
Q34034240 | TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer |
Q35676920 | Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors |
Q37452985 | Targeting an Achilles' heel of cancer with a WRN helicase inhibitor |
Q34718519 | The 53BP1 homolog in C. elegans influences DNA repair and promotes apoptosis in response to ionizing radiation |
Q37064133 | The BLM dissolvasome in DNA replication and repair. |
Q34787446 | The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection |
Q64069350 | The DNA Alkylguanine DNA Alkyltransferase-2 (AGT-2) Of Caenorhabditis Elegans Is Involved In Meiosis And Early Development Under Physiological Conditions |
Q27861055 | The DNA Damage Response: Making It Safe to Play with Knives |
Q48117756 | The Exonuclease Homolog OsRAD1 Promotes Accurate Meiotic Double-Strand Break Repair by Suppressing Nonhomologous End Joining. |
Q38825562 | The Fanconi anaemia pathway: new players and new functions |
Q30994273 | The Fanconi anemia core complex is dispensable during somatic hypermutation and class switch recombination. |
Q37526483 | The MRE11 complex: starting from the ends. |
Q34359422 | The Mph1 helicase can promote telomere uncapping and premature senescence in budding yeast |
Q37397475 | The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair |
Q38690281 | The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer |
Q39560571 | The USP1/UAF1 complex promotes double-strand break repair through homologous recombination |
Q38037329 | The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance |
Q64105526 | The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance |
Q27727978 | The role of ADP-ribosylation in regulating DNA interstrand crosslink repair |
Q38063711 | The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability |
Q35807522 | Transgene-mediated cosuppression and RNA interference enhance germ-line apoptosis in Caenorhabditis elegans. |
Q39312769 | UNC-84: "LINC-ing" chromosome movement and double strand break repair. |
Q42729257 | USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation. |
Q38923383 | Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage |
Q40603571 | Unraveling the complexities of DNA-dependent protein kinase autophosphorylation |
Q42363974 | V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca(-/-) mice |
Q64067901 | WIP1 Contributes to the Adaptation of Fanconi Anemia Cells to DNA Damage as Determined by the Regulatory Network of the Fanconi Anemia and Checkpoint Recovery Pathways |
Q37154365 | Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway |
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