LRRK2 G2019S and R1441G mutations associated with Parkinson's disease are common in the Basque Country, but relative prevalence is determined by ethnicity.

scientific article

LRRK2 G2019S and R1441G mutations associated with Parkinson's disease are common in the Basque Country, but relative prevalence is determined by ethnicity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10048-008-0162-0
P698PubMed publication ID19020907
P5875ResearchGate publication ID225227769

P50authorJosé Félix Martí MassóQ59546069
Adolfo López de MunainQ64780336
P2093author name stringA Gorostidi
J Ruiz-Martínez
A Alzualde
P2860cites workCloning of the gene containing mutations that cause PARK8-linked Parkinson's diseaseQ28292932
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control studyQ29614953
Diagnostic criteria for Parkinson diseaseQ34489839
G2019S LRRK2 mutation in French and North African families with Parkinson's diseaseQ39171895
High prevalence of LRRK2 mutations in familial and sporadic Parkinson's disease in PortugalQ45281911
Is the G2019S LRRK2 mutation common in all southern European populations?Q46948308
LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetranceQ46988538
A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease.Q54683068
Lrrk2-associated parkinsonism is a major cause of disease in Northern SpainQ57983267
LRRK2 mutations are a common cause of Parkinson's disease in SpainQ57983278
A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's diseaseQ58870346
Parkinson's disease due to the R1441G mutation in Dardarin: a founder effect in the BasquesQ80314487
P433issue2
P921main subjectParkinson's diseaseQ11085
P304page(s)157-159
P577publication date2008-11-20
P1433published inNeurogeneticsQ15710048
P1476titleLRRK2 G2019S and R1441G mutations associated with Parkinson's disease are common in the Basque Country, but relative prevalence is determined by ethnicity
P478volume10

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cites work (P2860)
Q61805965A Comprehensive Analysis of Population Differences in Variant Distribution in Parkinson's Disease
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Q38433725Cellular processes associated with LRRK2 function and dysfunction
Q22252904Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update
Q38164890Genetic testing of LRRK2 in Parkinson's disease: is there a clinical role?
Q26827825Genetics of Parkinson's disease
Q44199951High frequency and reduced penetrance of lRRK2 g2019S mutation among Parkinson's disease patients in Cantabria (Spain)
Q36477677Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity
Q55410950LRRK 2 gene mutations in the pathophysiology of the ROCO domain and therapeutic targets for Parkinson's disease: a review.
Q42927984LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity
Q47718405LRRK2 gene variation and its contribution to Parkinson disease
Q53209404LRRK2 haplotype-sharing analysis in Parkinson's disease reveals a novel p.S1761R mutation
Q92933189LRRK2 in Parkinson disease: challenges of clinical trials
Q37608624LRRK2 in Parkinson's disease: genetic and clinical studies from patients
Q37635000LRRK2: Cause, Risk, and Mechanism
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Q54978235Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo.
Q38273952Neurogenetic disorders in the Basque population
Q46521682Olfactory deficits and cardiac 123I-MIBG in Parkinson's disease related to the LRRK2 R1441G and G2019S mutations
Q44350484Prevalence of cancer in Parkinson's disease related to R1441G and G2019S mutations in LRRK2.
Q34121655Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2
Q37597933The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews
Q55265334The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.
Q40783163The discovery of LRRK2 p.R1441S, a novel mutation for Parkinson's disease, adds to the complexity of a mutational hotspot
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Q33767528Variable frequency of LRRK2 variants in the Latin American research consortium on the genetics of Parkinson's disease (LARGE-PD), a case of ancestry.
Q34540556Αlpha-synuclein levels in blood plasma from LRRK2 mutation carriers

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