NF-κB signaling and its relevance to the treatment of mantle cell lymphoma.

scientific article

NF-κB signaling and its relevance to the treatment of mantle cell lymphoma. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1104647446
P356DOI10.1186/S13045-018-0621-5
P932PMC publication ID6002979
P698PubMed publication ID29907126

P2093author name stringMichael Wang
Krystle Nomie
Makhdum Ahmed
Swathi Balaji
Fangfang Yan
Elizabeth Lorence
P2860cites workThe interaction of p62 with RIP links the atypical PKCs to NF-kappaB activationQ22009927
Src-family kinases in B-cell development and signalingQ24307580
BLNK: a central linker protein in B cell activationQ24322718
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complexQ24329065
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphomaQ24613755
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancyQ24633214
Regulation of transient receptor potential channels by the phospholipase C pathwayQ26822505
Mesalamine in the treatment and maintenance of remission of ulcerative colitisQ26865546
Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinasesQ27658863
Targeting protein kinase C in mantle cell lymphomaQ38791124
Concomitant high expression of Toll-like receptor (TLR) and B-cell receptor (BCR) signalling molecules has clinical implications in mantle cell lymphomaQ38965699
Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphomaQ39040982
Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-{kappa}B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis.Q40467188
An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway.Q40472871
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradationQ40566781
Serine 32 and serine 36 of IkappaBalpha are directly phosphorylated by protein kinase CKII in vitroQ42474454
The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic targetQ42524101
Possible new role for NF-kappaB in the resolution of inflammation.Q43811439
The Bruton tyrosine kinase inhibitor CC-292 shows activity in mantle cell lymphoma and synergizes with lenalidomide and NIK inhibitors depending on nuclear factor-κB mutational statusQ45594007
Essential role of MD-2 in LPS responsiveness and TLR4 distributionQ50109313
BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.Q53664665
Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways.Q54648964
Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial.Q54986442
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signalingQ56897808
Unlocking New Therapeutic Targets and Resistance Mechanisms in Mantle Cell LymphomaQ57279270
Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaBQ64381570
B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotidesQ81474815
Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemiaQ27824808
Ibrutinib in previously treated Waldenström's macroglobulinemia.Q27853148
Acalabrutinib (ACP-196): a selective second-generation BTK inhibitorQ28066316
Second-generation inhibitors of Bruton tyrosine kinaseQ28076118
Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100Q28216699
B-cell receptor signalling and its crosstalk with other pathways in normal and malignant cellsQ28245018
Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphomaQ28263800
BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2Q28589369
Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphomaQ30371806
Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas.Q30375911
Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphomaQ33372761
Idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase-δ, as therapy for previously treated indolent non-Hodgkin lymphomaQ33413834
Lenalidomide plus Rituximab as Initial Treatment for Mantle-Cell LymphomaQ33427312
NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphomaQ33878632
Activation of NF-kappaB by FADD, Casper, and caspase-8.Q33897301
Do mantle cell lymphomas have an 'Achilles heel'?Q34090009
Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB.Q34101051
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epitheliumQ34202130
Toll-like receptor-4 signaling in mantle cell lymphoma: effects on tumor growth and immune evasionQ34415459
A phase 1 study of the PI3Kδ inhibitor idelalisib in patients with relapsed/refractory mantle cell lymphoma (MCL).Q34663617
NF-κB signaling pathways regulated by CARMA family of scaffold proteinsQ35347919
Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activitiesQ35849327
Toll-Like Receptor 1/2 and 5 Ligands Enhance the Expression of Cyclin D1 and D3 and Induce Proliferation in Mantle Cell Lymphoma.Q36001708
FNC efficiently inhibits mantle cell lymphoma growthQ36319779
Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cellsQ36369816
Lymphomagenic CARD11/BCL10/MALT1 signaling drives malignant B-cell proliferation via cooperative NF-κB and JNK activationQ36435313
The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinaseQ37057476
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphomaQ37076425
Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4.Q37158116
Akt-mediated regulation of NFkappaB and the essentialness of NFkappaB for the oncogenicity of PI3K and AktQ37399825
MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.Q37433320
Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism.Q37706550
Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFalpha/NF-kappaB signaling axisQ38343572
TG2 and NF-κB Signaling Coordinates the Survival of Mantle Cell Lymphoma Cells via IL6-Mediated AutophagyQ38734433
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P433issue1
P921main subjectmantle cell lymphomaQ268713
transcription factorQ407384
NF-κBQ411114
signal transductionQ828130
DNA-binding proteinQ2252764
nuclear proteinQ16860021
P304page(s)83
P577publication date2018-06-15
P1433published inJournal of Hematology & OncologyQ15724593
P1476titleNF-κB signaling and its relevance to the treatment of mantle cell lymphoma.
P478volume11

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cites work (P2860)
Q92271274A novel specific cleavage of IκBα protein in acute myeloid leukemia cells involves protease PR3
Q91627122Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy
Q102071906Expression and role of MIG/CXCR3 axis in mantle cell lymphoma
Q61805953Mantle cell lymphoma and its management: where are we now?
Q99622777Molecular Pathogenesis of Mantle Cell Lymphoma
Q92647353Novel immunomodulatory drugs and neo-substrates
Q99710790PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers
Q92568405SP/NK-1R promotes gallbladder cancer cell proliferation and migration
Q97593212Targeting CD83 in mantle cell lymphoma with anti-human CD83 antibody
Q91660586Targeting mTOR for cancer therapy
Q92211257The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB-Inducing Kinase

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