| P50 | author | Louis S Ates | Q58803106 |
| | Merel Pm Damen | Q88885475 |
| | Fadel Sayes | Q89531901 |
| | Roland Brosch | Q55345261 |
| | Wilbert Bitter | Q57423000 |
| P2093 | author name string | Marcel A Behr | |
| | Daria Bottai | |
| | Wafa Frigui | |
| | Roy Ummels | |
| | Laleh Majlessi | |
| | Jeroen W J van Heijst | |
| P2860 | cites work | Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis | Q57984777 |
| | M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells | Q59498046 |
| | Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 ofMycobacterium tuberculosis | Q60920169 |
| | PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5 | Q61400121 |
| | A specific secretion system mediates PPE41 transport in pathogenic mycobacteria | Q63359646 |
| | Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family | Q73827310 |
| | Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence | Q22122411 |
| | A new evolutionary scenario for the Mycobacterium tuberculosis complex | Q24531514 |
| | Genome plasticity of BCG and impact on vaccine efficacy | Q24674276 |
| | TB vaccine development and the End TB Strategy: importance and current status. | Q26748621 |
| | CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection | Q27312482 |
| | The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10 | Q27313551 |
| | Portrait of a pathogen: the Mycobacterium tuberculosis proteome in vivo | Q28476108 |
| | Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP | Q28486372 |
| | Phospholipases C are involved in the virulence of Mycobacterium tuberculosis | Q28486439 |
| | A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis | Q28487314 |
| | Co-evolution of Mycobacterium tuberculosis and Homo sapiens | Q28649483 |
| | NCBI BLAST: a better web interface | Q29614461 |
| | Mycobacterial PE/PPE proteins at the host-pathogen interface | Q30399629 |
| | Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays | Q30697305 |
| | Survival of mice infected with Mycobacterium smegmatis containing large DNA fragments from Mycobacterium tuberculosis | Q30836037 |
| | Expression cloning of an immunodominant family of Mycobacterium tuberculosis antigens using human CD4(+) T cells | Q30837139 |
| | Genetic toggling of alkaline phosphatase folding reveals signal peptides for all major modes of transport across the inner membrane of bacteria | Q30848105 |
| | Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions | Q33263607 |
| | Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region | Q33505452 |
| | PE_PGRS antigens of Mycobacterium tuberculosis induce maturation and activation of human dendritic cells. | Q51855407 |
| | New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages. | Q52323561 |
| | Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors. | Q52563498 |
| | A historical and molecular phylogeny of BCG strains. | Q53557023 |
| | Multiple, independent, identical IS6110 insertions in Mycobacterium tuberculosis PPE genes | Q57385421 |
| | Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense | Q33600855 |
| | The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection | Q33603832 |
| | Deciphering the role of IS6110 in a highly transmissible Mycobacterium tuberculosis Beijing strain, GC1237. | Q33800256 |
| | Comparative immune response to PE and PE_PGRS antigens of Mycobacterium tuberculosis. | Q34008969 |
| | Revisiting the evolution of Mycobacterium bovis | Q34048389 |
| | Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant | Q34132063 |
| | Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints | Q34229760 |
| | Characterization of Mycobacterium orygis as M. tuberculosis complex subspecies | Q34265268 |
| | Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence | Q34300954 |
| | Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis | Q34527217 |
| | The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability | Q34532886 |
| | Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset | Q34566079 |
| | The PE multigene family: a 'molecular mantra' for mycobacteria | Q34612597 |
| | Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway | Q34998258 |
| | Modeling bacterial evolution with comparative-genome-based marker systems: application to Mycobacterium tuberculosis evolution and pathogenesis | Q35006529 |
| | Comparing genomes within the species Mycobacterium tuberculosis | Q35033207 |
| | A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis | Q35033838 |
| | Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage | Q35544538 |
| | IS6110 mediates increased transcription of the phoP virulence gene in a multidrug-resistant clinical isolate responsible for tuberculosis outbreaks | Q35551848 |
| | Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo | Q35556626 |
| | Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria | Q35566537 |
| | Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis | Q35603209 |
| | Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death | Q35728994 |
| | Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations | Q36187495 |
| | Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis | Q36316419 |
| | Preventive Vaccination Against Tuberculosis with BCG. | Q36337757 |
| | The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue | Q36350501 |
| | Precision methylome characterization of Mycobacterium tuberculosis complex (MTBC) using PacBio single-molecule real-time (SMRT) technology | Q36532705 |
| | Protection and Long-Lived Immunity Induced by the ID93/GLA-SE Vaccine Candidate against a Clinical Mycobacterium tuberculosis Isolate | Q36555077 |
| | Vaccine-elicited 10-kilodalton culture filtrate protein-specific CD8+ T cells are sufficient to mediate protection against Mycobacterium tuberculosis infection | Q36593990 |
| | Conditionally replicating mycobacteriophages: a system for transposon delivery to Mycobacterium tuberculosis | Q36603027 |
| | Comparison of Mycobacterium tuberculosis genomes reveals frequent deletions in a 20 kb variable region in clinical isolates | Q36750457 |
| | Identification of human T cell antigens for the development of vaccines against Mycobacterium tuberculosis | Q36982831 |
| | Novel Mycobacterium tuberculosis complex isolate from a wild chimpanzee | Q37020490 |
| | Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria | Q37258663 |
| | Strong antibody responses to Mycobacterium tuberculosis PE-PGRS62 protein are associated with latent and active tuberculosis. | Q37274903 |
| | Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis | Q37377646 |
| | Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognition | Q37519858 |
| | PPE38 Protein of Mycobacterium tuberculosis Inhibits Macrophage MHC Class I Expression and Dampens CD8+ T Cell Responses | Q37694483 |
| | Fact and fiction in tuberculosis vaccine research: 10 years later | Q37907518 |
| | Getting across the cell envelope: mycobacterial protein secretion | Q38067334 |
| | Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity. | Q38366403 |
| | PE_PGRS30 of Mycobacterium tuberculosis mediates suppression of proinflammatory immune response in macrophages through its PGRS and PE domains | Q38774396 |
| | ESX secretion systems: mycobacterial evolution to counter host immunity | Q38963878 |
| | Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study | Q38971924 |
| | The Enigmatic PE/PPE Multigene Family of Mycobacteria and Tuberculosis Vaccination | Q39203406 |
| | ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria | Q39360723 |
| | Protective vaccine efficacy of the complete form of PPE39 protein from Mycobacterium tuberculosis Beijing/K strain in mice | Q40064027 |
| | Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection | Q40292960 |
| | Genomic interrogation of the dassie bacillus reveals it as a unique RD1 mutant within the Mycobacterium tuberculosis complex | Q40377422 |
| | pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence | Q40559589 |
| | Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47. | Q40562830 |
| | The Type of Growth Medium Affects the Presence of a Mycobacterial Capsule and Is Associated With Differences in Protective Efficacy of BCG Vaccination Against Mycobacterium tuberculosis | Q40656117 |
| | XDR-TB transmission in London: Case management and contact tracing investigation assisted by early whole genome sequencing. | Q40696792 |
| | Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis | Q41077364 |
| | What Have We Learnt about BCG Vaccination in the Last 20 Years? | Q41684091 |
| | Key epitopes on the ESAT-6 antigen recognized in mice during the recall of protective immunity to Mycobacterium tuberculosis. | Q42641411 |
| | Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system | Q43405268 |
| | The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes | Q43746791 |
| | Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti | Q44056191 |
| | Composition of the type VII secretion system membrane complex. | Q45296085 |
| | Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential | Q45855190 |
| | Whole genome sequence analysis of Mycobacterium suricattae. | Q46260114 |
| | Mycobacterium tuberculosis Complex Members Adapted to Wild and Domestic Animals | Q46265783 |
| | The pyruvate requirement of some members of the Mycobacterium tuberculosis complex is due to an inactive pyruvate kinase: implications for in vivo growth | Q46386676 |
| | Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation | Q46837987 |
| | Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials | Q46851619 |
| | Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis | Q48239743 |
| | Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis. | Q48297230 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 6 | |
| P921 | main subject | BCG vaccine | Q798309 |
| P304 | page(s) | e1007139 | |
| P577 | publication date | 2018-06-18 | |
| P1433 | published in | PLOS Pathogens | Q283209 |
| P1476 | title | RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection. | |
| P478 | volume | 14 | |