Treating p53 Mutant Aggregation-Associated Cancer.

scientific article published on 23 May 2018

Treating p53 Mutant Aggregation-Associated Cancer. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/CANCERS10060154
P932PMC publication ID6025594
P698PubMed publication ID29789497

P2093author name stringMathumai Kanapathipillai
P2860cites workPolyarginine and its analogues inhibit p53 mutant aggregation and cancer cell proliferation in vitro.Q50865600
Immunoexpression of tumor suppressor genes p53, p21 WAF1/CIP1 and p27 KIP1 in humam astrocystic tumors.Q55466958
Gain of function of mutant p53 by coaggregation with multiple tumor suppressorsQ57670523
Role of acetylcholinesterase in lung cancerQ26798216
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The rebel angel: mutant p53 as the driving oncogene in breast cancerQ27686765
Surfing the p53 networkQ28032484
Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's beta-amyloidQ28267119
The p53 pathway: positive and negative feedback loopsQ29617535
Inhibition of protein aggregation: supramolecular assemblies of arginine hold the keyQ33305439
p53 and apoptosisQ33547818
Targeting p53 for Novel Anticancer TherapyQ33655329
Twenty years of p53 research: structural and functional aspects of the p53 proteinQ33807787
Mutant p53: one name, many proteinsQ36070574
Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.Q36201740
A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian CarcinomasQ36521889
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Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.Q36710840
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Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancerQ36876885
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Amyloidogenicity of p53: a hidden link between protein misfolding and cancerQ38360401
Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.Q38723653
p21: A Two-Faced Genome Guardian.Q38747952
Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity.Q39222212
Small stress molecules inhibit aggregation and neurotoxicity of prion peptide 106-126.Q40044593
p53 Aggregates penetrate cells and induce the co-aggregation of intracellular p53.Q42255562
The threads that tie protein-folding diseasesQ42728659
The effects of arginine on refolding of aggregated proteins: not facilitate refolding, but suppress aggregationQ44410263
Fibrillar aggregates of the tumor suppressor p53 core domainQ44528743
Inhibition of insulin amyloid formation by small stress moleculesQ44849270
Role of arginine in the stabilization of proteins against aggregationQ46393024
Inhibition of beta-amyloid peptide aggregation and neurotoxicity by alpha-d-mannosylglycerate, a natural extremolyteQ46730195
Monoclonal Antibodies against Specific p53 Hotspot Mutants as Potential Tools for Precision MedicineQ47214007
Mutant p53 as a target for cancer treatment.Q48012976
Inhibition of p53 Mutant Peptide Aggregation In Vitro by Cationic Osmolyte Acetylcholine ChlorideQ50218287
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P577publication date2018-05-23
P1433published inCancersQ27722963
P1476titleTreating p53 Mutant Aggregation-Associated Cancer.
P478volume10

Reverse relations

cites work (P2860)
Q89703505Bifunctional ligand design for modulating mutant p53 aggregation in cancer
Q64113644p53 Signaling in Cancers

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