Discovery of a novel potent peptide agonist to adiponectin receptor 1.

scientific article published on 18 June 2018

Discovery of a novel potent peptide agonist to adiponectin receptor 1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0199256
P8608Fatcat IDrelease_5odomg7rqrgfnj3mbtqpwfuwmy
P932PMC publication ID6005460
P698PubMed publication ID29912982

P50authorYounho LeeQ59680293
Sunghwan KimQ89137604
P2093author name stringYoung-Jin Son
Dong Il Kim
Nam Doo Kim
Jee-Hyun Um
Min Jung Ma
Sang Hyun Min
Jun Woo Kim
Brian B Kim
P2860cites workActivation of Adiponectin Receptor Regulates Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Inhibits Lesions in ApoE-Deficient Mice.Q50862455
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actionsQ57249776
Improvement of oral peptide bioavailability: Peptidomimetics and prodrug strategiesQ73850235
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinaseQ24309462
Crystal structure of a single-chain trimer of human adiponectin globular domainQ27678213
Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor.Q27936252
The adipocyte-secreted protein Acrp30 enhances hepatic insulin actionQ28505765
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesityQ28506782
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndromeQ29619211
Design and development of a peptide-based adiponectin receptor agonist for cancer treatmentQ34040946
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in miceQ34118282
Development of second generation peptides modulating cellular adiponectin receptor responses.Q34360125
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesityQ34381237
Cell Biology. Ronning after the adiponectin receptorsQ34393247
The global implications of diabetes and cancerQ34423638
Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2Q35085549
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.Q35101294
Obesity-associated improvements in metabolic profile through expansion of adipose tissueQ35945161
Strategic approaches to optimizing peptide ADME propertiesQ38264736
A potent peptide as adiponectin receptor 1 agonist to against fibrosisQ38929057
Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.Q39720264
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivityQ40681900
Crystal structures of the human adiponectin receptorsQ41099333
Structural insights into adiponectin receptors suggest ceramidase activity.Q41232999
Optimization of protein production in mammalian cells with a coexpressed fluorescent markerQ45008634
PEGylation of octreotide: II. Effect of N-terminal mono-PEGylation on biological activity and pharmacokinetics.Q46500459
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)e0199256
P577publication date2018-06-18
P1433published inPLOS OneQ564954
P1476titleDiscovery of a novel potent peptide agonist to adiponectin receptor 1
P478volume13

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cites work (P2860)
Q92537528Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases
Q92921563Potential Adiponectin Receptor Response Modifier Therapeutics
Q64929242The Emerging Role of Adiponectin in Female Malignancies.