The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment.

scientific article

The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/2162402X.2018.1434467
P932PMC publication ID5980349
P698PubMed publication ID29872573

P50authorWilliam L RedmondQ53850330
P2093author name stringAnnah S Rolig
Mohammad Farhad
P2860cites workHuman galectin-3 is a novel chemoattractant for monocytes and macrophagesQ22254736
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapseQ24309257
Expression of galectin-3 modulates T-cell growth and apoptosisQ24309392
Galectin-3 Determines Tumor Cell Adaptive Strategies in Stressed Tumor MicroenvironmentsQ26744513
Proteomics. Tissue-based map of the human proteomeQ29617248
IDO and galectin-3 hamper the ex vivo generation of clinical grade tumor-specific T cells for adoptive cell therapy in metastatic melanomaQ33849567
Galectin-3: an open-ended storyQ34494555
Galectin-3 Shapes Antitumor Immune Responses by Suppressing CD8+ T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic CellsQ35329234
Galectin-3 augments tumor initiating property and tumorigenicity of lung cancer through interaction with β-cateninQ35741579
Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages.Q35798551
Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancerQ35908448
Analysis of the intracellular role of galectins in cell growth and apoptosisQ36041236
Galectin-3 as a Potential Target to Prevent Cancer Metastasis.Q36326176
New vistas on macrophage differentiation and activationQ36689930
Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal MetastasisQ36891455
Regulation of prostate cancer progression by galectin-3Q37164578
Endogenous galectins and the control of the host inflammatory responseQ37373062
Galectin-3 regulates T-cell functionsQ37548637
Manipulating Cell Surface Glycoproteins by Targeting N-Glycan–Galectin InteractionsQ37785135
Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancerQ37996614
Glycans and galectins in prostate cancer biology, angiogenesis and metastasisQ38221080
Galectins in cancer: carcinogenesis, diagnosis and therapyQ38269048
Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray studyQ38294425
Expression and function of galectin-3, a beta-galactoside-binding protein in activated T lymphocytesQ38301765
Galectin-3 expressed on different lung compartments promotes organ specific metastasis by facilitating arrest, extravasation and organ colonization via high affinity ligands on melanoma cells.Q38306237
Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexesQ38346878
Increased expression of the LGALS3 (Galectin 3) gene in human non–small‐cell lung cancerQ38355526
Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies.Q39178061
Tumor microenvironment changes leading to resistance of immune checkpoint inhibitors in metastatic melanoma and strategies to overcome resistanceQ39424150
A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumor-infiltrating lymphocytes and favors tumor rejection in miceQ39666028
Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytesQ40002355
Regulation of alternative macrophage activation by galectin-3.Q40016366
Differential expression of galectins in normal, benign and malignant prostate epithelial cells: silencing of galectin-3 expression in prostate cancer by its promoter methylationQ40137078
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell deathQ40333858
Modulation of the biological functions of galectin-3 by matrix metalloproteinasesQ41064679
Metabotropic glutamate receptor 5 may be involved in macrophage plasticityQ41840818
Differential expression of galectin-1 and galectin-3 during first trimester human embryogenesisQ42443034
Galectin-3, a Druggable Vulnerability for KRAS-Addicted CancersQ43465454
Galectin-3 expression in prostate cancer and benign prostate tissues: correlation with biochemical recurrenceQ44523706
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.Q46127843
Galectins: a family of animal beta-galactoside-binding lectinsQ48084852
Proteome-wide Identification of Glycosylation-dependent Interactors of Galectin-1 and Galectin-3 on Mesenchymal Retinal Pigment Epithelial (RPE) Cells.Q48334078
Phylogenetic analysis of the vertebrate galectin family.Q51037036
Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium.Q52551217
Mechanisms of action and rationale for the use of checkpoint inhibitors in cancer.Q55060215
Deletion of galectin-3 in the host attenuates metastasis of murine melanoma by modulating tumor adhesion and NK cell activityQ61903522
Galectin-3 is expressed in the notochord, developing bones, and skin of the postimplantation mouse embryoQ72010083
Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectinQ72770432
Involvement of decreased Galectin-3 expression in the pathogenesis and progression of prostate cancerQ79847221
Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancerQ81126619
Galectin-1 and galectin-3 expression profiles in classically and alternatively activated human macrophagesQ82879773
[The expression of galectin-3 and osteopontin in occult metastasis of non-small cell lung cancer]Q84587668
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 4.0 InternationalQ24082749
P6216copyright statuscopyrightedQ50423863
P433issue6
P921main subjectimmunosuppressionQ1455316
P304page(s)e1434467
P577publication date2018-02-20
P1433published inOncoImmunologyQ18026500
P1476titleThe role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment.
P478volume7

Reverse relations

cites work (P2860)
Q98290574Analysis of prognostic genes in the tumor microenvironment of lung adenocarcinoma
Q92013955Binding of Gold(III) Porphyrin by the Pro-metastatic Regulatory Protein Human Galectin-3
Q57494712Clinical physiology and sleep: highlights from the European Respiratory Society Congress 2018 presented by early career members
Q90073141Galectin-3 as a Next-Generation Biomarker for Detecting Early Stage of Various Diseases
Q98499796Galectin-3 favours tumour metastasis via the activation of β-catenin signalling in hepatocellular carcinoma
Q63979922Galectins in prostate and bladder cancer: tumorigenic roles and clinical opportunities
Q64059939Galectins in the Pathogenesis of Cerebrovascular Accidents: An Overview
Q64274792Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets
Q92143839LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML
Q90690087Multifaceted effects of soluble human CD6 in experimental cancer models
Q92591588Prognostic Impact of Lymphoid Enhancer Factor 1 Expression and Serum Galectin.3 in Egyptian AML Patients
Q92037295Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Q99565582Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling
Q64248384The Natural Cytotoxicity Receptors in Health and Disease
Q92130499The Number of Liver Galectin-3 Positive Cells Is Dually Correlated with NAFLD Severity in Children
Q99552019Trial Watch: experimental TLR7/TLR8 agonists for oncological indications
Q89736315Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function
Q99711529Utilization of Galectins by Pathogens for Infection
Q92362848Vaccinations for Colorectal Cancer: Progress, Strategies, and Novel Adjuvants

Search more.