scholarly article | Q13442814 |
P8978 | DBLP publication ID | journals/ficn/HassanSSAZM18 |
P356 | DOI | 10.3389/FNCOM.2018.00034 |
P932 | PMC publication ID | 5992503 |
P698 | PubMed publication ID | 29910719 |
P50 | author | Ahmed Abdelhalim Moustafa | Q60496292 |
P2093 | author name string | Mubashir Hassan | |
Nazar Zaki | |||
Saba Shahzadi | |||
Hany Alashwal | |||
Sung Y Seo | |||
P2860 | cites work | Purification and cloning of amyloid precursor protein beta-secretase from human brain | Q22010914 |
MolProbity: all-atom structure validation for macromolecular crystallography | Q24649111 | ||
VADAR: a web server for quantitative evaluation of protein structure quality | Q24672199 | ||
Crystal structure of memapsin 2 (beta-secretase) in complex with an inhibitor OM00-3 | Q27639565 | ||
PRODRG: a tool for high-throughput crystallography of protein-ligand complexes | Q27860633 | ||
Structure validation by Calpha geometry: phi,psi and Cbeta deviation | Q27860657 | ||
UCSF Chimera--a visualization system for exploratory research and analysis | Q27860666 | ||
LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions | Q27861128 | ||
Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery | Q28732740 | ||
Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties | Q28842810 | ||
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility | Q29547658 | ||
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit | Q29615867 | ||
AZD3293: Pharmacokinetic and Pharmacodynamic Effects in Healthy Subjects and Patients with Alzheimer's Disease. | Q51371177 | ||
Optimizing working parameters of the smooth particle mesh Ewald algorithm in terms of accuracy and efficiency. | Q51677593 | ||
An improved united atom force field for simulation of mixed lipid bilayers. | Q51798189 | ||
Safety and biomarker effects of solanezumab in patients with Alzheimer's disease. | Q53158136 | ||
Molecular dynamics studies of AChBP with nicotine and carbamylcholine: the role of water in the binding pocket | Q80535691 | ||
Online interactive analysis of protein structure ensembles with Bio3D-web | Q30390617 | ||
Automated minimization of steric clashes in protein structures | Q30395997 | ||
Pharmacoinformatics exploration of polyphenol oxidases leading to novel inhibitors by virtual screening and molecular dynamic simulation study | Q30400300 | ||
The emerging importance of predictive ADME simulation in drug discovery | Q31034745 | ||
In silico design of BACE1 inhibitor for Alzheimer's disease by traditional Chinese medicine. | Q33666808 | ||
Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease. | Q33946695 | ||
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study | Q34332159 | ||
Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target? | Q34419108 | ||
Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies | Q34472054 | ||
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures. | Q35599192 | ||
A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid β Aggregates | Q36754686 | ||
Automated docking with protein flexibility in the design of femtomolar "click chemistry" inhibitors of acetylcholinesterase | Q36974755 | ||
The role of metals in modulating metalloprotease activity in the AD brain. | Q37083267 | ||
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease | Q37118356 | ||
The structural evolution of β-secretase inhibitors: a focus on the development of small-molecule inhibitors | Q38127826 | ||
The evolution of amidine-based brain penetrant BACE1 inhibitors | Q38202365 | ||
BACE1 inhibitor drugs in clinical trials for Alzheimer's disease | Q38332419 | ||
The application of in silico drug-likeness predictions in pharmaceutical research | Q38349635 | ||
Exploration of Novel Human Tyrosinase Inhibitors by Molecular Modeling, Docking and Simulation Studies. | Q39835668 | ||
Rapid Characterization of Allosteric Networks with Ensemble Normal Mode Analysis | Q41361764 | ||
Molecular properties prediction, synthesis and antimicrobial activity of some newer oxadiazole derivatives | Q42851104 | ||
Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β. | Q46423931 | ||
Finding novel anti-carcinomas compounds by targeting SFRP4 through molecular modeling, docking and dynamic simulation studies. | Q47865009 | ||
Asp32 and Asp228 determine the selective inhibition of BACE1 as shown by docking and molecular dynamics simulations. | Q50226373 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P304 | page(s) | 34 | |
P577 | publication date | 2018-06-01 | |
P1433 | published in | Frontiers in Computational Neuroscience | Q15817583 |
P1476 | title | Molecular Docking and Dynamic Simulation of AZD3293 and Solanezumab Effects Against BACE1 to Treat Alzheimer's Disease. | |
P478 | volume | 12 |
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