S1P₄ Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells.

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S1P₄ Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells. is …
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scholarly articleQ13442814

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P356DOI10.3390/IJMS19051279
P8608Fatcat IDrelease_h25rcyxt5zg4bhtkuxebdanmbi
P932PMC publication ID5983835
P698PubMed publication ID29693558

P50authorElisabeth M LarsonQ60330084
Dean D. MetcalfeQ90856971
P2093author name stringRichard L Proia
Ana Olivera
Joseph M Kulinski
P2860cites workEDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissueQ22004152
Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactionsQ24310253
Role of ABCC1 in export of sphingosine-1-phosphate from mast cellsQ24671687
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Developmental origin and functional specialization of mast cell subsetsQ27012213
Early signaling pathways activated by c-Kit in hematopoietic cellsQ28139288
Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6Q28141106
The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13Q28205972
Mast cellsQ28253429
IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responsesQ28586614
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits.Q30354462
Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edemaQ33730147
Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.Q33815638
Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cellsQ34011657
Extracellular and Intracellular Actions of Sphingosine-1-PhosphateQ34183703
Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functionsQ34272235
Measuring Mast Cell Mediator ReleaseQ34313871
Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cellsQ34442444
Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.Q34606305
Anaphylaxis: lessons from mouse modelsQ34674225
Rapid polyclonal desensitization with antibodies to IgE and FcεRIαQ35125056
G protein coupled receptor specificity for C3a and compound 48/80-induced degranulation in human mast cells: roles of Mas-related genes MrgX1 and MrgX2.Q35202333
The ins and outs of IgE-dependent mast-cell exocytosisQ35751914
Normal and oncogenic forms of the receptor tyrosine kinase kit.Q35996350
Regulation of mast cell responses in health and diseaseQ36092456
Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell functionQ36240870
Shaping the landscape: metabolic regulation of S1P gradientsQ36356934
Droplet Digital PCR versus qPCR for gene expression analysis with low abundant targets: from variable nonsense to publication quality dataQ36382174
Integrated signalling pathways for mast-cell activationQ36392833
IL-33 fine tunes mast cell degranulation and chemokine production at the single-cell level.Q51051066
Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes.Q53140769
Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterizationQ61140921
The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxisQ79905421
Sphingosine-1-phospate receptor 4 (S1P₄) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine modelQ84719235
Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodesQ87388394
Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxisQ36399383
Interrogation of sphingosine-1-phosphate receptor 2 function in vivo reveals a prominent role in the recovery from IgE and IgG-mediated anaphylaxis with minimal effect on its onsetQ36698606
Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33.Q36744984
Apoptotic tumor cells induce IL-27 release from human DCs to activate Treg cells that express CD69 and attenuate cytotoxicityQ36922033
Mast cells: versatile regulators of inflammation, tissue remodeling, host defense and homeostasis.Q37006897
The alliance of sphingosine-1-phosphate and its receptors in immunityQ37010807
Amplification mechanisms for the enhancement of antigen-mediated mast cell activationQ37259631
Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiationQ37411248
The mast cell: an evolutionary perspectiveQ37644527
Advances in mast cell biology: new understanding of heterogeneity and functionQ37665290
Mast cells and immunoregulation/immunomodulation.Q37895548
Sphingosine-1-phosphate and lymphocyte egress from lymphoid organsQ37965743
IgE and mast cells in allergic diseaseQ38007829
Beyond Immune Cell Migration: The Emerging Role of the Sphingosine-1-phosphate Receptor S1PR4 as a Modulator of Innate Immune Cell ActivationQ38605015
Interleukin-33 in health and diseaseQ38957840
Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis.Q39010581
TGFβ1 evokes myoblast apoptotic response via a novel signaling pathway involving S1P4 transactivation upstream of Rho-kinase-2 activation.Q39115522
Generation, isolation, and maintenance of rodent mast cells and mast cell linesQ39988963
Involvement of sphingosine 1-phosphate (S1P) receptor type 1 and type 4 in migratory response of mouse T cells toward S1P.Q40178407
Peptidergic pathway in human skin and rat peritoneal mast cell activation.Q40389869
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxisQ40777268
Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesisQ40914150
Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.Q41577951
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.Q42507660
IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cellsQ42736146
Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cellsQ44951894
Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice.Q45011745
Type 4 sphingosine 1-phosphate G protein-coupled receptor (S1P4) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migrationQ46620860
S1P Signalling Differentially Affects Migration of Peritoneal B Cell Populations In Vitro and Influences the Production of Intestinal IgA In Vivo.Q48140617
S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells.Q48259591
Mast Cells Signal their Importance in Health and DiseaseQ49896196
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmast cellQ191989
anaphylactic shockQ15965523
anaphylaxisQ168800
P577publication date2018-04-25
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleS1P₄ Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells.
P478volume19

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cites work (P2860)
Q91963590Aldh2 Attenuates Stem Cell Factor/Kit-Dependent Signaling and Activation in Mast Cells
Q57471234The Enigma of Sphingolipids in Health and Disease

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