Phenotype of p53 wild-type epitope-specific T cells in the circulation of patients with head and neck cancer

scientific article published in Scientific Reports

Phenotype of p53 wild-type epitope-specific T cells in the circulation of patients with head and neck cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-018-29067-5
P932PMC publication ID6048165
P698PubMed publication ID30013227

P50authorAndreas E. AlbersQ56953041
Robert L FerrisQ38328358
P2093author name stringXu Qian
Andreas M Kaufmann
Thomas K Hoffmann
Albert B DeLeo
Daphne Mytilineos
P2860cites workFrequencies of tetramer+ T cells specific for the wild-type sequence p53(264-272) peptide in the circulation of patients with head and neck cancer.Q52012168
ALDH1-positive cancer stem-like cells are enriched in nodal metastases of oropharyngeal squamous cell carcinoma independent of HPV status.Q52884612
[Prophylactic and therapeutic vaccines against human papilloma virus].Q52903256
Alterations in the T-cell receptor variable beta gene-restricted profile of CD8+ T lymphocytes in the peripheral circulation of patients with squamous cell carcinoma of the head and neck.Q53625790
Immune responses to p53 in patients with cancer: enrichment in tetramer+ p53 peptide-specific T cells and regulatory T cells at tumor sitesQ56902548
The Ability of Variant Peptides to Reverse the Nonresponsiveness of T Lymphocytes to the Wild-Type Sequence p53264-272 EpitopeQ57209306
Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importanceQ74597422
Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinomaQ77670022
Functional subsets of memory T cells identified by CCR7 expressionQ28141547
The mutational landscape of head and neck squamous cell carcinomaQ29614654
Central memory and effector memory T cell subsets: function, generation, and maintenanceQ29615097
Phase I dendritic cell p53 peptide vaccine for head and neck cancerQ30577847
Signaling defects in T lymphocytes of patients with malignancyQ33740933
Induction docetaxel, cisplatin, and cetuximab followed by concurrent radiotherapy, cisplatin, and cetuximab and maintenance cetuximab in patients with locally advanced head and neck cancerQ34477841
CTLA-4⁺ Regulatory T Cells Increased in Cetuximab-Treated Head and Neck Cancer Patients Suppress NK Cell Cytotoxicity and Correlate with Poor PrognosisQ35674757
Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancerQ36616391
Lack of MHC class I surface expression on neoplastic cells and poor activation of the secretory pathway of cytotoxic cells in oral squamous cell carcinomasQ36640998
Spontaneous apoptosis of tumor-specific tetramer+ CD8+ T lymphocytes in the peripheral circulation of patients with head and neck cancerQ37040545
Biology and immunology of cancer stem(-like) cells in head and neck cancerQ38439697
Antitumor activity of human papillomavirus type 16 E7-specific T cells against virally infected squamous cell carcinoma of the head and neck.Q40344942
Tumor-infiltrating Tim-3+ T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk.Q40448724
Effect of human papillomavirus-16 infection on CD8+ T-cell recognition of a wild-type sequence p53264-272 peptide in patients with squamous cell carcinoma of the head and neck.Q40500501
Generation of T cells specific for the wild-type sequence p53(264-272) peptide in cancer patients: implications for immunoselection of epitope loss variantsQ40739857
The use of HLA A2.1/p53 peptide tetramers to visualize the impact of self tolerance on the TCR repertoireQ40908102
Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cellsQ40944863
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and NeckQ43164702
Prognostic significance of ALDH1A1-positive cancer stem cells in patients with locally advanced, metastasized head and neck squamous cell carcinomaQ45019691
PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer.Q47806987
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecthead and neck cancerQ1783924
head and neck carcinomaQ18554836
neck cancerQ18966654
P304page(s)10716
P577publication date2018-07-16
P1433published inScientific ReportsQ2261792
P1476titlePhenotype of p53 wild-type epitope-specific T cells in the circulation of patients with head and neck cancer
P478volume8

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Q90350381A Potent Tumor-Reactive p53-Specific Single-Chain TCR without On- or Off-Target Autoimmunity In Vivocites workP2860

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