Polycystin channels and kidney disease.

scientific article

Polycystin channels and kidney disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0165-6147(00)01832-0
P698PubMed publication ID11698076

P2093author name stringZhou J
Stayner C
P2860cites workIdentification of a human homologue of the sea urchin receptor for egg jelly: a polycystic kidney disease-like proteinQ22001473
Identification of PKD2L, a human PKD2-related gene: tissue-specific expression and mapping to chromosome 10q25Q22008623
Polycystin-L is a calcium-regulated cation channel permeable to calcium ionsQ22010635
Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)Q22010947
Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defectsQ24316109
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutationQ24317412
The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domainsQ24336814
Interaction between RGS7 and polycystinQ24653605
Bilineal disease and trans-heterozygotes in autosomal dominant polycystic kidney diseaseQ28345772
Polycystin 1 is required for the structural integrity of blood vesselsQ28512594
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currentsQ29615755
The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channelQ31484726
Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localizationQ33897416
The genetics and physiology of polycystic kidney diseaseQ34179146
Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue.Q35787062
Identification and characterization of polycystin-2, the PKD2 gene productQ38320261
The pathology of human renal cystic disease.Q40447184
The polycystic kidney disease 1 gene product modulates Wnt signalingQ40973635
The endoplasmic reticulum Ca2+ store: a view from the lumenQ41710104
Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney diseaseQ42645641
Multilocus polycystic diseaseQ44412153
The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitroQ48364885
Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X.Q50716491
Genetic evidence for a trans-heterozygous model for cystogenesis in autosomal dominant polycystic kidney disease.Q52171297
Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations.Q53879309
Polycystic kidney disease: The complete structure of the PKD1 gene and its proteinQ56535688
The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1Q74299216
Somatic inactivation of Pkd2 results in polycystic kidney diseaseQ74502174
Identification of phosphorylation sites in the PKD1-encoded protein C-terminal domainQ77854949
Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domainQ77865503
P433issue11
P304page(s)543-546
P577publication date2001-11-01
P1433published inTrends in Pharmacological SciencesQ2451474
P1476titlePolycystin channels and kidney disease.
P478volume22

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cites work (P2860)
Q42621739A third sea urchin sperm receptor for egg jelly module protein, suREJ2, concentrates in the plasma membrane over the sperm mitochondrion
Q35822230Calcium at fertilization and in early development
Q24314239Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells
Q53551189Differences in renal tubule primary cilia length in a mouse model of Bardet-Biedl syndrome.
Q40673214Expression of polycystin-1 C-terminal fragment enhances the ATP-induced Ca2+ release in human kidney cells
Q35094105From genes to integrative physiology: ion channel and transporter biology in Caenorhabditis elegans
Q34582336Intracellular calcium release modulates polycystin-2 trafficking
Q35916409Invertebrate TRP proteins as functional models for mammalian channels
Q24297056Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2
Q28505110Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
Q28260546Regulation of calcium signaling by polycystin-2
Q40450435The cytoplasmic C-terminus of polycystin-1 increases cell proliferation in kidney epithelial cells through serum-activated and Ca(2+)-dependent pathway(s).
Q24292360The sequence, expression, and chromosomal localization of a novel polycystic kidney disease 1-like gene, PKD1L1, in human
Q30834303Virtual-tissue computer simulations define the roles of cell adhesion and proliferation in the onset of kidney cystic disease

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