miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT.

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miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1103389816
P356DOI10.1186/S12964-018-0228-Z
P932PMC publication ID5902930
P698PubMed publication ID29661252

P50authorYaqi DuanQ88374825
P2093author name stringYu Wang
Jun Li
Xiaoyan Wang
Henghui Cheng
Guoping Wang
Yaobing Chen
Qiu Zhao
Sanpeng Xu
Dong Kuang
Yuanli Zhu
P2860cites workPost-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]Q21133528
Gene ontology: tool for the unification of biologyQ23781406
KEGG: kyoto encyclopedia of genes and genomesQ24515297
Cytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Gastrointestinal stromal tumour.Q51037108
MicroRNA expression profile of gastrointestinal stromal tumors is distinguished by 14q loss and anatomic site.Q51563333
Differential expression of neural markers in KIT and PDGFRA wild-type gastrointestinal stromal tumours.Q54333730
MicroRNA expression profiles classify human cancersQ28032481
miR-148b functions as a tumor suppressor in non-small cell lung cancer by targeting carcinoembryonic antigen (CEA)Q28394161
SDHA loss-of-function mutations in KIT-PDGFRA wild-type gastrointestinal stromal tumors identified by massively parallel sequencingQ30401988
Down-regulation of miR-221 and miR-222 correlates with pronounced Kit expression in gastrointestinal stromal tumorsQ34153432
Circulating miR-148b and miR-133a as biomarkers for breast cancer detectionQ34221705
Gastrointestinal stromal tumors: molecular markers and genetic subtypes.Q34375253
MicroRNAs in cell proliferation, cell death, and tumorigenesis.Q34497050
MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferationQ34506870
Correlation of KIT and platelet-derived growth factor receptor alpha mutations with gene activation and expression profiles in gastrointestinal stromal tumorsQ34554769
Gene expression patterns of hemizygous and heterozygous KIT mutations suggest distinct oncogenic pathways: a study in NIH3T3 cell lines and GIST samplesQ34674610
Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31.Q35004231
MicroRNA functions in animal development and human diseaseQ36285673
MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumoursQ37182248
Loss of post-transcriptional regulation of DNMT3b by microRNAs: a possible molecular mechanism for the hypermethylation defect observed in a subset of breast cancer cell linesQ37696405
MicroRNA involvement in gastrointestinal stromal tumor tumorigenesisQ38054880
Exploring novel therapeutic targets in GIST: focus on the PI3K/Akt/mTOR pathwayQ38100719
An overview on molecular biology of KIT/PDGFRA wild type (WT) gastrointestinal stromal tumours (GIST).Q38119931
miRNA profiling in gastrointestinal stromal tumors: implication as diagnostic and prognostic markersQ38602174
miR-148b reverses cisplatin-resistance in non-small cell cancer cells via negatively regulating DNA (cytosine-5)-methyltransferase 1(DNMT1) expressionQ38880588
miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumoursQ38883917
FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors.Q38910534
Frequent mono-allelic loss associated with deficient PTEN expression in imatinib-resistant gastrointestinal stromal tumorsQ39003171
MicroRNA-494 downregulates KIT and inhibits gastrointestinal stromal tumor cell proliferationQ39449811
MicroRNAs and cancer: short RNAs go a long way.Q41906288
Insulin-like growth factor 1 receptor expression in wild-type GISTs: a potential novel therapeutic target.Q43293512
KIT activation is a ubiquitous feature of gastrointestinal stromal tumorsQ43806543
miR-148b functions as a tumor suppressor in pancreatic cancer by targeting AMPKα1.Q44213136
MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer.Q45358026
MicroRNA-218 inhibits gastrointestinal stromal tumor cell and invasion by targeting KIT.Q45736946
Role of PTEN in gastrointestinal stromal tumor progressionQ47886024
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P433issue1
P304page(s)16
P577publication date2018-04-16
P1433published inCell Communication and SignalingQ1254390
P1476titlemiR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT
P478volume16

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cites work (P2860)
Q91272122MicroRNA-148a/b-3p regulates angiogenesis by targeting neuropilin-1 in endothelial cells
Q92713862Signatures of circulating microRNA in four sarcoma subtypes
Q93091136Whey Protein Supplementation Post Resistance Exercise in Elderly Men Induces Changes in Muscle miRNA's Compared to Resistance Exercise Alone

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