Recent Advances and Ongoing Challenges in the Diagnosis of Microbial Infections by MALDI-TOF Mass Spectrometry.

scientific article

Recent Advances and Ongoing Challenges in the Diagnosis of Microbial Infections by MALDI-TOF Mass Spectrometry. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FMICB.2018.01097
P932PMC publication ID5986882
P698PubMed publication ID29896172

P50authorEmilia GhelardiQ57235287
P2093author name stringArianna Tavanti
Antonella Lupetti
Walter Florio
Simona Barnini
P2860cites workMatrix-assisted laser desorption/ionization time-of-flight mass spectrometry identification of mycobacteria in routine clinical practiceQ21089935
Discrimination of Penicillium isolates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry fingerprintingQ23915626
Identification of mycobacteria by matrix-assisted laser desorption ionization-time-of-flight mass spectrometryQ24549069
Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based functional assay for rapid detection of resistance against β-lactam antibioticsQ24623358
Mould routine identification in the clinical laboratory by matrix-assisted laser desorption ionization time-of-flight mass spectrometryQ28478418
Characterizing the Syphilis-Causing Treponema pallidum ssp. pallidum Proteome Using Complementary Mass SpectrometryQ28553940
Detection of Staphylococcus aureus delta-toxin production by whole-cell MALDI-TOF mass spectrometryQ28727420
Identification of rare pathogenic bacteria in a clinical microbiology laboratory: impact of matrix-assisted laser desorption ionization-time of flight mass spectrometryQ29616596
Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometryQ29616600
SpectraBank: an open access tool for rapid microbial identification by MALDI-TOF MS fingerprintingQ30485598
Characterization of the protein subset desorbed by MALDI from whole bacterial cellsQ30658522
Assessment of a novel bile solubility test and MALDI-TOF for the differentiation of Streptococcus pneumoniae from other mitis group streptococciQ41221106
Epidemiology of Invasive Fungal Disease in ChildrenQ41996461
Saponin promotes rapid identification and antimicrobial susceptibility profiling of Gram-positive and Gram-negative bacteria in blood cultures with the Vitek 2 system.Q44907928
A novel liquid media mycobacteria extraction method for MALDI-TOF MS identification using VITEK® MS.Q46257716
Total Laboratory Automation and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Improve Turnaround Times in the Clinical Microbiology Laboratory: a Retrospective AnalysisQ47140359
Rapid and cost-effective identification and antimicrobial susceptibility testing in patients with Gram-negative bacteremia directly from blood-culture fluidQ47549223
Rapid detection of antibiotic resistance by MALDI-TOF mass spectrometry using a novel direct-on-target microdroplet growth assayQ50099636
Accuracy of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Mycobacteria: a systematic review and meta-analysis.Q52363941
Rapid identification and antimicrobial susceptibility testing of Gram-positive cocci in blood cultures by direct inoculation into the BD Phoenix systemQ84405808
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry identifies 90% of bacteria directly from blood culture vialsQ84999467
Integrating Rapid Diagnostics and Antimicrobial Stewardship in Two Community Hospitals Improved Process Measures and Antibiotic Adjustment TimeQ35887408
Shortcomings of the Commercial MALDI-TOF MS Database and Use of MLSA as an Arbiter in the Identification of Nocardia SpeciesQ36009140
The impact of protein extraction protocols on the performance of currently available MALDI-TOF mass spectrometry for identification of mycobacterial clinical isolates cultured in liquid mediaQ36068471
A new rapid method for direct antimicrobial susceptibility testing of bacteria from positive blood culturesQ36103297
Application of Mass Spectrometry Technology to Early Diagnosis of Invasive Fungal InfectionsQ36125981
Evaluation of MALDI-TOF MS (Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry) for routine identification of anaerobic bacteriaQ36152963
Accurate Differentiation of Streptococcus pneumoniae from other Species within the Streptococcus mitis Group by Peak Analysis Using MALDI-TOF MS.Q36367462
Changes in incidence and antifungal drug resistance in candidemia: results from population-based laboratory surveillance in Atlanta and Baltimore, 2008-2011.Q36423773
Rapid identification of intact whole bacteria based on spectral patterns using matrix-assisted laser desorption/ionization with time-of-flight mass spectrometryQ36813916
Treatment of fungal disease in the setting of neutropeniaQ38169668
Proteome-based bacterial identification using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS): A revolutionary shift in clinical diagnostic microbiologyQ38275270
Emerging issues, challenges, and changing epidemiology of fungal disease outbreaksQ38647201
Mass spectrometry applications in microbiology beyond microbe identification: progress and potentialQ38824041
Rapid Detection and Identification of Candidemia by Direct Blood Culturing on Solid Medium by Use of Lysis-Centrifugation Method Combined with Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS).Q39235326
Septic shock attributed to Candida infection: importance of empiric therapy and source controlQ40026437
Application of MALDI-TOF MS fingerprinting as a quick tool for identification and clustering of foodborne pathogens isolated from food productsQ40085997
Fatal cutaneous mucormycosis after kidney transplantQ40183932
Improving outcome of fungal diseases - Guiding experts and patients towards excellenceQ40204390
Identification of Staphylococcus aureus and determination of its methicillin resistance by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Q30755631
Characterization of protein biomarkers desorbed by MALDI from whole fungal cellsQ30768803
Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008.Q30834974
Direct identification of bacteria in positive blood culture bottles by matrix-assisted laser desorption ionisation time-of-flight mass spectrometryQ30927749
Rapid identification of bacteria in positive blood culture broths by matrix-assisted laser desorption ionization-time of flight mass spectrometryQ30940160
Analysis of the matrix-assisted laser desorption ionization-time of flight mass spectrum of Staphylococcus aureus identifies mutations that allow differentiation of the main clonal lineagesQ31114419
Impact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemiaQ31125537
Matrix-assisted laser desorption ionization-time of flight mass spectrometry for fast and reliable identification of clinical yeast isolatesQ33477230
Identification of clinical coagulase-negative staphylococci, isolated in microbiology laboratories, by matrix-assisted laser desorption/ionization-time of flight mass spectrometry and two automated systems.Q33500300
Comparison of two matrix-assisted laser desorption ionization-time of flight mass spectrometry methods with conventional phenotypic identification for routine identification of bacteria to the species levelQ33531989
Rapid identification of bacteria from positive blood culture bottles by use of matrix-assisted laser desorption-ionization time of flight mass spectrometry fingerprintingQ33541809
Microorganisms direct identification from blood culture by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Q33574046
First outbreak of PVL-positive nonmultiresistant MRSA in a neonatal ICU in Australia: comparison of MALDI-TOF and SNP-plus-binary gene typing.Q33605056
Improved identification of yeast species directly from positive blood culture media by combining Sepsityper specimen processing and Microflex analysis with the matrix-assisted laser desorption ionization Biotyper systemQ33890222
Carbapenemase activity detection by matrix-assisted laser desorption ionization-time of flight mass spectrometryQ33966781
Using matrix-assisted laser desorption ionization-time of flight mass spectrometry to detect carbapenem resistance within 1 to 2.5 hours.Q33973352
Novel, improved sample preparation for rapid, direct identification from positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometryQ34010497
Evaluation of species-specific score cutoff values of routinely isolated clinically relevant bacteria using a direct smear preparation for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based bacterial identificationQ34030803
MALDI-TOF MS improves routine identification of non-fermenting Gram negative isolates from cystic fibrosis patientsQ34038965
Characterization of β-lactamase enzyme activity in bacterial lysates using MALDI-mass spectrometryQ34052356
A rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant EnterobacteriaceaeQ34058562
Impact of antimicrobial stewardship intervention on coagulase-negative Staphylococcus blood cultures in conjunction with rapid diagnostic testingQ34058641
An evaluation of three processing methods and the effect of reduced culture times for faster direct identification of pathogens from BacT/ALERT blood cultures by MALDI-TOF MS.Q34073607
Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratoriesQ34076344
Applications of MALDI-TOF mass spectrometry in clinical diagnostic microbiologyQ34076539
Distribution and regulation of the mobile genetic element-encoded phenol-soluble modulin PSM-mec in methicillin-resistant Staphylococcus aureusQ34103365
MALDI-TOF MS in microbiological diagnostics-identification of microorganisms and beyond (mini review).Q34111978
Comparison of the Microflex LT and Vitek MS systems for routine identification of bacteria by matrix-assisted laser desorption ionization-time of flight mass spectrometryQ34155689
The essence on mass spectrometry based microbial diagnosticsQ34191944
Evaluation of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of nonfermenting gram-negative bacilli isolated from cultures from cystic fibrosis patientsQ34229243
Detection of NDM-1, VIM-1, KPC, OXA-48, and OXA-162 carbapenemases by matrix-assisted laser desorption ionization-time of flight mass spectrometryQ34254372
Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for discrimination between molecular types of Cryptococcus neoformans and Cryptococcus gattiiQ34264267
Evaluation of the Andromas matrix-assisted laser desorption ionization-time of flight mass spectrometry system for identification of aerobically growing Gram-positive bacilli.Q34301924
Evaluation of species-specific score cut-off values for various Staphylococcus species using a MALDI Biotyper-based identificationQ34320800
Staphylococcus aureus bacteremia at 5 US academic medical centers, 2008-2011: significant geographic variation in community-onset infectionsQ34354252
Identification of blood culture isolates directly from positive blood cultures by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and a commercial extraction system: analysis of performance, cost, and turnaround tQ34372186
Impact of matrix-assisted laser desorption ionization time-of-flight mass spectrometry on the clinical management of patients with Gram-negative bacteremia: a prospective observational study.Q34522207
MALDI-TOF-MS-based species identification and typing approaches in medical mycology.Q34529370
The presence of a single MALDI-TOF mass spectral peak predicts methicillin resistance in staphylococciQ34538664
Identification of pathogenic microorganisms directly from positive blood vials by matrix-assisted laser desorption/ionization time of flight mass spectrometry.Q34554036
MALDI-TOF MS distinctly differentiates nontypable Haemophilus influenzae from Haemophilus haemolyticusQ34606554
Rapid identification and susceptibility testing of Candida spp. from positive blood cultures by combination of direct MALDI-TOF mass spectrometry and direct inoculation of Vitek 2.Q34663458
Rapid identification of pathogens directly from blood culture bottles by Bruker matrix-assisted laser desorption laser ionization-time of flight mass spectrometry versus routine methodsQ34751590
Characterization of Staphylococcus aureus isolated from clinical specimens by matrix assisted laser desorption/ionization time-of-flight mass spectrometryQ34788700
Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization-time of flight mass spectrometry analysisQ34793588
Rapid identification of Gram-negative organisms from blood culture bottles using a modified extraction method and MALDI-TOF mass spectrometryQ34869788
Comparison of matrix-assisted laser desorption ionization-time of flight (maldi-tof) mass spectrometry platforms for the identification of gram-negative rods from patients with cystic fibrosisQ34961425
Novel approach for differentiating Shigella species and Escherichia coli by matrix-assisted laser desorption ionization-time of flight mass spectrometryQ34975940
MALDI biotyper-based rapid resistance detection by stable-isotope labelingQ34978453
Advantages of using matrix-assisted laser desorption ionization-time of flight mass spectrometry as a rapid diagnostic tool for identification of yeasts and mycobacteria in the clinical microbiological laboratoryQ34992093
Comparison of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of mycobacteria using simplified protein extraction protocolsQ35028920
Evaluation of two matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of viridans group streptococci.Q35033780
Usefulness of matrix-assisted laser desorption ionisation-time-of-flight mass spectrometry for identifying clinical Trichosporon isolates.Q35071998
Differentiation of the emerging human pathogens Trichosporon asahii and Trichosporon asteroides from other pathogenic yeasts and moulds by using species-specific monoclonal antibodiesQ35083471
Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for rapid detection of β-lactam resistance in Enterobacteriaceae derived from blood culturesQ35084748
Automatic identification of mixed bacterial species fingerprints in a MALDI-TOF mass-spectrumQ35085770
Same day identification and full panel antimicrobial susceptibility testing of bacteria from positive blood culture bottles made possible by a combined lysis-filtration method with MALDI-TOF VITEK mass spectrometry and the VITEK2 systemQ35097287
Insufficient discriminatory power of MALDI-TOF mass spectrometry for typing of Enterococcus faecium and Staphylococcus aureus isolatesQ35116028
Comparative study of MALDI-TOF MS and VITEK 2 in bacteria identificationQ35167641
Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremiaQ35170970
MALDI-TOF: a useful tool for laboratory identification of uncommon glucose non-fermenting Gram-negative bacteria associated with cystic fibrosisQ35198600
Identification of filamentous fungi isolates by MALDI-TOF mass spectrometry: clinical evaluation of an extended reference spectra libraryQ35370259
Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of molds of the Fusarium genusQ35438499
Preliminary evidence for a serum disaccharide signature of invasive Candida albicans infection detected by MALDI Mass SpectrometryQ35552217
Assessment of Reproducibility of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Bacterial and Yeast IdentificationQ35618485
Rapid and reliable identification of Gram-negative bacteria and Gram-positive cocci by deposition of bacteria harvested from blood cultures onto the MALDI-TOF plateQ35666516
Detection of triazole resistance among Candida species by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS).Q35688413
A Side by Side Comparison of Bruker Biotyper and VITEK MS: Utility of MALDI-TOF MS Technology for Microorganism Identification in a Public Health Reference LaboratoryQ35867084
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)1097
P577publication date2018-05-29
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleRecent Advances and Ongoing Challenges in the Diagnosis of Microbial Infections by MALDI-TOF Mass Spectrometry
P478volume9