Honokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations.

scientific article published on 24 April 2018

Honokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations. is …
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scholarly articleQ13442814

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P356DOI10.3389/FPHAR.2018.00357
P932PMC publication ID5932397
P698PubMed publication ID29755347

P50authorChi-Chung ChouQ86103803
P2093author name stringYu-Hua Lai
Hui-Wen Chang
Naohiro Nomura
Tong-Rong Jan
Ya-Jane Lee
Pei-Shiue J Tsai
Hung-Ting Liu
Tse-En J Wang
P2860cites workThe anti-inflammatory effect of honokiol on neutrophils: mechanisms in the inhibition of reactive oxygen species productionQ44572473
New perspectives on mechanisms involved in generating epithelial cell polarityQ46889799
Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice HippocampusQ48156996
Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in miceQ48305206
Honokiol inhibits migration of renal cell carcinoma through activation of RhoA/ROCK/MLC signaling pathway.Q51501782
Relationships between cisplatin-induced adducts and DNA strand-breaks, mutation and recombination in vivo in somatic cells of Drosophila melanogaster, under different conditions of nucleotide excision repair.Q52731075
Time and dose-response effects of honokiol on UVB-induced skin cancer development.Q53266187
Hydroxyl radical scavenger ameliorates cisplatin-induced nephrotoxicity by preventing oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria.Q53562512
Renal tight junction proteins are decreased in cisplatin-induced nephrotoxicity in rats.Q55072805
Clinicopathological Variables Predicting Progression of Azotemia in Cats with Chronic Kidney DiseaseQ59665931
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Acute renal failureQ71051154
Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in ratsQ86873379
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Utility of antioxidants during assisted reproductive techniques: an evidence based reviewQ27023797
An integrated view of cisplatin-induced nephrotoxicity and ototoxicityQ28080615
Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivoQ28180577
Pharmacokinetics of honokiol after intravenous administration in rats assessed using high-performance liquid chromatographyQ28246652
Plakins: goliaths that link cell junctions and the cytoskeletonQ28270016
Anti-inflammatory bioactivities of honokiol through inhibition of protein kinase C, mitogen-activated protein kinase, and the NF-kappaB pathway to reduce LPS-induced TNFalpha and NO expressionQ28274580
Identification, characterization and purification of porcine Quiescin Q6-Sulfydryl Oxidase 2 protein.Q32175870
Improved therapeutic effectiveness by combining liposomal honokiol with cisplatin in lung cancer modelQ33360446
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Honokiol and Magnolol as Multifunctional Antioxidative Molecules for Dermatologic DisordersQ34140583
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Particular aspects of platinum compounds used at present in cancer treatmentQ34671647
Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthmaQ35400401
Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS GenerationQ35738714
Recognition and processing of cisplatin- and oxaliplatin-DNA adductsQ35988488
New insights into the dynamic regulation of water and acid-base balance by renal epithelial cells.Q35993741
Synergistic antitumor effects of liposomal honokiol combined with cisplatin in colon cancer modelsQ36126660
Oxidative stress and autophagy: crucial modulators of kidney injuryQ36717785
Honokiol is a potent scavenger of superoxide and peroxyl radicalsQ36954777
Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicityQ37155362
Epithelial cell-cell junctions and plasma membrane domainsQ37245010
In vitro studies of actin filament and network dynamicsQ38069843
Kidney slices of human and rat to characterize cisplatin-induced injury on cellular pathways and morphologyQ38333066
Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesisQ38740399
Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamicsQ38851414
Honokiol inhibits LPS-induced maturation and inflammatory response of human monocyte-derived dendritic cells.Q39527075
Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppressionQ40031034
Alterations in epithelial polarity and the pathogenesis of disease statesQ40749830
Effects of constituents from the bark of Magnolia obovata on nitric oxide production in lipopolysaccharide-activated macrophagesQ40798441
Establishing a High-content Analysis Method for Tubulin Polymerization to Evaluate Both the Stabilizing and Destabilizing Activities of CompoundsQ41830818
Basolateral targeting and microtubule-dependent transcytosis of the aquaporin-2 water channel.Q42053033
Insights into potential cellular mechanisms of cisplatin nephrotoxicity and their clinical applicationQ44242969
Changes in glutathione-related enzymes in tumor-bearing mice after cisplatin treatmentQ44250929
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P921main subjectcytoskeletonQ154626
polyphenolQ290439
P304page(s)357
P577publication date2018-04-24
P1433published inFrontiers in PharmacologyQ2681208
P1476titleHonokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations
P478volume9

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Q90632926Nanoparticulated Honokiol Mitigates Cisplatin-Induced Chronic Kidney Injury by Maintaining Mitochondria Antioxidant Capacity and Reducing Caspase 3-Associated Cellular Apoptosiscites workP2860

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