scholarly article | Q13442814 |
P50 | author | Yves-Alain Barde | Q30106726 |
Nicholas Allen | Q58887759 | ||
Pedro Chacón-Fernández | Q89046192 | ||
Nicholas C Wu | Q39722696 | ||
Xinsheng Nan | Q40991312 | ||
P2093 | author name string | Meng Li | |
Peter S DiStefano | |||
Richard A Lerner | |||
Jia Xie | |||
Geramie Grande | |||
Chih-Wei Lin | |||
Alexey V Stepanov | |||
Kate E Binley | |||
Ronald M Lindsay | |||
Spyros Merkouris | |||
P2860 | cites work | A de novo mutation affecting human TrkB associated with severe obesity and developmental delay | Q24307838 |
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Identification of a novel mutation in the NTF4 gene that causes primary open-angle glaucoma in a Chinese population | Q24628693 | ||
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis | Q24651301 | ||
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma | Q24657994 | ||
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Recent advances in the development of anti-HER2 antibodies and antibody-drug conjugates | Q28083123 | ||
Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses | Q28280944 | ||
Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21(Waf1/Cip1) as a novel mechanism of neuroprotection by glucocorticoids | Q28569805 | ||
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function | Q29615582 | ||
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling | Q29615601 | ||
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Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo | Q69839044 | ||
Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease | Q72157868 | ||
A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III) | Q77398255 | ||
Upscaling of hiPS Cell-Derived Neurons for High-Throughput Screening | Q89351015 | ||
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice | Q30486668 | ||
Short-term striatal gene expression responses to brain-derived neurotrophic factor are dependent on MEK and ERK activation | Q33434423 | ||
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. | Q33664194 | ||
The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes | Q34013346 | ||
Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells | Q34036456 | ||
Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery | Q34060172 | ||
The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors | Q34150847 | ||
Pharmacological characterization of six trkB antibodies reveals a novel class of functional agents for the study of the BDNF receptor | Q34588700 | ||
Activation of TrkB with TAM-163 results in opposite effects on body weight in rodents and non-human primates | Q34734974 | ||
Selecting agonists from single cells infected with combinatorial antibody libraries | Q34740000 | ||
A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease | Q35087700 | ||
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Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects | Q35856484 | ||
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy | Q36165553 | ||
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome. | Q36212795 | ||
FDA drug approval summary: panitumumab (Vectibix). | Q36830592 | ||
Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection | Q36959335 | ||
Up-regulation of brain-derived neurotrophic factor by application of fibroblast growth factor-2 to the cut optic nerve is important for long-term survival of retinal ganglion cells. | Q36984309 | ||
A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome | Q37008339 | ||
Brain-derived neurotrophic factor prevents dendritic retraction of adult mouse retinal ganglion cells. | Q37183432 | ||
A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease | Q37345118 | ||
Neurotrophin signalling: novel insights into mechanisms and pathophysiology | Q37629100 | ||
More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy. | Q37729120 | ||
Potential therapeutic uses of BDNF in neurological and psychiatric disorders | Q37848053 | ||
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Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons. | Q38807798 | ||
Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons | Q38810200 | ||
Activin induces cortical interneuron identity and differentiation in embryonic stem cell-derived telencephalic neural precursors | Q39347922 | ||
An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma | Q39720313 | ||
Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities. | Q40232259 | ||
Trophic support of motoneurons: physiological, pathophysiological, and therapeutic implications. | Q40801545 | ||
Gadd45b is a novel mediator of neuronal apoptosis in ischemic stroke | Q41978642 | ||
Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain. | Q42060253 | ||
Neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in Alzheimer's disease. | Q42471938 | ||
Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection | Q42497039 | ||
Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type A GABA receptor alpha 4 subunits in hippocampal neurons | Q42499572 | ||
Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function | Q43148661 | ||
The non-peptidyl fungal metabolite L-783,281 activates TRK neurotrophin receptors | Q43735224 | ||
TrkB agonists ameliorate obesity and associated metabolic conditions in mice | Q46212129 | ||
Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death. | Q47763741 | ||
Multiplex quantitative assays indicate a need for reevaluating reported small-molecule TrkB agonists. | Q47791149 | ||
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis | Q48686925 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International | Q24082749 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 30 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | E7023-E7032 | |
P577 | publication date | 2018-07-09 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library | |
P478 | volume | 115 |
Q94601574 | Brain-Derived Neurotrophic Factor and Its Potential Therapeutic Role in Stroke Comorbidities |
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