Intravenous morphine versus intravenous paracetamol after cardiac surgery in neonates and infants: a study protocol for a randomized controlled trial.

scientific article published on 13 June 2018

Intravenous morphine versus intravenous paracetamol after cardiac surgery in neonates and infants: a study protocol for a randomized controlled trial. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1104551922
P356DOI10.1186/S13063-018-2705-5
P932PMC publication ID5998570
P698PubMed publication ID29895289

P50authorGreet Van den BergheQ41203524
Dick TibboelQ88459455
P2093author name stringAd J J C Bogers
Nicolaas J G Jansen
Monique van Dijk
Joost van Rosmalen
Enno D Wildschut
Martin C J Kneyber
Erik Koomen
Dirk Vlasselaers
Gerdien A Zeilmaker-Roest
Sofie Maebe
P2860cites workBirth prevalence of congenital heart disease worldwide: a systematic review and meta-analysisQ27013736
Effect of neonatal circumcision on pain response during subsequent routine vaccinationQ28305181
OCT1 genetic variants influence the pharmacokinetics of morphine in children.Q33977906
ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in childrenQ34308014
PRISM III: an updated Pediatric Risk of Mortality scoreQ34389009
Cardiopulmonary bypass and the systemic inflammatory response: effects on drug actionQ34538194
The impact of genetic variation on sensitivity to opioid analgesics in patients with postoperative pain: a systematic review and meta-analysisQ35582801
Anesthesia and analgesia during and after surgery in neonates.Q36238791
Opioid analgesia in neonates following cardiac surgeryQ36813077
Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosisQ37004604
Good practice in postoperative and procedural pain management, 2nd editionQ38027898
The effect of adult and pediatric cardiopulmonary bypass on pharmacokinetic and pharmacodynamic parametersQ38067759
Minimizing systemic inflammation during cardiopulmonary bypass in the pediatric populationQ38176052
A review of the role of genetic testing in pain medicineQ38253449
Pharmacogenomics of acetaminophen in pediatric populations: a moving targetQ38263519
Effect of intravenous paracetamol on postoperative morphine requirements in neonates and infants undergoing major noncardiac surgery: a randomized controlled trialQ38458158
Paracetamol (acetaminophen) for prevention or treatment of pain in newborns.Q38975143
Intravenous acetaminophen (paracetamol): comparable analgesic efficacy, but better local safety than its prodrug, propacetamol, for postoperative pain after third molar surgeryQ39365407
Morphine glucuronidation in preterm neonates, infants and children younger than 3 yearsQ39958347
Construction of the Sophia Observation withdrawal Symptoms-scale (SOS) for critically ill childrenQ39987511
Cornell Assessment of Pediatric Delirium: a valid, rapid, observational tool for screening delirium in the PICU*.Q40144936
The COMFORT behaviour scale detects clinically meaningful effects of analgesic and sedative treatment.Q40210765
Antipyretic efficacy and tolerability of a single intravenous dose of the acetaminophen prodrug propacetamol in children: a randomized, double-blind, placebo-controlled trial.Q40474014
Weaning of opioids and benzodiazepines at home after critical illness in infants: a cost-effective approach.Q43125347
Nurse-controlled analgesia (NCA) following major surgery in 10,000 patients in a children's hospitalQ43192899
Analgesic efficacy of rectal versus oral acetaminophen in children after major craniofacial surgeryQ43673176
Developmental changes in morphine clearance across the entire paediatric age range are best described by a bodyweight-dependent exponent model.Q43810147
Paracetamol and metabolite pharmacokinetics in infants.Q44450122
PELOD-2: an update of the PEdiatric logistic organ dysfunction scoreQ44577426
Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administrationQ44778047
Population pharmacokinetics of single-dose intravenous paracetamol in childrenQ46140205
A comparison of pain measures in newborn infants after cardiac surgeryQ46271078
Pediatric intravenous paracetamol (propacetamol) pharmacokinetics: a population analysis.Q46401554
Pharmacodynamics and Pharmacokinetics of Morphine After Cardiac Surgery in Children With and Without Down Syndrome.Q47399812
Paracetamol (acetaminophen) penetrates readily into the cerebrospinal fluid of children after intravenous administrationQ48220180
Sophia Observation withdrawal Symptoms-Paediatric Delirium scale: A tool for early screening of delirium in the PICU.Q48599689
Continuous Intravenous Acetaminophen for Analgesia: First, Back to the Drawing Table?Q50200383
The RACHS-1 risk categories reflect mortality and length of stay in a Danish population of children operated for congenital heart disease.Q50542803
Psychometric evaluation of the Sophia Observation withdrawal symptoms scale in critically ill children.Q50781044
Consequences of inadequate analgesia during painful procedures in children.Q51099035
A new and improved confidence interval for the Mantel-Haenszel risk difference.Q51104692
Evidence-based morphine dosing for postoperative neonates and infants.Q51115933
Predictive Performance of a Recently Developed Population Pharmacokinetic Model for Morphine and its Metabolites in New Datasets of (Preterm) Neonates, Infants and Children.Q51618909
Rectal acetaminophen does not reduce morphine consumption after major surgery in young infants.Q51922805
The reliability and validity of the COMFORT scale as a postoperative pain instrument in 0 to 3-year-old infants.Q52918951
Hemodynamic effects of intravenous morphine infusion in ventilated preterm babies.Q53973322
The COMFORT-Behavior scale is useful to assess pain and distress in 0- to 3-year-old children with Down syndromeQ56919881
Congenital Heart Defects in Europe: Prevalence and Perinatal Mortality, 2000 to 2005Q57077337
Measuring the severity of surgical stress in newborn infantsQ57394750
Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: patient comfortQ57545523
Development of a 10-Item Short Form of the Parents’ Postoperative Pain Measure: The PPPM-SFQ60511626
Morphine pharmacokinetics in children following cardiac surgery: effects of disease and inotropic supportQ70482583
Respiratory effects of intravenous morphine infusions in neonates, infants, and children after cardiac surgeryQ72543675
Early extubation after cardiac operations in neonates and young infantsQ73716371
Clearance of morphine in postoperative infants during intravenous infusion: the influence of age and surgeryQ74539808
Assessment of sedation levels in pediatric intensive care patients can be improved by using the COMFORT "behavior" scaleQ81239136
The Aristotle Comprehensive Complexity score predicts mortality and morbidity after congenital heart surgeryQ83722844
Comparative study of the Aristotle Comprehensive Complexity and the Risk Adjustment in Congenital Heart Surgery scoresQ84837398
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectparacetamolQ57055
study protocolQ111908491
P304page(s)318
P577publication date2018-06-13
P1433published inTrialsQ7840023
P1476titleIntravenous morphine versus intravenous paracetamol after cardiac surgery in neonates and infants: a study protocol for a randomized controlled trial.
P478volume19

Reverse relations

Q89584499Nonopioid analgesics for perioperative and cardiac surgery pain in children: Current evidence and knowledge gapscites workP2860

Search more.