Molecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges

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Molecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges is …
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scholarly articleQ13442814

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P356DOI10.1186/S12917-018-1613-Y
P932PMC publication ID6169072
P698PubMed publication ID30285759

P50authorHua LiQ91790628
P2093author name stringTing Li
Lei Wang
Fumiao Zhang
Guiwen Yang
Xinyi Guo
Wujun Wen
Xinze Chen
Yonghuan Zhang
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In vivo evoked specific cell mediated cytotoxicity in carp (Cyprinus carpio L.) uses mainly a perforin/granzyme-like pathwayQ40417277
Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.Q40485512
CD8-mediated protection against Ebola virus infection is perforin dependentQ40512594
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A Leukocyte Immune-Type Receptor Subset Is a Marker of Antiviral Cytotoxic Cells in Channel Catfish, Ictalurus punctatus.Q40800053
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Expression profile of carp IFN correlate with the up-regulation of interferon regulatory factor-1 (IRF-1) in vivo and in vitro: the pivotal molecules in antiviral defenseQ40844541
Proinflammatory Caspase A Activation and an Antiviral State Are Induced by a Zebrafish Perforin after Possible Cellular and Functional Diversification from a Myeloid Ancestor.Q41152470
Lymphocyte-mediated cytolysis and diseaseQ41224272
Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infectionQ41992035
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Molecular characterization of hepcidin gene in common carp (Cyprinus carpio L.) and its expression pattern responding to bacterial challengeQ44448156
Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8+ T cellsQ45391522
CD8+ T cells clear influenza virus by perforin or Fas-dependent processes.Q45756742
Carp (Cyprinus carpio L.) innate immune factors are present before hatching.Q46708725
Direct recognition of LPS by human but not murine CD8+ T cells via TLR4 complexQ47911048
Ontogenetic profile of innate immune related genes and their tissue-specific expression in brown trout, Salmo trutta (Linnaeus, 1758).Q48523088
Non-mammalian Toll-like receptor 18 (Tlr18) recognizes bacterial pathogens in common carp (Cyprinus carpio L.): Indications for a role of participation in the NF-κB signaling pathway.Q50125850
Administration to mouse of endotoxin from gram-negative bacteria leads to activation and apoptosis of T lymphocytes.Q50131711
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
CD8+ T Cells Require Perforin To Clear West Nile Virus from Infected NeuronsQ27472780
Differences in Hepatitis C Virus (HCV)-Specific CD8 T-Cell Phenotype during Pegylated Alpha Interferon and Ribavirin Treatment Are Related to Response to Antiviral Therapy in Patients Chronically Infected with HCVQ27486579
A common fold mediates vertebrate defense and bacterial attackQ27647495
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The structural basis for membrane binding and pore formation by lymphocyte perforinQ27665482
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Homology of perforin to the ninth component of complement (C9).Q34171313
Structure and function of human perforinQ34178477
Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within EuteleostomiQ34253572
Early immune responses in rainbow trout liver upon viral hemorrhagic septicemia virus (VHSV) infectionQ34388643
Molecular cloning and chromosomal assignment of a human perforin (PFP) geneQ34474013
A linkage map of transcribed single nucleotide polymorphisms in rohu (Labeo rohita) and QTL associated with resistance to Aeromonas hydrophila.Q34485441
The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into naïve recipient miceQ34774050
Expression of Perforin Gene for Early Development of Nephrons in Olive Flounder (Paralichthys olivaceus).Q35246780
Characterization of common carp (Cyprinus carpio L.) interferon regulatory factor 5 (IRF5) and its expression in response to viral and bacterial challengesQ36062800
Tyrosine kinase Btk is required for NK cell activationQ36078834
The structure of the mouse lymphocyte pore-forming protein perforinQ36189695
Diesel exhaust particles modify natural killer cell function and cytokine releaseQ36798156
Isopentenyl pyrophosphate-activated CD56+ {gamma}{delta} T lymphocytes display potent antitumor activity toward human squamous cell carcinomaQ37038276
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Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granulesQ37540753
Cytotoxic T cells in teleost fishQ37870403
Molecular characterization and expression pattern of X box-binding protein-1 (XBP1) in common carp (Cyprinus carpio L.): Indications for a role of XBP1 in antibacterial and antiviral immunityQ38701687
NK cells kill mycobacteria directly by releasing perforin and granulysin.Q38964482
Endocytosis by target cells: an essential means for perforin- and granzyme-mediated killingQ39021577
Viral hemorrhagic septicaemia virus (VHSV) up-regulates the cytotoxic activity and the perforin/granzyme pathway in the rainbow trout RTS11 cell lineQ39530473
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcommon carpQ81110
P304page(s)299
P577publication date2018-10-03
P1433published inBMC Veterinary ResearchQ15751340
P1476titleMolecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges
P478volume14

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Q92815606Nanomaterials-based Electrochemical Immunosensorscites workP2860

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