Knockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest.

scientific article

Knockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1104137893
P356DOI10.1186/S12931-018-0804-1
P932PMC publication ID5963077
P698PubMed publication ID29784046

P2093author name stringJing Li
Jian Zhou
Jie Hu
Chunxue Bai
Tao Fang
Meijia Chang
P2860cites workControl of apoptosis and mitotic spindle checkpoint by survivinQ22008570
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinibQ24561953
Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repairQ27667441
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signalingQ27851406
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trialQ27851712
Annexin V inhibits the 12-O-tetradecanoylphorbol-13-acetate-induced activation of Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of Shc in MCF-7 cells.Q53408513
Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort.Q54340897
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M.Q27853162
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathwaysQ28274882
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFRQ29547545
The quest to overcome resistance to EGFR-targeted therapies in cancerQ33725976
Escape of U251 glioma cells from temozolomide-induced senescence was modulated by CDK1/survivin signalingQ33733121
Identification of molecular target proteins in berberine-treated cervix adenocarcinoma HeLa cells by proteomic and bioinformatic analysesQ34239927
Advances on EGFR mutation for lung cancerQ35200375
Annexin-A5 promotes membrane resealing in human trophoblasts.Q35543998
The role of annexin A5 in the modulation of the immune response against dying and dead cellsQ36737880
Nuclear mode of the EGFR signaling network: biology, prognostic value, and therapeutic implicationsQ36798851
Annexin A5: shifting from a diagnostic towards a therapeutic realmQ36944759
Physical Proximity of Sister Chromatids Promotes Top2-Dependent IntertwiningQ37341759
Annexin A5 as a potential marker in tumorsQ38152191
Acquired resistance to TKIs in solid tumours: learning from lung cancerQ38224967
Review: Annexin-A5 and cell membrane repair.Q38363318
High Annexin A5 expression promotes tumor progression and poor prognosis in renal cell carcinomaQ38708346
A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.Q38720703
Anxa5 mediates the in vitro malignant behaviours of murine hepatocarcinoma Hca-F cells with high lymph node metastasis potential preferentially via ERK2/p-ERK2/c-Jun/p-c-Jun(Ser73) and E-cadherinQ38742701
Topoisomerase II Inhibitors and Poisons, and the Influence of Cell Cycle CheckpointsQ39029651
The molecular mechanisms of chemoresistance in cancersQ41709101
The G2 checkpoint-a node-based molecular switchQ42231430
ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinaseQ44082647
PLK1 Activation in Late G2 Sets Up Commitment to MitosisQ47316004
Expression of annexin a5 is associated with higher tumor stage and poor prognosis in colorectal adenocarcinomasQ47746860
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue1
P304page(s)96
P577publication date2018-05-21
P1433published inRespiratory ResearchQ7315904
P1476titleKnockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest.
P478volume19

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cites work (P2860)
Q58802947Calpain 2 knockdown promotes cell apoptosis and restores gefitinib sensitivity through epidermal growth factor receptor/protein kinase B/survivin signaling
Q90699297Discovery of potential targets of Triptolide through inverse docking in ovarian cancer cells

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