Nutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells.

scientific article published on 8 May 2018

Nutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FMOLB.2018.00045
P932PMC publication ID5952004
P698PubMed publication ID29868606

P50authorMikaela M CederQ47160153
Robert FredrikssonQ79695518
P2093author name stringSofie V Hellsten
Rekha Tripathi
P2860cites workSLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1Q24312292
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1Q24313010
Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter geneQ24543931
mTOR signaling in growth control and diseaseQ24634174
Role of amino acid transporters in amino acid sensingQ26999339
Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TORQ27001717
Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9Q42024304
SAT1, A Glutamine Transporter, is Preferentially Expressed in GABAergic NeuronsQ42137583
SNAT7 is the primary lysosomal glutamine exporter required for extracellular protein-dependent growth of cancer cellsQ43083637
Nitrogen shuttling between neurons and glial cells during glutamate synthesisQ43548198
Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein responseQ44155944
Metabolic signaling in the brain and the role of astrocytes in control of glutamate and GABA neurotransmissionQ47834253
Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS.Q48433931
Amino acid regulation of gene expressionQ74347727
The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.Q27863346
The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroductionQ28185295
Distribution of key enzymes of branched-chain amino acid metabolism in glial and neuronal cells in cultureQ28200176
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
Highly differential expression of SN1, a bidirectional glutamine transporter, in astroglia and endothelium in the developing rat brainQ28570234
A novel system A isoform mediating Na+/neutral amino acid cotransportQ28570693
Immunohistochemical localization of the amino acid transporter SNAT2 in the rat brainQ28581137
Identification of SLC38A7 (SNAT7) protein as a glutamine transporter expressed in neuronsQ28587492
Histological analysis of SLC38A6 (SNAT6) expression in mouse brain shows selective expression in excitatory neurons with high expression in the synapsesQ28592395
Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons.Q30913408
The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38.Q33328866
The neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission.Q33762641
The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in miceQ34286263
Amino acid signalling upstream of mTORQ34325138
The ABCs of membrane transporters in health and disease (SLC series): introductionQ34333686
Impact of forskolin and amino acid depletion upon System A activity and SNAT expression in BeWo cellsQ34446235
Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2alpha phosphorylation and cap-independent translation.Q34514695
The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient IntakeQ34547480
Amino acid transporter SNAT5 localizes to glial cells in the rat brain.Q34649882
Nutrient-sensing mechanisms and pathways.Q35036374
Amino acid transporters: roles in amino acid sensing and signalling in animal cellsQ35184476
Nutritional control of gene expression: how mammalian cells respond to amino acid limitationQ36191074
The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat dietQ36290259
The solute carrier 6 family of transportersQ36346899
Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.Q37065899
Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signalingQ37374064
Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspectsQ38090789
The SLC38 family of sodium-amino acid co-transporters.Q38160180
Activation of the human asparagine synthetase gene by the amino acid response and the endoplasmic reticulum stress response pathways occurs by common genomic elementsQ38311346
Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylationQ38347783
Amino Acid transporters in cancer and their relevance to "glutamine addiction": novel targets for the design of a new class of anticancer drugsQ38412222
The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvationQ38717414
Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathwaysQ39899171
Glutamine transport. From energy supply to sensing and beyondQ39941261
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P304page(s)45
P577publication date2018-05-08
P1433published inFrontiers in molecular biosciencesQ27726420
P1476titleNutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells
P478volume5

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cites work (P2860)
Q98178404Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster
Q89620059Knockdown of SLC38 Transporter Ortholog - CG13743 Reveals a Metabolic Relevance in Drosophila
Q90570121The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer

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