High Prognostic Value of p16INK4 Alterations in Gastrointestinal Stromal Tumors

scientific article published on May 1, 2003

High Prognostic Value of p16INK4 Alterations in Gastrointestinal Stromal Tumors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1200/JCO.2003.08.101
P953full work available at URLhttps://ascopubs.org/doi/pdfdirect/10.1200/JCO.2003.08.101
P698PubMed publication ID12721243

P50authorMarkku MiettinenQ55221582
Jerzy LasotaQ106621949
P2093author name stringThomas Günther
Albert Roessner
Brigitte Peters
Regine Schneider-Stock
Matthias Pross
Carsten Boltze
P2860cites workMethylation-specific PCR: a novel PCR assay for methylation status of CpG islandsQ24631957
KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in sizeQ27824783
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumorsQ28118852
The INK4a/ARF network in tumour suppressionQ28190064
A cell cycle regulator potentially involved in genesis of many tumor typesQ28251933
Gastrointestinal stromal tumors--definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosisQ32049769
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumoursQ34465751
Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a reviewQ34718294
Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 casesQ35745870
Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomasQ35754637
KIT extracellular and kinase domain mutations in gastrointestinal stromal tumorsQ35809846
Mutations and altered expression of p16INK4 in human cancer.Q35892778
Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancerQ40822748
Loss of heterozygosity on chromosome 9q21 (p16 gene) uncommon in soft-tissue sarcomasQ41130523
The tumor suppressor protein p16INK4a.Q41673713
Alterations in the p16INK4a/CDKN2A tumor suppressor gene in gastrinomasQ42496499
Early acquisition of homozygous deletions of p16/p19 during squamous cell carcinogenesis and genetic mosaicism in bladder cancerQ44242248
Chromosomal aberrations in malignant gastrointestinal stromal tumors: correlation with c-KIT gene mutationQ49222497
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancersQ55480673
K-ras and p16 aberrations confer poor prognosis in human colorectal cancerQ57240056
Methylation of p16INK4A in primary gynecologic malignancyQ63641154
Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT)Q73117142
Putative chromosomal deletions on 9P, 9Q and 22Q occur preferentially in malignant gastrointestinal stromal tumorsQ73504383
Predicting Metastatic Risk of Gastrointestinal Stromal Tumors: Role of Cell Proliferation and Cell Cycle Regulatory ProteinsQ74332318
Diagnosis of gastrointestinal stromal tumors: A consensus approachQ74400164
Telomerase activity in gastrointestinal stromal tumorsQ77596968
Biological and clinical significance of cytogenetic abnormalities in low-risk and high-risk gastrointestinal stromal tumorsQ78016289
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectoncologyQ162555
DNA methylationQ874745
cancer stagingQ1752284
CDKN2AQ5009957
P304page(s)1688-1697
P577publication date2003-05-01
P1433published inJournal of Clinical OncologyQ400292
P1476titleHigh Prognostic Value of p16INK4 Alterations in Gastrointestinal Stromal Tumors
P478volume21

Reverse relations

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