Degradation of HaloTag-fused nuclear proteins using bestatin-HaloTag ligand hybrid molecules.

scientific article

Degradation of HaloTag-fused nuclear proteins using bestatin-HaloTag ligand hybrid molecules. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C5OB01395J
P698PubMed publication ID26338696

P50authorMinoru IshikawaQ59167430
Shusuke TomoshigeQ86069835
P2093author name stringYuichi Hashimoto
Mikihiko Naito
P2860cites workHaloTag: a novel protein labeling technology for cell imaging and protein analysisQ42809086
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Photodegradation and inhibition of drug-resistant influenza virus neuraminidase using anthraquinone-sialic acid hybrids.Q45353233
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Design, synthesis and biological evaluation of nuclear receptor-degradation inducers.Q34225932
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4.Q34478968
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.Q34479551
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Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACsQ36895558
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Regulation of target protein knockdown and labeling using ligand-directed Ru(bpy)3 photocatalystQ38924509
Double protein knockdown of cIAP1 and CRABP-II using a hybrid molecule consisting of ATRA and IAPs antagonist.Q39338448
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Small-molecule displacement of a cryptic degron causes conditional protein degradationQ39513760
Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein.Q39574650
Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins.Q39718603
An auxin-based degron system for the rapid depletion of proteins in nonplant cells.Q39774277
Direct pH measurements by using subcellular targeting of 5(and 6-) carboxyseminaphthorhodafluor in mammalian cellsQ39784169
Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancerQ39939428
Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.Q40533310
Chemical genetic control of protein levels: selective in vivo targeted degradationQ40574972
General method for regulating protein stability with lightQ41900311
A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small moleculesQ42166429
Rapid control of protein level in the apicomplexan Toxoplasma gondiiQ42714117
P433issue38
P304page(s)9746-9750
P577publication date2015-10-01
P1433published inOrganic and Biomolecular ChemistryQ3355939
P1476titleDegradation of HaloTag-fused nuclear proteins using bestatin-HaloTag ligand hybrid molecules
P478volume13

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cites work (P2860)
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Q34545841Induced protein degradation: an emerging drug discovery paradigm
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Q58756135Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase
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Q38978952Targeted Protein Degradation by Small Molecules
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