Spontaneous mutations in CYC8 and MIG1 suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK.

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Spontaneous mutations in CYC8 and MIG1 suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15698/MIC2018.05.630
P932PMC publication ID5961917
P698PubMed publication ID29796388

P2093author name stringJeffrey S Smith
Mingguang Li
Nazif Maqani
Elisa Enriquez-Hesles
Mehreen Shahid
Ryan D Fine
P2860cites workGenes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiaeQ24531149
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ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein KinaseQ27675159
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Dual influence of the yeast Cat1p (Snf1p) protein kinase on carbon source-dependent transcriptional activation of gluconeogenic genes by the regulatory gene CAT8.Q27930961
Regulation of Snf1 kinase. Activation requires phosphorylation of threonine 210 by an upstream kinase as well as a distinct step mediated by the Snf4 subunitQ27931918
Two homologous zinc finger genes identified by multicopy suppression in a SNF1 protein kinase mutant of Saccharomyces cerevisiaeQ27932496
Regulated nuclear translocation of the Mig1 glucose repressorQ27933224
SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase IIQ27933314
Glucose derepression of gluconeogenic enzymes in Saccharomyces cerevisiae correlates with phosphorylation of the gene activator Cat8pQ27933533
The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiaeQ27933847
Cti6, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1.Q27934762
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Molecular genetic analysis of the yeast repressor Rfx1/Crt1 reveals a novel two-step regulatory mechanismQ27936066
Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo.Q27936729
The Snf1 kinase and proteasome-associated Rad23 regulate UV-responsive gene expressionQ27936856
The yeast AMPK homolog SNF1 regulates acetyl coenzyme A homeostasis and histone acetylationQ37336113
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The Snf1 kinase controls glucose repression in yeast by modulating interactions between the Mig1 repressor and the Cyc8-Tup1 co-repressorQ40101007
Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.Q40398133
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Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentrationQ41897937
The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prionQ41980656
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Ethanol and acetate acting as carbon/energy sources negatively affect yeast chronological agingQ42591777
The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesisQ43092036
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Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promotersQ72130901
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Comparison of methods used for assessing the viability and vitality of yeast cellsQ87653295
CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiaeQ27937168
Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stressQ27938913
The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE)Q27940320
Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applicationsQ28131600
The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and AgingQ28276378
Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitroQ28278317
TPR proteins: the versatile helixQ29547585
Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteinsQ29622934
Caloric restriction extends yeast chronological lifespan by optimizing the Snf1 (AMPK) signaling pathwayQ30252733
Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populationsQ30300373
AMPK in Yeast: The SNF1 (Sucrose Non-fermenting 1) Protein Kinase ComplexQ30394876
A microarray-based genetic screen for yeast chronological aging factorsQ30436367
Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the SirtuinsQ30444310
Combinatorial control of gene expression by the three yeast repressors Mig1, Mig2 and Mig3Q33393390
Glucose repression in yeastQ33632468
Snf1 protein kinase regulates phosphorylation of the Mig1 repressor in Saccharomyces cerevisiaeQ33781305
A suppressor of SNF1 mutations causes constitutive high-level invertase synthesis in yeastQ33950088
Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activityQ34093803
YeastMine--an integrated data warehouse for Saccharomyces cerevisiae data as a multipurpose tool-kit.Q34204366
"Sleeping beauty": quiescence in Saccharomyces cerevisiaeQ34348944
Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescenceQ34361242
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiaeQ34548962
AMPK at the nexus of energetics and aging.Q34871517
Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repressionQ34951810
Isolation of mutations in the catalytic domain of the snf1 kinase that render its activity independent of the snf4 subunitQ34993926
The chronological life span of Saccharomyces cerevisiaeQ35185540
The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting proteinQ35624743
Access denied: Snf1 activation loop phosphorylation is controlled by availability of the phosphorylated threonine 210 to the PP1 phosphataseQ35630441
Variable Glutamine-Rich Repeats Modulate Transcription Factor ActivityQ35976012
Cross-Talk between Carbon Metabolism and the DNA Damage Response in S. cerevisiaeQ36090408
Chronological Lifespan in Yeast Is Dependent on the Accumulation of Storage Carbohydrates Mediated by Yak1, Mck1 and Rim15 Kinases.Q36214280
Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiaeQ36321871
Transcriptional repression by Tup1-Ssn6.Q36579338
Program-like aging and mitochondria: instead of random damage by free radicalsQ36988252
P4510describes a project that usesedgeRQ113334690
P433issue5
P921main subjectlifetimeQ22675021
P304page(s)233-248
P577publication date2018-02-19
P1433published inMicrobial cell (Graz, Austria)Q56298176
P1476titleSpontaneous mutations in CYC8 and MIG1 suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK.
P478volume5

Reverse relations

Q64916439Conventional and emerging roles of the energy sensor Snf1/AMPK in Saccharomyces cerevisiae.cites workP2860