Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma

scientific article published on 27 June 2011

Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1158/0008-5472.CAN-10-4179
P698PubMed publication ID21708957

P50authorIsabelle CremerQ28317113
Catherine Sautès-FridmanQ40020459
Wolf Hervé FridmanQ40876588
Sophia PlatonovaQ118383367
Lucile CrozetQ118383368
P2093author name stringMarco Alifano
Diane Damotte
Marie-Caroline Dieu-Nosjean
Pierre Validire
Vincent Vieillard
Julien Cherfils-Vicini
Jean-François Régnard
Pascale André
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
lung carcinomaQ18556110
P304page(s)5412-5422
P577publication date2011-06-27
P1433published inCancer ResearchQ326097
P1476titleProfound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma
P478volume71

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cites work (P2860)
Q35131244A think tank of TINK/TANKs: tumor-infiltrating/tumor-associated natural killer cells in tumor progression and angiogenesis
Q44717067Alterations of oncogenes expression in NK cells in patients with cancer
Q46186877Altered phenotype in peripheral blood and tumor-associated NK cells from colorectal cancer patients
Q55252861Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.
Q91971683An Historical Overview: The Discovery of How NK Cells Can Kill Enemies, Recruit Defense Troops, and More
Q60302404Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
Q90506533B cell and B cell-related pathways for novel cancer treatments
Q92299151Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells
Q34658702CD11b(-)CD27(-) NK cells are associated with the progression of lung carcinoma
Q89996479Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2
Q36130505Cellular and molecular immunology of lung cancer: therapeutic implications.
Q27329648Cetuximab Reconstitutes Pro-Inflammatory Cytokine Secretions and Tumor-Infiltrating Capabilities of sMICA-Inhibited NK Cells in HNSCC Tumor Spheroids
Q27012852Characteristics of tertiary lymphoid structures in primary cancers
Q35719855Characterization of the Microenvironment in Positive and Negative Sentinel Lymph Nodes from Melanoma Patients
Q92845938Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming
Q38855882Critical role of the NKG2D receptor for NK cell-mediated control and immune escape of B-cell lymphoma
Q38559350Critical roles of co-activation receptor DNAX accessory molecule-1 in natural killer cell immunity
Q30648415Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids
Q36821101Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC.
Q38207947Effect of tumor cells and tumor microenvironment on NK-cell function.
Q38819280Emerging insights into natural killer cells in human peripheral tissues.
Q90748125Endometrial Cancer Immune Escape Mechanisms: Let Us Learn From the Fetal-Maternal Interface
Q92601787Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation
Q38671184Exploiting natural killer group 2D receptors for CAR T-cell therapy.
Q88550353Expression of LLT1 and its receptor CD161 in lung cancer is associated with better clinical outcome
Q52725437Expression of NK Cell Surface Receptors in Breast Cancer Tissue as Predictors of Resistance to Antineoplastic Treatment.
Q28088304From mice to humans: developments in cancer immunoediting
Q60960579Genomic loss of HLA alleles may affect the clinical outcome in low-risk myelodysplastic syndrome patients
Q47680181High PD-L1 expression indicates poor prognosis of HIV-infected patients with non-small cell lung cancer
Q35987354Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer
Q92341987Host tissue determinants of tumour immunity
Q41474657How melanoma cells inactivate NK cells
Q38004630Human NK cell recognition of target cells in the prism of natural cytotoxicity receptors and their ligands.
Q38196803Human NK cells: from surface receptors to the therapy of leukemias and solid tumors
Q38569646Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias.
Q59136348Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
Q42279197Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC.
Q37191088IL-18-primed helper NK cells collaborate with dendritic cells to promote recruitment of effector CD8+ T cells to the tumor microenvironment
Q39259470IL-2- or IL-15-activated NK cells enhance Cetuximab-mediated activity against triple-negative breast cancer in xenografts and in breast cancer patients
Q61803780Immune Cell Composition in Human Non-small Cell Lung Cancer
Q56892179Immune Prophets of Lung Cancer: The Prognostic and Predictive Landscape of Cellular and Molecular Immune Markers
Q38007549Immune alterations and emerging immunotherapeutic approaches in lung cancer
Q53743967Immune-Mediated and Hypoxia-Regulated Programs: Accomplices in Resistance to Anti-angiogenic Therapies.
Q38840291Immunological Consequences of Epithelial-Mesenchymal Transition in Tumor Progression.
Q92768544Immunometabolism: A new target for improving cancer immunotherapy
Q26750617Immunotherapy for lung cancer: advances and prospects
Q30422102Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma
Q92783338Impact of Tumor and Immunological Heterogeneity on the Anti-Cancer Immune Response
Q64255314Innate Lymphoid Cells in Mucosal Immunity
Q40692653Liver-infiltrating CD11b(-)CD27(-) NK subsets account for NK-cell dysfunction in patients with hepatocellular carcinoma and are associated with tumor progression
Q36057423Loss-of-function alleles of P2RX7 and TLR4 fail to affect the response to chemotherapy in non-small cell lung cancer
Q38181691Lung cancer: potential targets for immunotherapy
Q36584068Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells
Q59793946Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients
Q64066131Mechanisms involved in IL-15 superagonist enhancement of anti-PD-L1 therapy
Q39348282Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor.
Q44837814Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions.
Q34541173NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome
Q90265781NK Cell Dysfunction and Checkpoint Immunotherapy
Q39431541NK Cell Exhaustion.
Q90229650NK Cell Hyporesponsiveness: More Is Not Always Better
Q90226003NK Cell Plasticity in Cancer
Q91638860NK Cells in the Human Lungs
Q26746478NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?
Q102057122NK cell infiltration is associated with improved overall survival in solid cancers: A systematic review and meta-analysis
Q56965731NK cells from pleural effusions are potent antitumor effector cells
Q36453421NK cells in healthy aging and age-associated diseases
Q41967990NK cells sense tumors, course of disease and treatments: Consequences for NK-based therapies
Q27014888NKG2D ligands as therapeutic targets
Q64102223NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment
Q37616478NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients
Q37558627NKp30 isoforms and NKp46 transcripts in metastatic melanoma patients: Unique NKp30 pattern in rare melanoma patients with favorable evolution
Q37688634NKp44 and NKp30 splice variant profiles in decidua and tumor tissues: a comparative viewpoint
Q43185293Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment.
Q26772347Natural Killer Cell Immunomodulation: Targeting Activating, Inhibitory, and Co-stimulatory Receptor Signaling for Cancer Immunotherapy
Q91782587Natural Killer Cells in the Lungs
Q38872473Natural Killers Are Made Not Born: How to Exploit NK Cells in Lung Malignancies.
Q35743162Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differentia
Q21131216Natural killer cell mediated antibody-dependent cellular cytotoxicity in tumor immunotherapy with therapeutic antibodies
Q57395724Natural killer cells and other innate lymphoid cells in cancer
Q48130583Natural killer cells and tumor metastasis
Q38352462Natural killer cells as helper cells in dendritic cell cancer vaccines
Q36486204Natural killer cells in non-hematopoietic malignancies
Q33869781New insights into the role of EMT in tumor immune escape.
Q26829161New modalities of cancer treatment for NSCLC: focus on immunotherapy
Q38953461Novel immunotherapy in the treatment of advanced non-small cell lung cancer
Q52716894Oncogenes in immune cells as potential therapeutic targets.
Q28389236Orchestration of angiogenesis by immune cells
Q38173706Organ-specific phenotypic and functional features of NK cells in humans
Q41333332Overexpression of CD85j in TNBC patients inhibits Cetuximab-mediated NK-cell ADCC but can be restored with CD85j functional blockade
Q42209070Patient's Natural Killer Cells in the Era of Targeted Therapies: Role for Tumor Killers.
Q37323344Phenotypic and Functional Dysregulated Blood NK Cells in Colorectal Cancer Patients Can Be Activated by Cetuximab Plus IL-2 or IL-15.
Q35034899Phenotypic and functional characteristics of blood natural killer cells from melanoma patients at different clinical stages
Q35677351Present and Future of Allogeneic Natural Killer Cell Therapy
Q97883497Prognostic Significance of Tumor-Infiltrating Natural Killer Cells in Solid Tumors: A Systematic Review and Meta-Analysis
Q38394496Prognostic and predictive significance of immune cells infiltrating cutaneous melanoma
Q37616484Prognostic impact of the expression of NCR1 and NCR3 NK cell receptors and PD-L1 on advanced non-small cell lung cancer
Q55440274Prognostic significance of immune cells in non-small cell lung cancer: meta-analysis.
Q33798257Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance
Q26752551Regulation of Natural Killer Cell Function by STAT3
Q33714165Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade
Q43180026Reversal of natural killer cell exhaustion by TIM-3 blockade
Q48240289Reversal of tumor acidosis by systemic buffering reactivates NK cells to express IFN-γ and induces NK cell-dependent lymphoma control without other immunotherapies.
Q39210022Role of Distinct Natural Killer Cell Subsets in Anticancer Response
Q38575116Role of NK cells in immunotherapy and virotherapy of solid tumors
Q93172097Role of cytokines in combinatorial immunotherapeutics of non-small cell lung cancer through systems perspective
Q52608280Role of natural killer cells in lung cancer.
Q49630355Splice variants of human natural cytotoxicity receptors: novel innate immune checkpoints
Q37659765TGF-β-inducible microRNA-183 silences tumor-associated natural killer cells.
Q38200088TLR/NCR/KIR: Which One to Use and When?
Q64272018TNF-α-induced Tim-3 expression marks the dysfunction of infiltrating natural killer cells in human esophageal cancer
Q58621104TNFR2/BIRC3-TRAF1 signaling pathway as a novel NK cell immune checkpoint in cancer
Q90693846Targeted Therapies: Friends or Foes for Patient's NK Cell-Mediated Tumor Immune-Surveillance?
Q56889003Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells
Q37995950Targeting natural killer cells and natural killer T cells in cancer
Q92615075Targeting natural killer cells in solid tumors
Q39281940Targeting the tumor microenvironment to improve natural killer cell-based immunotherapies: On being in the right place at the right time, with resilience.
Q35110486Tertiary Lymphoid Structure-Associated B Cells are Key Players in Anti-Tumor Immunity
Q41049892The breast tumor microenvironment alters the phenotype and function of natural killer cells
Q37413162The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity.
Q29620667The immune contexture in human tumours: impact on clinical outcome
Q37028764The immune microenvironment of human tumors: general significance and clinical impact
Q34315871The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells
Q38264982The non-small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome
Q36629398The proangiogenic phenotype of natural killer cells in patients with non-small cell lung cancer
Q35549712The role of natural killer cells in pulmonary immunosurveillance
Q26744076The role of pembrolizumab in the treatment of advanced non-small cell lung cancer
Q38039112The split nature of tumor-infiltrating leukocytes: Implications for cancer surveillance and immunotherapy
Q38101567The tumor microenvironment: a pitch for multiple players.
Q57300016Tissue-Resident Lymphocytes Across Innate and Adaptive Lineages
Q38089253Tissue-specific effector functions of innate lymphoid cells.
Q91706130Transcriptional Characterization Of The Tumor Immune Microenvironment And Its Prognostic Value For Locally Advanced Lung Adenocarcinoma In A Chinese Population
Q55107050Tumor immunotherapy: New aspects of natural killer cells.
Q42398706Tumor lymphocytic infiltration in non-small cell lung cancer: the ultimate prognostic marker?
Q36038484Tumor microenvironment in NSCLC suppresses NK cells function
Q92990742Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer
Q26766468Tumour progression and metastasis
Q90176787Unleashing Natural Killer Cells in the Tumor Microenvironment-The Next Generation of Immunotherapy?
Q41807120When breast cancer cells start to fend the educational process of NK cells off.
Q34364808mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.

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