Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men

scientific article published on 10 February 2014

Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JPHYSIOL.2013.270256
P932PMC publication ID4001758
P698PubMed publication ID24514907
P5875ResearchGate publication ID260153385

P50authorJes OlesenQ29643374
Henriette PilegaardQ37375640
Lasse GliemannQ38545369
Ylva HellstenQ41685910
P2093author name stringJakob Schmidt
Rasmus Biensø
P2860cites workMultiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twinsQ24561604
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous miceQ24597354
Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous miceQ24604312
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterasesQ24608197
Antioxidants prevent health-promoting effects of physical exercise in humansQ24646248
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life spanQ24649811
Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscleQ24657207
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Resveratrol improves health and survival of mice on a high-calorie dietQ27860950
Transcriptional regulation of gene expression in human skeletal muscle during recovery from exerciseQ28139373
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanQ28203572
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alphaQ28274682
Strength conditioning in older men: skeletal muscle hypertrophy and improved functionQ28297121
Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged miceQ28390560
Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluationQ28534558
Sirtuin activators mimic caloric restriction and delay ageing in metazoansQ29547766
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibresQ29555845
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null miceQ29614547
PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscleQ30426890
Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese HumansQ32774312
AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrolQ33688533
Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammationQ33710086
Reactive oxygen species enhance insulin sensitivityQ33941647
Percutaneous needle biopsy of skeletal muscle in physiological and clinical researchQ34084383
Exercise, inflammation and agingQ34268096
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial functionQ34272924
Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidationQ34515904
Resveratrol, a phenolic antioxidant with effects on blood platelet functionsQ34559219
Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.Q34701848
Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance.Q34733232
Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose toleranceQ35123509
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalkQ36025294
Evidence for prescribing exercise as therapy in chronic diseaseQ36383909
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose toleranceQ36392797
High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.Q36720635
Pilot study of resveratrol in older adults with impaired glucose tolerance.Q36895103
The role of exercise and PGC1alpha in inflammation and chronic diseaseQ36984669
Physical activity and the elderlyQ37016909
Bioavailability of resveratrolQ37831925
Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesisQ39208622
Enzyme patterns in single human muscle fibersQ39866920
Time Course of Changes in Human Skeletal Muscle Succinate Dehydrogenase and Cytochrome Oxidase Activities and Maximal Oxygen Uptake with Physical Activity and InactivityQ40054745
Mitochondrial function and apoptotic susceptibility in aging skeletal muscleQ42521646
Acute exposure to resveratrol inhibits AMPK activity in human skeletal muscle cellsQ42716472
Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants.Q43040907
Relative workload determines exercise-induced increases in PGC-1alpha mRNA.Q43169879
PGC-1alpha is required for training-induced prevention of age-associated decline in mitochondrial enzymes in mouse skeletal muscleQ43189781
Improved insulin sensitivity after weight loss and exercise training is mediated by a reduction in plasma fatty acid mobilization, not enhanced oxidative capacityQ43282332
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.Q44240302
Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacityQ44527020
Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle.Q44666324
Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men.Q46587342
PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle.Q46855461
A role for the transcriptional coactivator PGC-1alpha in muscle refuelingQ46954472
Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise trainingQ46966530
Gene expression in human skeletal muscle: alternative normalization method and effect of repeated biopsies.Q51358089
Mitochondrial biogenesis and angiogenesis in skeletal muscle of the elderly.Q54377148
Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α.Q54411752
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.Q54606528
The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of diseaseQ58466366
Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cellsQ64377356
Effects of 8 weeks' endurance training on skeletal muscle metabolism in 56-70-year-old sedentary menQ67694641
Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscleQ68565257
Effect of training on enzyme activity and fiber composition of human skeletal muscleQ68658942
Oxidative capacity and ageing in human muscleQ73948206
Resveratrol has no effect on lipoprotein profile and does not prevent peroxidation of serum lipids in normal ratsQ74141587
The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmfulQ77584639
Physiology of agingQ77826592
Predominant alpha2/beta2/gamma3 AMPK activation during exercise in human skeletal muscleQ79233726
Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in ratsQ83803005
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)1873-1886
P577publication date2014-02-10
P1433published inJournal of PhysiologyQ7743612
P1476titleExercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men
P478volume592

Reverse relations

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