Point mutations of ras and Gs alpha subunit genes in thyroid tumors.

scientific article published in August 1995

Point mutations of ras and Gs alpha subunit genes in thyroid tumors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1349-7006.1995.TB02462.X
P932PMC publication ID5920910
P698PubMed publication ID7559096
P5875ResearchGate publication ID229501494

P2093author name stringH Horie
S Saito
M Tsuyuguchi
Y Yokogoshi
P2860cites workTwo G protein oncogenes in human endocrine tumorsQ28301270
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Clonal composition of benign and malignant human thyroid tumorsQ34255486
Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cellsQ34340548
Genetic basis of endocrine disease 3: Molecular defects in thyroid gland neoplasiaQ35596740
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomasQ35823973
Signal transduction via the MAP kinases: proceed at your own RSK.Q36381460
Activation of the cyclic AMP cascade as an oncogenic mechanism: the thyroid exampleQ37178964
Evidence for and possible mechanisms of non-genotoxic carcinogenesis in the rodent thyroidQ37751639
Oncogenes and growth factors in thyroid carcinogenesis.Q37901169
Medullary carcinoma of the thyroid gland. Clinical, pathological, and immunohistochemical features with review of the literature.Q38159580
The G-protein family and their interaction with receptorsQ38287157
The thyrotropin receptor (TSH-R) is not an oncogene for thyroid tumors: structural studies of the TSH-R and the alpha-subunit of Gs in human thyroid neoplasmsQ38318649
gsp mutations in human thyroid tumoursQ38335860
Activating point mutations of the gsp oncogene in human thyroid adenomasQ38337366
The molecular biology of medullary thyroid carcinoma. A model for cancer development and progressionQ38626994
Nodular thyroid disease. Evaluation and managementQ39825459
Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.Q41019851
Presence of mutations in all three ras genes in human thyroid tumorsQ41203275
Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.Q41461969
Low frequency of ras gene mutations in neuroblastomas, pheochromocytomas, and medullary thyroid cancersQ41691073
C-myc, N-myc, N-ras, and c-erb-B: lack of amplification or rearrangement in human medullary thyroid carcinoma and a derivative cell line.Q41752179
A pituitary specific point mutation of codon 201 of the Gs alpha gene in a pituitary adenoma of a patient with multiple endocrine neoplasia (MEN) type 1Q42149768
Detection of the H-RAS oncogene in human thyroid anaplastic carcinomasQ42798928
The frequency of cold thyroid nodules and thyroid malignancies in patients from an iodine-deficient areaQ45092459
Mutational activation of RAS and GSP oncogenes in differentiated thyroid cancer and their biological implicationsQ46364978
High rates of ras codon 61 mutation in thyroid tumors in an iodide-deficient area.Q53498540
Inactivation of the p53 gene is not required for tumorigenesis of medullary thyroid carcinoma or pheochromocytomaQ55024513
ras mutations in endocrine tumors: mutation detection by polymerase chain reaction-single strand conformation polymorphismQ55417795
A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinomaQ55670928
Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTCQ57591365
Hyperthyroidism and thyroid cancerQ67928062
Ras oncogene mutations in benign and malignant thyroid neoplasmsQ67970594
High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinomaQ69398273
High frequency of ras oncogene activation in all stages of human thyroid tumorigenesisQ69490865
Thyroid carcinoma after exposure to atomic radiation. A continuing survey of a fixed population, Hiroshima and Nagasaki, 1958-1971Q69754723
Analysis of the Gs alpha gene in growth hormone-secreting pituitary adenomas by the polymerase chain reaction-direct sequencing method using paraffin-embedded tissuesQ72598967
Rare mutations of the Gs alpha subunit gene in human endocrine tumors. Mutation detection by polymerase chain reaction-primer-introduced restriction analysisQ72851763
Gross and microscopic findings in clinically normal thyroid glandsQ73826422
P433issue8
P1104number of pages6
P304page(s)737-742
P577publication date1995-08-01
P1433published inJapanese Journal of Cancer ResearchQ26842384
P1476titlePoint mutations of ras and Gs alpha subunit genes in thyroid tumors.
P478volume86

Reverse relations

cites work (P2860)
Q41388828Molecular insights into TSH receptor abnormality and thyroid disease
Q53924472Neoplastic non-papillary thyroid carcinoma lesions with a fine chromatin pattern.
Q74023992Non-hyperfunctioning nodules from multinodular goiters: a minor role in pathogenesis for somatic activating mutations in the TSH-receptor and Gsalpha subunit genes
Q26796901RAS proto-oncogene in medullary thyroid carcinoma
Q62930171Role of ras mutation in the progression of thyroid carcinoma of follicular epithelial origin
Q36293540Somatic RAS mutations occur in a large proportion of sporadic RET-negative medullary thyroid carcinomas and extend to a previously unidentified exon.
Q38614485Thyroid C-Cell Biology and Oncogenic Transformation.
Q77687816Thyroid follicular oncogenesis in iodine-deficient and iodine-sufficient areas: search for alterations of the ras, met and bFGF oncogenes and of the Rb anti-oncogene

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