scholarly article | Q13442814 |
P50 | author | Robert J Shmookler Reis | Q92076665 |
P2093 | author name string | Srinivas Ayyadevara | |
Meenakshisundaram Balasubramaniam | |||
P2860 | cites work | Human proteins with target sites of multiple post-translational modification types are more prone to be involved in disease. | Q53142477 |
Modeling polyglutamine pathogenesis in C. elegans | Q79259216 | ||
Protein Homeostasis in Models of Aging and Age-Related Conformational Disease | Q36109387 | ||
Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. | Q37235572 | ||
Protein aggregates in Huntington's disease. | Q37540988 | ||
Inefficient degradation of truncated polyglutamine proteins by the proteasome | Q37592772 | ||
Autophagy basics | Q37822872 | ||
Overexpression of Rad23 confers resistance to methylmercury in saccharomyces cerevisiae via inhibition of the degradation of ubiquitinated proteins | Q38324000 | ||
Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity. | Q39665589 | ||
Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates. | Q39878605 | ||
Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A. | Q40488188 | ||
The phosphatase calcineurin regulates pathological TDP-43 phosphorylation. | Q41628256 | ||
Solution structure of the ubiquitin-associated domain of human BMSC-UbP and its complex with ubiquitin | Q41768339 | ||
SERF protein is a direct modifier of amyloid fiber assembly. | Q41810757 | ||
Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain | Q42139176 | ||
Accelerating and focusing protein-protein docking correlations using multi-dimensional rotational FFT generating functions | Q43063724 | ||
Behavioral phenotyping of a transgenic Caenorhabditis elegans expressing neuronal amyloid-beta | Q43181445 | ||
Specificity of the interaction between ubiquitin-associated domains and ubiquitin | Q46197886 | ||
Conformational disease | Q46332791 | ||
Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans | Q48632135 | ||
Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone | Q24307892 | ||
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration | Q24337490 | ||
A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways | Q24594082 | ||
I-TASSER: a unified platform for automated protein structure and function prediction | Q24605680 | ||
Widespread protein aggregation as an inherent part of aging in C. elegans | Q27323997 | ||
Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions | Q27639223 | ||
Structural Assembly of Multidomain Proteins and Protein Complexes Guided by the Overall Rotational Diffusion Tensor | Q27645280 | ||
Crystal structure of cyclic Lys48-linked tetraubiquitin | Q27664117 | ||
Structural Analysis of the Conserved Ubiquitin-binding Motifs (UBMs) of the Translesion Polymerase iota in Complex with Ubiquitin | Q27664947 | ||
VMD: visual molecular dynamics | Q27860554 | ||
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling | Q27860614 | ||
Rad23 interaction with the proteasome is regulated by phosphorylation of its ubiquitin-like (UbL) domain | Q27934619 | ||
Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system | Q27935666 | ||
Autophagy in neurodegenerative diseases: from mechanism to therapeutic approach | Q28084605 | ||
Small changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and disease | Q28396109 | ||
Rad23 links DNA repair to the ubiquitin/proteasome pathway | Q29614361 | ||
The role of the Atg1/ULK1 complex in autophagy regulation | Q29614497 | ||
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit | Q29615867 | ||
Ubiquitin-binding domains | Q29616461 | ||
Genome-wide RNAi screening in Caenorhabditis elegans | Q29617900 | ||
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans | Q29619760 | ||
MSUT2 is a determinant of susceptibility to tau neurotoxicity | Q30499781 | ||
Atomistic simulations of the effects of polyglutamine chain length and solvent quality on conformational equilibria and spontaneous homodimerization | Q33761386 | ||
PONDR-FIT: a meta-predictor of intrinsically disordered amino acids | Q33902242 | ||
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution | Q34225700 | ||
Rad23 promotes the targeting of proteolytic substrates to the proteasome | Q34283029 | ||
Protein aggregation: folding aggregates, inclusion bodies and amyloid | Q34460420 | ||
The biology of proteostasis in aging and disease | Q34467650 | ||
Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes | Q35080559 | ||
Misfolded proteins in Alzheimer's disease and type II diabetes. | Q35535599 | ||
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. | Q35968298 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Caenorhabditis elegans | Q91703 |
P304 | page(s) | 14891 | |
P577 | publication date | 2018-10-05 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2 | |
P478 | volume | 8 |
Q92535155 | A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease |
Q90591360 | Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases |
Q101038683 | Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs |