A Brief History of Microglial Ultrastructure: Distinctive Features, Phenotypes, and Functions Discovered Over the Past 60 Years by Electron Microscopy.

scientific article published on 25 April 2018

A Brief History of Microglial Ultrastructure: Distinctive Features, Phenotypes, and Functions Discovered Over the Past 60 Years by Electron Microscopy. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2018.00803
P932PMC publication ID5996933
P698PubMed publication ID29922276

P2093author name stringJulie C Savage
Marie-Ève Tremblay
Katherine Picard
Fernando González-Ibáñez
P2860cites workSectioning techniques for electron microscopy using a conventional microtomeQ82320418
Serial block-face scanning electron microscopy to reconstruct three-dimensional tissue nanostructureQ21563638
From the Cajal alumni Achúcarro and Río-Hortega to the rediscovery of never-resting microgliaQ26851257
Microglial pathologyQ26992285
Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke.Q27317371
Microglial interactions with synapses are modulated by visual experienceQ27322943
Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex.Q27325419
Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopyQ27684426
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivoQ27860578
Microglia sculpt postnatal neural circuits in an activity and complement-dependent mannerQ28267444
Microglia-specific localisation of a novel calcium binding protein, Iba1Q28273977
Cryo-electron microscopy of vitrified specimensQ28288841
Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cellsQ28395128
Morphological and ultrastructural features of Iba1-immunolabeled microglial cells in the hippocampal dentate gyrusQ28577737
Conventional transmission electron microscopyQ28659693
ATP mediates rapid microglial response to local brain injury in vivoQ29547872
Synaptic pruning by microglia is necessary for normal brain developmentQ29615591
Fate mapping analysis reveals that adult microglia derive from primitive macrophagesQ29616177
Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminalsQ29619476
Microglia: Dynamic Mediators of Synapse Development and Plasticity.Q30373424
Site-specific 3D imaging of cells and tissues with a dual beam microscopeQ30478318
THE FINE STRUCTURE OF THE RAT CEREBELLUM. II. THE STELLATE NEURONS, GRANULE CELLS, AND GLIA.Q30494639
Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammationQ30581791
Microglial displacement of inhibitory synapses provides neuroprotection in the adult brainQ30584811
Differential roles of microglia and monocytes in the inflamed central nervous systemQ30585165
Electron microscopy of neurons and neuroglia of cerebral cortex and corpus callosum.Q51326381
Neuroglial structure and relationships as revealed by electron microscopy.Q51328638
Glia engulf degenerating axons during developmental axon pruning.Q52090523
Serial Section Scanning Electron Microscopy of Adult Brain Tissue Using Focused Ion Beam MillingQ64868700
Displacement of synaptic terminals from regenerating motoneurons by microglial cellsQ72179911
A new microtome for ultrathin sectioning for high resolution electron microscopyQ73202603
A diamond knife for ultrathin sectioningQ73255531
COMPARISON OF OSMIUM TETROXIDE AND GLUTARALDEHYDE PERFUSION FIXATION FOR THE ELECTRON MICROSCOPIC STUDY OF THE NORMAL RAT PERIPHERAL NERVOUS SYSTEMQ76684073
Microglia across the lifespan: from origin to function in brain development, plasticity and cognitionQ38814802
How neuroinflammation contributes to neurodegenerationQ38931554
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammationQ39342489
Extending unbiased stereology of brain ultrastructure to three-dimensional volumesQ39677324
Correlative light-electron microscopy (CLEM) combining live-cell imaging and immunolabeling of ultrathin cryosectionsQ39922934
Cryo-electron microscopy of vitreous sections of native biological cells and tissuesQ41628091
In situ RT-PCR Optimized for Electron Microscopy Allows Description of Subcellular Morphology of Target mRNA-Expressing Cells in the BrainQ41813553
Preparation of mouse brain tissue for immunoelectron microscopyQ41894749
APPLICATIONS OF A DIAMOND KNIFE FOR ULTRATHIN SECTIONING TO THE STUDY OF THE FINE STRUCTURE OF BIOLOGICAL TISSUES AND METALSQ41939846
Dark microglia: A new phenotype predominantly associated with pathological states.Q42094554
Electron microscopic evidence for microglial phagocytic activity and cholinergic cell death after administration of the immunotoxin 192IgG-saporin in rat.Q42439636
An improved method for perfusion fixation of neural tissues for electron microscopyQ42443641
3D electron tomography of brain tissue unveils distinct Golgi structures that sequester cytoplasmic contents in neurons.Q42497411
Mapping of fluorescent protein-expressing neurons and axon pathways in adult and developing Thy1-eYFP-H transgenic mice.Q43050807
The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexesQ43240413
Characterization of ameboid microglia isolated from developing mammalian brain.Q43766815
The "Big-Bang" for modern glial biology: Translation and comments on Pío del Río-Hortega 1919 series of papers on microgliaQ47658635
Microglia and macrophages differ in their inflammatory profile after permanent brain ischemiaQ47901681
Fractalkine receptor deficiency impairs microglial and neuronal responsiveness to chronic stressQ48076909
Quantitative and ultrastructural changes in glia and pericytes in the parietal cortex of the aging rat.Q48342121
Intracerebral Injections and Ultrastructural Analysis of High-Pressure Frozen Brain TissueQ48374186
Spine growth precedes synapse formation in the adult neocortex in vivo.Q48453516
Microglia modulate wiring of the embryonic forebrainQ48583475
Inhomogeneous distribution of Iba-1 characterizes microglial pathology in Alzheimer's diseaseQ48627278
Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: a light, confocal, and electron microscopical study using a phagocytosis-dependent labeling techniqueQ48698640
Identification of microglia in light and electron microscopyQ49117316
Morphological studies on neuroglia. V. Microglial cells in the cerebral cortex of the rat, with special reference to their possible involvement in synaptic functionQ49126592
Prenatal Immune Challenge in Mice Leads to Partly Sex-Dependent Behavioral, Microglial, and Molecular Abnormalities Associated with SchizophreniaQ50152745
Ultrastructural in situ hybridization: a review of technical aspectsQ31944880
Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuitsQ33289933
Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.Q33662701
A complement-microglial axis drives synapse loss during virus-induced memory impairmentQ33750562
Microglia in infectious diseases of the central nervous systemQ33760767
Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration researchQ33847412
Light and electron microscopic and cytochemical identification of amoeboid microglial cells in the brain of prenatal ratsQ33891712
Cryo electron tomography of herpes simplex virus during axonal transport and secondary envelopment in primary neurons.Q34109746
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.Q34123789
Ptychographic electron microscopy using high-angle dark-field scattering for sub-nanometre resolution imaging.Q34186666
CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.Q34254575
Reconstruction of three dimensional structures from electron micrographsQ34682297
A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse modelQ34746889
Semiautomated correlative 3D electron microscopy of in vivo-imaged axons and dendritesQ35169616
Does super-resolution fluorescence microscopy obsolete previous microscopic approaches to protein co-localization?Q35564950
Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixationQ35932244
Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid PlaquesQ36048502
Fixation of neural tissues for electron microscopy by perfusion with solutions of osmium tetroxideQ36184982
Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixationQ36185660
A STUDY OF EXTRACELLULAR SPACE IN CENTRAL NERVOUS TISSUE BY FREEZE-SUBSTITUTIONQ36186794
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.Q36190713
Distinction of Neurons, Glia and Endothelial Cells in the Cerebral Cortex: An Algorithm Based on Cytological FeaturesQ36193595
Priming the inflammatory pump of the CNS after traumatic brain injuryQ36198332
Extracellular space preservation aids the connectomic analysis of neural circuitsQ36610062
Two-photon excitation STED microscopy in two colors in acute brain slicesQ36621997
An introduction to sample preparation and imaging by cryo-electron microscopy for structural biologyQ36861835
Neurotransmitter receptors on microglia.Q36955350
Extracellular vesicles are present in mouse lymph and their level differs in atherosclerosisQ37280859
The microglial sensome revealed by direct RNA sequencingQ37341692
Degenerating synaptic boutons in prion disease: microglia activation without synaptic strippingQ37362101
Neurotransmitter signaling in the pathophysiology of microgliaQ38102686
Exploring the third dimension: volume electron microscopy comes of age.Q38208994
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathwaysQ38550041
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectmicrogliaQ1622829
cellQ7868
nervous systemQ9404
biomedical investigative techniqueQ66648976
P304page(s)803
P577publication date2018-04-25
P1433published inFrontiers in ImmunologyQ27723748
P1476titleA Brief History of Microglial Ultrastructure: Distinctive Features, Phenotypes, and Functions Discovered Over the Past 60 Years by Electron Microscopy.
P478volume9