Pharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases.

scientific article published on 21 October 2017

Pharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JGR.2017.10.004
P932PMC publication ID6026386
P698PubMed publication ID29983607

P2093author name stringJong-Hoon Kim
P2860cites workNitric oxide: physiology, pathophysiology, and pharmacologyQ26778243
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An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes.Q37576766
Anti-hypoxic effect of ginsenoside Rbl on neonatal rat cardiomyocytes is mediated through the specific activation of glucose transporter-4 ex vivoQ39010661
Ginsenoside-Rd, a purified component from panax notoginseng saponins, prevents atherosclerosis in apoE knockout miceQ39625234
The phytoestrogen ginsensoside Re activates potassium channels of vascular smooth muscle cells through PI3K/Akt and nitric oxide pathwaysQ40078895
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Nitric oxide-dependent modulation of the delayed rectifier K+ current and the L-type Ca2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytesQ41973156
Making a case for quantitative assessment of cardiovascular riskQ42752792
Total ginsenosides increase coronary perfusion flow in isolated rat hearts through activation of PI3K/Akt-eNOS signalingQ42932047
Ginsenoside Rb3 inhibits angiotensin II-induced vascular smooth muscle cells proliferationQ42956312
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Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunitQ43095418
The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heartQ43114540
Effects of Korean red ginseng (Panax ginseng C.A. Mayer) and its isolated ginsenosides and polysaccharides on arterial stiffness in healthy individualsQ43172307
Interaction between warfarin and Korean red ginseng in patients with cardiac valve replacementQ43242457
Superoxide dismutase 10 years later: a drug in search of a use.Q43845096
Electrophysiological effects of ginseng and ginsenoside Re in guinea pig ventricular myocytesQ44582035
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Mutations Leu427, Asn428, and Leu431 residues within transmembrane domain-I-segment 6 attenuate ginsenoside-mediated L-type Ca(2+) channel current inhibitions.Q45943178
Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis.Q45967691
Improving effect of post-treatment with Panax notoginseng saponins on lipopolysaccharide-induced microcirculatory disturbance in rat mesentery.Q46231141
Inhibitory mechanisms of dihydroginsenoside Rg3 in platelet aggregation: critical roles of ERK2 and cAMP.Q46289411
Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytesQ46447472
Relaxation of canine corporal smooth muscle relaxation by ginsenoside saponin Rg3 is independent from eNOS activationQ46452292
Total ginsenosides inhibit the right ventricular hypertrophy induced by monocrotaline in rats.Q46453049
Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteriesQ46484646
Korean red ginseng attenuates hypercholesterolemia-enhanced platelet aggregation through suppression of diacylglycerol liberation in high-cholesterol-diet-fed rabbitsQ46618939
Panax ginseng reduces adriamycin-induced heart failure in ratsQ46863970
Bifidus fermentation increases hypolipidemic and hypoglycemic effects of red ginseng.Q46872976
Antioxidant effects of ginsenoside Re in cardiomyocytes.Q46959893
Effects of ginsenosides and their metabolites on voltage-dependent Ca(2+) channel subtypes.Q46971409
Ginsenosides compound K and Rh(2) inhibit tumor necrosis factor-alpha-induced activation of the NF-kappaB and JNK pathways in human astroglial cellsQ48147335
Ginsenoside Rb1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathwayQ48473872
Anti-lipid peroxilative effect of ginsenoside Rb1 and Rg1.Q48730502
Effect of Korean red ginseng on arterial stiffness in subjects with hypertension.Q50548689
Red ginseng extract improves coronary flow reserve and increases absolute numbers of various circulating angiogenic cells in patients with first ST-segment elevation acute myocardial infarction.Q50569523
Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells.Q50677677
Antithrombotic and antiplatelet activities of Korean red ginseng extract.Q50704668
Total panax notoginsenosides prevent atherosclerosis in apolipoprotein E-knockout mice: Role of downregulation of CD40 and MMP-9 expression.Q53375844
Effects of extracts from Panax notoginseng and Panax ginseng fruit on vascular endothelial cell proliferation and migration in vitro.Q53470490
Protective effects of ginsenoside Rb1 on human umbilical vein endothelial cells in vitro.Q53526848
Effect of Korea red ginseng on the blood pressure in conscious hypertensive rats.Q53676429
Ginseng protects rodent hearts from acute myocardial ischemia-reperfusion injury through GR/ER-activated RISK pathway in an endothelial NOS-dependent mechanism.Q54605051
Protective effect of ginsenoside Rb1 against myocardial ischemia/reperfusion injury in streptozotocin-induced diabetic ratsQ54630124
Ginsenoside Rg3 increases nitric oxide production via increases in phosphorylation and expression of endothelial nitric oxide synthase: essential roles of estrogen receptor-dependent PI3-kinase and AMP-activated protein kinase.Q54667707
Panax ginseng Administration in the Rat Prevents Myocardial Ischemia-Reperfusion Damage Induced by Hyperbaric Oxygen: Evidence for an Antioxidant InterventionQ59195748
Ginsenoside Re, a Main Phytosterol of Panax ginseng, Activates Cardiac Potassium Channels via a Nongenomic Pathway of Sex HormonesQ59767172
The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosisQ71605264
Ginseng extract scavenges hydroxyl radical and protects unsaturated fatty acids from decomposition caused by iron-mediated lipid peroxidationQ71749370
Effect of ginsenoside Re on the electrophysiological activity of the heartQ72511443
Improved isolated heart contractility and mitochondrial oxidation after chronic treatment with Panax ginseng in ratsQ72582460
Steaming of ginseng at high temperature enhances biological activityQ73352506
Liquid chromatographic determination of less polar ginsenosides in processed ginsengQ74261693
Ginsenoside Rf2, a new dammarane glycoside from Korean red ginseng (Panax ginseng)Q77754108
116 cases of coronary angina pectoris treated with powder composed of radix ginseng, radix notoginseng and succinumQ78098194
Signaling pathway of nitric oxide production induced by ginsenoside Rb1 in human aortic endothelial cells: a possible involvement of androgen receptorQ79464774
Shenfu injection suppresses apoptosis by regulation of Bcl-2 and caspase-3 during hypoxia/reoxygenation in neonatal rat cardiomyocytes in vitroQ80122629
Inhibitory effect of ginsenoside Rb1 on calcineurin signal pathway in cardiomyocyte hypertrophy induced by prostaglandin F2alphaQ80640140
Act local, act global: inflammation and the multiplicity of "vulnerable" coronary plaquesQ81746585
Signaling pathway of ginsenoside-Rg1 leading to nitric oxide production in endothelial cellsQ83333509
Compound K, a metabolite of ginsenosides, induces cardiac protection mediated nitric oxide via Akt/PI3K pathwayQ83455115
Panax notoginseng reduces atherosclerotic lesions in ApoE-deficient mice and inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesionQ84504080
Saponins of red ginseng.Q115949427
P433issue3
P921main subjectPanax ginsengQ182881
cardiovascular diseaseQ389735
P304page(s)264-269
P577publication date2017-10-21
P1433published inJournal of Ginseng ResearchQ26841821
P1476titlePharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases.
P478volume42

Reverse relations

cites work (P2860)
Q89867799Anti-platelet role of Korean ginseng and ginsenosides in cardiovascular diseases
Q98613063Aquaporin 7 involved in GINSENOSIDE-RB1-mediated anti-obesity via peroxisome proliferator-activated receptor gamma pathway
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Q64093688Efficacy and Mechanism of Panax Ginseng in Experimental Stroke
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Q91972929Ginsenoside-Rb1 for Ischemic Stroke: A Systematic Review and Meta-analysis of Preclinical Evidence and Possible Mechanisms
Q89522192Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling
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Q64103615Phytochemicals Targeting VEGF and VEGF-Related Multifactors as Anticancer Therapy
Q90397394Pro-Resolving Effect of Ginsenosides as an Anti-Inflammatory Mechanism of Panax ginseng
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Q90599824Rumex acetosa modulates platelet function and inhibits thrombus formation in rats
Q57214573Seasonal Variation and Possible Biosynthetic Pathway of Ginsenosides in Korean Ginseng Meyer
Q91723084Selection and validation of reference genes desirable for gene expression analysis by qRT-PCR in MeJA-treated ginseng hairy roots

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