Enhanced expression of Giα proteins contributes to the hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats via MAP kinase- and PI3 kinase-independent pathways

scientific article

Enhanced expression of Giα proteins contributes to the hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats via MAP kinase- and PI3 kinase-independent pathways is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1139/CJPP-2015-0146
P698PubMed publication ID26524499

P2093author name stringYuan Li
Madhu B Anand-Srivastava
Grace Bou Daou
P2860cites workModulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiologyQ34059645
G proteins and dual control of adenylate cyclaseQ34255388
Heterotrimeric G proteins: organizers of transmembrane signalsQ34317073
Human cDNA clones for four species of G alpha s signal transduction proteinQ36426004
Role of Cyclic Nucleotides in Growth ControlQ36465841
The reaction of glucagon with its receptor: evidence for discrete regions of activity and binding in the glucagon moleculeQ37474698
The cyclic AMP-mediated stimulation of cell proliferationQ38268154
Role of epidermal growth factor receptor transactivation in endothelin-1-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cellsQ39174251
Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cellsQ39316460
Small cytoplasmic domain peptides of natriuretic peptide receptor-C attenuate cell proliferation through Gialpha protein/MAP kinase/PI3-kinase/AKT pathwaysQ40241686
Hypertensive sodium-proton exchanger phenotype persists in immortalized lymphoblasts from essential hypertensive patients. A cell culture model for human hypertensionQ40305844
Enhanced G protein activation in immortalized lymphoblasts from patients with essential hypertension.Q41318399
Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growthQ42511887
Enhanced expression of inhibitory guanine nucleotide regulatory protein in spontaneously hypertensive rats. Relationship to adenylate cyclase inhibitionQ42796280
Lymphocytes from spontaneously hypertensive rats exhibit enhanced adenylyl cyclase-Gi protein signalingQ43512555
Inactivation of enhanced expression of G(i) proteins by pertussis toxin attenuates the development of high blood pressure in spontaneously hypertensive ratsQ44095813
The G protein-gated atrial K+ channel is stimulated by three distinct Gi alpha-subunitsQ44104764
Altered expression of G-protein mRNA in spontaneously hypertensive ratsQ44707739
Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteinsQ44858371
Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHRQ45577207
H2O2-induced phosphorylation of ERK1/2 and PKB requires tyrosine kinase activity of insulin receptor and c-SrcQ46584373
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive ratsQ46790688
Refinement of the Coomassie brilliant blue G assay for quantitative protein determinationQ50890041
cAMP attenuates the enhanced expression of Gi proteins and hyperproliferation of vascular smooth muscle cells from SHR: role of ROS and ROS-mediated signalingQ51075050
Evidence for hyperplasia in mesenteric resistance vessels of spontaneously hypertensive rats using a three-dimensional disectorQ54441587
Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHRQ54578386
Enhanced levels of endogenous endothelin-1 contribute to the over expression of Giα protein in vascular smooth muscle cells from SHR: Role of growth factor receptor activationQ54641259
P433issue1
P304page(s)49-58
P577publication date2015-06-18
P1433published inCanadian Journal of Physiology and PharmacologyQ5030248
P1476titleEnhanced expression of Giα proteins contributes to the hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats via MAP kinase- and PI3 kinase-independent pathways
P478volume94

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cites work (P2860)
Q48173752Contribution of oxidative stress and growth factor receptor transactivation in natriuretic peptide receptor C-mediated attenuation of hyperproliferation of vascular smooth muscle cells from SHR.
Q53823179Inhibition of overexpression of Giα proteins and nitroxidative stress contribute to sodium nitroprusside-induced attenuation of high blood pressure in SHR.
Q37556115Knockdown of Inhibitory Guanine Nucleotide Binding Protein Giα-2 by Antisense Oligodeoxynucleotides Attenuates the Development of Hypertension and Tachycardia in Spontaneously Hypertensive Rats
Q50126148Natriuretic peptide receptor-C activation attenuates angiotensin II-induced enhanced oxidative stress and hyperproliferation of aortic vascular smooth muscle cells
Q33888027Nitric oxide attenuates overexpression of Giα proteins in vascular smooth muscle cells from SHR: Role of ROS and ROS-mediated signaling
Q47255917Resveratrol attenuates hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats: Role of ROS and ROS-mediated cell signaling

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