| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.VIROL.2018.08.009 |
| P698 | PubMed publication ID | 30142572 |
| P50 | author | Terrence M Tumpey | Q87490350 |
| Taronna R Maines | Q88489175 | ||
| Jessica A Belser | Q88489180 | ||
| P2093 | author name string | Terrence M Tumpey | |
| Taronna R Maines | |||
| Jessica A Belser | |||
| P2860 | cites work | A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence | Q21089626 |
| Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals | Q22255464 | ||
| Updating the Accounts: Global Mortality of the 1918-1920 "Spanish" Influenza Pandemic | Q22306097 | ||
| Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus. | Q24536333 | ||
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| The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease | Q27564108 | ||
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| Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin | Q27667831 | ||
| Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin | Q27861017 | ||
| A novel influenza A virus mitochondrial protein that induces cell death. | Q27863709 | ||
| Update on avian influenza A (H5N1) virus infection in humans | Q28264923 | ||
| Characterization of the 1918 influenza virus polymerase genes | Q28275749 | ||
| Characterization of the reconstructed 1918 Spanish influenza pandemic virus | Q28275911 | ||
| Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus | Q28283850 | ||
| A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission | Q28286390 | ||
| Transmissibility of 1918 pandemic influenza | Q28298620 | ||
| H5N1 Virus Attachment to Lower Respiratory Tract | Q28303460 | ||
| Initial genetic characterization of the 1918 "Spanish" influenza virus | Q28305563 | ||
| Pathogenicity and transmissibility of North American triple reassortant swine influenza A viruses in ferrets | Q28386553 | ||
| Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans | Q29619059 | ||
| In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses | Q29619174 | ||
| Seasonal trivalent inactivated influenza vaccine protects against 1918 Spanish influenza virus infection in ferrets | Q30416288 | ||
| Interspecies transmission of influenza viruses | Q30416948 | ||
| Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice | Q29619193 | ||
| Avian flu: influenza virus receptors in the human airway | Q29619374 | ||
| Airborne transmission of influenza A/H5N1 virus between ferrets | Q29619970 | ||
| Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets | Q29619972 | ||
| European swine virus as a possible source for the next influenza pandemic? | Q30011195 | ||
| Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck | Q30204229 | ||
| Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands | Q30233303 | ||
| Are we ready for pandemic influenza? | Q30233355 | ||
| Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza | Q30331304 | ||
| Characterization of the 1918 "Spanish" influenza virus matrix gene segment | Q30332027 | ||
| The origin of the 1918 pandemic influenza virus: a continuing enigma. | Q30333284 | ||
| Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus. | Q30339011 | ||
| Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. | Q30343761 | ||
| A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. | Q30351248 | ||
| Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice | Q30351800 | ||
| Characterization of H7N9 influenza A viruses isolated from humans. | Q30352001 | ||
| Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. | Q30352169 | ||
| Avian influenza and the brain--comments on the occasion of resurrection of the Spanish flu virus. | Q30352860 | ||
| Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses | Q30354832 | ||
| Influenza A virus infections in swine: pathogenesis and diagnosis. | Q30357141 | ||
| Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus. | Q30361887 | ||
| Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential. | Q30363524 | ||
| H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice | Q30364306 | ||
| Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia | Q30365855 | ||
| Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling. | Q30366877 | ||
| Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus | Q30367863 | ||
| Origin of the 1918 Spanish influenza virus: a comparative genomic analysis. | Q30368332 | ||
| Influenza A virus transmission bottlenecks are defined by infection route and recipient host. | Q30369231 | ||
| Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses. | Q30369896 | ||
| H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. | Q30371122 | ||
| Advances in the development of influenza virus vaccines. | Q30372164 | ||
| The use of nonhuman primates in research on seasonal, pandemic and avian influenza, 1893-2014. | Q30372479 | ||
| Viral RNA polymerase complex promotes optimal growth of 1918 virus in the lower respiratory tract of ferrets. | Q30374134 | ||
| Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: antiviral potential of exogenous alpha interferon to reduce virus shedding | Q30374356 | ||
| Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air. | Q30374897 | ||
| Origin of the Pandemic 1957 H2 Influenza A Virus and the Persistence of Its Possible Progenitors in the Avian Reservoir | Q30417949 | ||
| Virulence and transmissibility of H1N2 influenza virus in ferrets imply the continuing threat of triple-reassortant swine viruses | Q30421737 | ||
| Molecular evolution of influenza viruses | Q30425316 | ||
| Emerging infections: pandemic influenza | Q30425597 | ||
| Inducible nitric oxide contributes to viral pathogenesis following highly pathogenic influenza virus infection in mice | Q30427380 | ||
| H5N1 pathogenesis studies in mammalian models | Q30427806 | ||
| Molecular basis for the generation in pigs of influenza A viruses with pandemic potential | Q30431215 | ||
| N-linked glycosylation of the hemagglutinin protein influences virulence and antigenicity of the 1918 pandemic and seasonal H1N1 influenza A viruses | Q30431513 | ||
| Triple-reassortant swine influenza A (H1) in humans in the United States, 2005-2009. | Q33384415 | ||
| Evolutionary dynamics of N-glycosylation sites of influenza virus hemagglutinin. | Q33520040 | ||
| The emergence of novel swine influenza viruses in North America | Q33959377 | ||
| Decoding the distribution of glycan receptors for human-adapted influenza A viruses in ferret respiratory tract | Q34167968 | ||
| The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets | Q35826884 | ||
| Transmission of influenza A viruses between pigs and people, Iowa, 2002–2004 | Q36252645 | ||
| An overlapping protein-coding region in influenza A virus segment 3 modulates the host response | Q36554219 | ||
| A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. | Q36685680 | ||
| Limited airborne transmission of H7N9 influenza A virus between ferrets | Q37284438 | ||
| Comparative pathology of select agent influenza a virus infections. | Q37777544 | ||
| Influenza A(H1N1)pdm09-related pneumonia and other complications | Q38057069 | ||
| Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice | Q39127763 | ||
| PB1-F2 modulates early host responses but does not affect the pathogenesis of H1N1 seasonal influenza virus | Q39399599 | ||
| NS1-mediated delay of type I interferon induction contributes to influenza A virulence in ferrets | Q39575169 | ||
| Population Diversity and Collective Interactions during Influenza Virus Infection | Q40064406 | ||
| SWINE INFLUENZA : I. EXPERIMENTAL TRANSMISSION AND PATHOLOGY. | Q41764089 | ||
| THE INFECTION OF FERRETS WITH SWINE INFLUENZA VIRUS. | Q41892724 | ||
| Clusters of Human Infections With Avian Influenza A(H7N9) Virus in China, March 2013 to June 2015. | Q41925026 | ||
| Human Infection with a Novel Avian Influenza A(H5N6) Virus. | Q43169145 | ||
| Spread of a novel influenza A (H1N1) virus via global airline transportation | Q45383197 | ||
| Ferrets as a transmission model for influenza: sequence changes in HA1 of type A (H3N2) virus | Q45736199 | ||
| 1918 H1N1 influenza virus replicates and induces pro-inflammatory cytokine responses in extra-respiratory tissues of ferrets | Q47554305 | ||
| Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States | Q49916700 | ||
| The evolution of seasonal influenza viruses | Q50453718 | ||
| A Virus Obtained from Influenza Patients | Q54077976 | ||
| Antigenically Diverse Swine Origin H1N1 Variant Influenza Viruses Exhibit Differential Ferret Pathogenesis and Transmission Phenotypes. | Q54255837 | ||
| Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments. | Q55399537 | ||
| Genetic analysis and antigenic characterization of swine origin influenza viruses isolated from humans in the United States, 1990-2010 | Q64127058 | ||
| Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets | Q64379999 | ||
| Experimental infection of pigs with the human 1918 pandemic influenza virus | Q30374993 | ||
| Resurrected pandemic influenza viruses. | Q30376358 | ||
| Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. | Q30378627 | ||
| Mapping influenza transmission in the ferret model to transmission in humans. | Q30378661 | ||
| Use of animal models to understand the pandemic potential of highly pathogenic avian influenza viruses. | Q30379985 | ||
| The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways | Q30380125 | ||
| An early 'classical' swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice. | Q30380435 | ||
| Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. | Q30380575 | ||
| The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice | Q30382370 | ||
| Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus | Q30384346 | ||
| Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism. | Q30384349 | ||
| Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission. | Q30385332 | ||
| PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models | Q30385984 | ||
| Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus. | Q30386800 | ||
| Epidemiological and virological differences in human clustered and sporadic infections with avian influenza A H7N9. | Q30388601 | ||
| The virulence of pandemic influenza A (H1N1) 2009: an epidemiological perspective on the case-fatality ratio | Q30390020 | ||
| Macaque proteome response to highly pathogenic avian influenza and 1918 reassortant influenza virus infections | Q30393667 | ||
| Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding | Q30393671 | ||
| Pathogenesis and transmission of triple-reassortant swine H1N1 influenza viruses isolated before the 2009 H1N1 pandemic | Q30396905 | ||
| Pandemic influenza 1918 H1N1 and 1968 H3N2 DNA vaccines induce cross-reactive immunity in ferrets against infection with viruses drifted for decades | Q30397107 | ||
| Influenza A virus transmission: contributing factors and clinical implications | Q30397203 | ||
| 2009 Pandemic influenza A (H1N1) deaths among children--United States, 2009-2010. | Q30400035 | ||
| Estimating the burden of 2009 pandemic influenza A (H1N1) in the United States (April 2009-April 2010). | Q30400038 | ||
| Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics | Q30400455 | ||
| A single base-pair change in 2009 H1N1 hemagglutinin increases human receptor affinity and leads to efficient airborne viral transmission in ferrets | Q30400777 | ||
| Novel influenza A viruses and pandemic threats. | Q30402808 | ||
| The ferret as a model organism to study influenza A virus infection | Q30405589 | ||
| Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets | Q30405793 | ||
| Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus | Q30407702 | ||
| Elicitation of anti-1918 influenza virus immunity early in life prevents morbidity and lower levels of lung infection by 2009 pandemic H1N1 influenza virus in aged mice | Q30410129 | ||
| Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives | Q30410899 | ||
| Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets | Q30413373 | ||
| Restored PB1-F2 in the 2009 pandemic H1N1 influenza virus has minimal effects in swine | Q30413680 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pandemic | Q12184 |
| P304 | page(s) | 45-55 | |
| P577 | publication date | 2018-08-22 | |
| P1433 | published in | Virology | Q7934867 |
| P1476 | title | Importance of 1918 virus reconstruction to current assessments of pandemic risk | |
| P478 | volume | 524 |
| Q89455930 | Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication | cites work | P2860 |
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