Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation

scientific article published on 06 February 2013

Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EJI.201242799
P698PubMed publication ID23303646

P50authorSharon R. LewinQ37618308
Jose A. VilladangosQ38360717
Justine D. MinternQ39631810
Irina CaminschiQ41610434
Elodie SeguraQ56433247
Gabriela KhouryQ63682046
Paul Urquhart CameronQ67957474
P2093author name stringJessica M Moffat
P2860cites workRegulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interactionQ24309134
BST-2/tetherin: a new component of the innate immune response to enveloped virusesQ24630382
Structural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus ReleaseQ27665937
Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursorsQ28585599
Tetherin inhibits retrovirus release and is antagonized by HIV-1 VpuQ29547836
Differential antigen processing by dendritic cell subsets in vivoQ29615177
Mature dendritic cells use endocytic receptors to capture and present antigensQ30493720
Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cellsQ33862227
CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.Q33928441
Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti–human DEC205 monoclonal antibodyQ34310888
The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen captureQ34771172
In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humansQ35170879
Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivoQ35518677
Preferential infection of dendritic cells during human immunodeficiency virus type 1 infection of blood leukocytes.Q35784640
Virus-activated interferon regulatory factor 7 upregulates expression of the interferon-regulated BST2 gene independently of interferon signalingQ35826825
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancementQ36941087
HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phaseQ37262510
Antigen-presentation properties of plasmacytoid dendritic cellsQ37272231
Mutz-3-derived Langerhans cells are a model to study HIV-1 transmission and potential inhibitorsQ39757211
Interferon-alpha enhances CD317 expression and the antitumor activity of anti-CD317 monoclonal antibody in renal cell carcinoma xenograft modelsQ39912541
Induction of HM1.24 peptide-specific cytotoxic T lymphocytes by using peripheral-blood stem-cell harvests in patients with multiple myelomaQ40394699
Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytesQ41578289
Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infectionQ42091648
Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cellsQ42767669
Testing recombinant adeno-associated virus-gene loading of dendritic cells for generating potent cytotoxic T lymphocytes against a prototype self-antigen, multiple myeloma HM1.24.Q43620870
Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells.Q44664018
Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunityQ45264704
Enhancing immune responses by targeting antigen to DC.Q46104542
CCR7 ligands CCL19 and CCL21 increase permissiveness of resting memory CD4+ T cells to HIV-1 infection: a novel model of HIV-1 latency.Q51971372
The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody ResponsesQ57133306
Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cellsQ57134111
Characterization of the ovalbumin-specific TCR transgenic line OT-I: MHC elements for positive and negative selectionQ57227959
Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elementsQ57228054
Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in the Naive Mouse, but a Promiscuous Cell Surface Antigen following IFN StimulationQ57275870
Facilitated antigen uptake and timed exposure to TLR ligands dictate the antigen-presenting potential of plasmacytoid DCsQ57920497
Dermal dendritic cells associated with T lymphocytes in normal human skin display an activated phenotypeQ77519513
HIV induces maturation of monocyte-derived dendritic cells and Langerhans cellsQ79326773
Antigen targeting to plasmacytoid dendritic cells via Siglec-H inhibits Th cell-dependent autoimmunityQ82486810
Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunityQ84069177
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectbone marrowQ546523
P304page(s)595-605
P577publication date2013-02-06
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleTargeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation
P478volume43

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cites work (P2860)
Q60956640Adjuvants Enhancing Cross-Presentation by Dendritic Cells: The Key to More Effective Vaccines?
Q56895711BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection
Q37524465Controlling immune responses by targeting antigens to dendritic cell subsets and B cells
Q42696952Dendritic cell-targeted vaccines--hope or hype?
Q35852742Differential use of autophagy by primary dendritic cells specialized in cross-presentation
Q35840924Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection
Q24297949Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1
Q26746162Targeting dendritic cells: a promising strategy to improve vaccine effectiveness
Q38235001Targeting human dendritic cells in situ to improve vaccines.
Q91999288The STING activator c-di-AMP exerts superior adjuvant properties than the formulation poly(I:C)/CpG after subcutaneous vaccination with soluble protein antigen or DEC-205-mediated antigen targeting to dendritic cells
Q33840201The novel immunotoxin HM1.24-ETA' induces apoptosis in multiple myeloma cells.

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