Mechanisms, biomarkers and targets for adult-onset Still's disease

scientific article published on 01 October 2018

Mechanisms, biomarkers and targets for adult-onset Still's disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41584-018-0081-X
P932PMC publication ID7097309
P698PubMed publication ID30218025

P50authorStéphane MitrovicQ64590625
P2093author name stringBruno Fautrel
Eugen Feist
P2860cites workA proposed classification of the immunological diseasesQ21144701
A frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
Still's disease in the adultQ24514809
Clinical characteristics and treatment outcomes of autoimmune-associated hemophagocytic syndrome in adultsQ26852503
Adult-onset Still's diseaseQ26852631
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
C13orf31 (FAMIN) is a central regulator of immunometabolic functionQ28115290
Adult-onset Still's disease with disseminated intravascular coagulation and multiple organ dysfunctions dramatically treated with cyclosporine AQ28167268
Ferritin in autoimmune diseasesQ28237318
Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndromeQ28239135
Primer: inflammasomes and interleukin 1beta in inflammatory disordersQ28263370
Adult-onset Still's disease: Advances in the treatment.Q30240644
Pro-resolving lipid mediators are leads for resolution physiologyQ30829097
Von Willebrand factor-cleaving protease (ADAMTS13) in thrombocytopenic disorders: a severely deficient activity is specific for thrombotic thrombocytopenic purpuraQ33343048
Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura.Q33359709
Deficient activity of von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura in the setting of adult-onset Still's diseaseQ33371300
Thrombotic thrombocytopenic purpura and adult onset Still's diseaseQ33383879
Thrombotic microangiopathy and purtscher-like retinopathy associated with adult-onset Still's disease: a role for glomerular vascular endothelial growth factor?Q33386885
A case of adult-onset Still's disease complicated by thrombotic thrombocytopenic purpura with retinal microangiopathy and rapidly fatal cerebral edemaQ33401390
Reactive macrophage activation syndrome possibly triggered by canakinumab in a patient with adult-onset Still's diseaseQ33408265
Life-threatening complications of adult-onset Still's diseaseQ33412732
Adult-onset still disease: manifestations, treatment, outcome, and prognostic factors in 57 patientsQ33414045
An Unusual Case of Adult-Onset Still's Disease with Hemophagocytic Syndrome, Necrotic Leukoencephalopathy and Disseminated Intravascular Coagulation.Q33414465
Epidemiology of adult Still's disease: estimate of the incidence by a retrospective study in west FranceQ33578168
Soluble CD163.Q34029313
Secondary renal amyloidosis in adult onset Still's disease: case report and review of the literatureQ34036420
Pathogenesis of adult-onset Still's disease: new insights from the juvenile counterpart.Q34042413
Association between adult-onset Still's disease and interleukin-18 gene polymorphismsQ34158398
Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questionsQ34269827
Proinflammatory S100 proteins in arthritis and autoimmune diseaseQ34375738
Tocilizumab-Induced Acute Liver Injury in Adult Onset Still's DiseaseQ34399037
Preliminary criteria for classification of adult Still's diseaseQ34405573
Interleukin 1 inhibition with anakinra in adult-onset Still disease: a meta-analysis of its efficacy and safetyQ34610098
Adult-onset Still's disease: can recent advances in our understanding of its pathogenesis lead to targeted therapy?Q34632947
The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndromeQ34966670
ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American CoQ34971421
Adult-onset Still's disease with disseminated intravascular coagulation and hemophagocytic syndrome: a case reportQ35017649
Adult-onset Still's disease.Q35227924
Percentage of glycosylated serum ferritin remains low throughout the course of adult onset Still's diseaseQ35549311
Synovial tissue interleukin-18 expression and the response to treatment in patients with inflammatory arthritisQ35553556
Tumour necrosis factor alpha blocking agents in refractory adult Still's disease: an observational study of 20 casesQ35555229
Successful treatment of a small cohort of patients with adult onset of Still's disease with infliximab: first experiencesQ35579173
The potential role of advanced glycation end products (AGEs) and soluble receptors for AGEs (sRAGE) in the pathogenesis of adult-onset still's diseaseQ35621852
Association of CXCL10 and CXCL13 levels with disease activity and cutaneous manifestation in active adult-onset Still's diseaseQ36073815
Efficacy of Anakinra in Refractory Adult-Onset Still's Disease: Multicenter Study of 41 Patients and Literature Review.Q36195807
Pulmonary Arterial Hypertension in Adult-Onset Still's Disease: Rapid Response to Anakinra.Q36220786
Gene-expression analysis of adult-onset Still's disease and systemic juvenile idiopathic arthritis is consistent with a continuum of a single disease entityQ36304070
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritisQ36435134
Ten years of clinical experience with adult onset Still's disease: is the outcome improving?Q36645748
Anakinra in patients with treatment-resistant adult-onset Still's disease: four case reports with serial cytokine measurements and a review of the literature.Q36855193
Pulmonary arterial hypertension in adult onset Still's disease: a case report of a severe complicationQ36886823
The NLR network and the immunological disease continuum of adaptive and innate immune-mediated inflammation against selfQ36931672
Pulmonary arterial hypertension secondary to adult-onset Still's disease: Response to cyclosporine and sildenafil over 15 years of follow-upQ37053491
S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown originQ37187378
TLR4 Endogenous Ligand S100A8/A9 Levels in Adult-Onset Still's Disease and Their Association with Disease Activity and Clinical ManifestationsQ37210206
Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cellsQ37240288
Adult-onset Still diseaseQ37333091
Systemic JIA: new developments in the understanding of the pathophysiology and therapyQ37620829
Adult Still's disease: manifestations, disease course, and outcome in 62 patientsQ37670649
Treatment of refractory adult-onset Still's disease with tocilizumab: report of two cases and review of the literatureQ37829362
Pro-resolution immunological networks: binding immunoglobulin protein and other resolution-associated molecular patterns.Q37970671
The use of Canakinumab, a novel IL-1β long-acting inhibitor, in refractory adult-onset Still's diseaseQ38003501
Ferritin in adult-onset still's disease: just a useful innocent bystander?Q38005702
Inheritance of autoinflammatory diseases: shifting paradigms and nomenclatureQ38093826
How should we approach classification of autoinflammatory diseases?Q38120387
A novel therapeutic approach in pulmonary arterial hypertension as a complication of adult-onset Still's disease: targeting IL-6.Q38192143
Immune dysregulation and endothelial dysfunction in pulmonary arterial hypertension: a complex interplayQ38198974
Adult onset Still's disease (AOSD) in the era of biologic therapies: dichotomous view for cytokine and clinical expressionsQ38245659
Validation of the Fautrel classification criteria for adult-onset Still's diseaseQ38651057
Adult onset Still's disease-The evidence that anti-interleukin-1 treatment is effective and well-tolerated (a comprehensive literature review).Q38652868
Coexistence of adult onset Still's disease and polymyositis with rhabdomyolysis successfully treated with methotrexate and corticosteroidsQ38669046
Response to Interleukin-1 Inhibitors in 140 Italian Patients with Adult-Onset Still's Disease: A Multicentre Retrospective Observational StudyQ38703626
An atypical presentation of adult-onset Still's disease complicated by pulmonary hypertension and macrophage activation syndrome treated with immunosuppression: a case-based review of the literatureQ38830731
Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and releaseQ38832683
The burgeoning field of innate immune-mediated disease and autoinflammationQ38967233
Lessons from characterization and treatment of the autoinflammatory syndromesQ39025839
Successful treatment of refractory adult onset Still's disease with rituximabQ39095921
Calcinosis cutis and intestinal pseudoobstruction in a patient with adult onset Still's disease associated with recurrent relapses of disordered coagulopathy.Q39513073
Adult Still's disease: review of 228 cases from the literatureQ39694157
Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 casesQ39782978
New Markers for Adult-Onset Still's DiseaseQ40056037
Macrophage Activation Syndrome Associated with Adult-Onset Still's Disease Successfully Treated with Anakinra.Q40081000
Efficacy of tocilizumab in conventional treatment-refractory adult-onset Still's disease: multicenter retrospective open-label study of thirty-four patients.Q40218234
Tocilizumab in adult-onset Still's disease: the Israeli experienceQ40221214
Tocilizumab for the treatment of adult-onset Still's disease: results from a case series.Q40235629
Tocilizumab in refractory adult Still's diseaseQ40350291
Efficacy of abatacept in a refractory case of adult-onset Still's disease.Q40358353
Fatal myocarditis in adult-onset Still disease with diffuse intravascular coagulation.Q40403433
Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in FranceQ40436579
Diagnostic value of procalcitonin measurement in febrile patients with systemic autoimmune diseases.Q40477212
Adult-onset Still disease as the cause of fever of unknown originQ40494870
Rapid responses to anakinra in patients with refractory adult-onset Still's diseaseQ40507008
Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrationsQ40518156
Serum cytokine profiles in patients with adult onset Still's diseaseQ40543910
Etanercept in the treatment of adult patients with Still's diseaseQ40578875
Epidemiological study of adult-onset Still's disease using a Japanese administrative databaseQ40630580
A case of adult onset Still's disease complicated with adult respiratory distress syndrome and disseminated intravascular coagulationQ40687328
Adult Still's disease: a multicenter survey of Japanese patients.Q40759885
A case of adult Still's disease with pulmonary hypertensionQ40765056
Adult Still's disease and inflammatory myositis.Q40810089
Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's diseaseQ40819082
Adult Still's disease: part I. Manifestations and complications in sixty-five cases in FranceQ41163072
Adult Still's disease. Part II. Management, outcome, and prognostic factorsQ41163086
Severe sore throat as a presenting symptom of adult onset Still's disease: a case series and review of the literatureQ41372194
sCD163 in AOSD: a biomarker for macrophage activation related to hyperferritinemiaQ41666895
Refractory adult-onset still disease successfully treated with abataceptQ41931873
Interleukin 18: a biomarker for differential diagnosis between adult-onset Still's disease and sepsisQ42217081
Anakinra treatment in patients with adult-onset Still's disease is fast, effective, safe and steroid sparing: experience from an uncontrolled trialQ42410300
On a Form of Chronic Joint Disease in ChildrenQ42594394
A Pilot Study on Tocilizumab for Treating Refractory Adult-Onset Still's DiseaseQ42677427
Exacerbation of adult-onset Still's disease, possibly related to elevation of serum tumor necrosis factor-alpha after etanercept administrationQ42768414
The effect of tocilizumab on preventing relapses in adult-onset Still's disease: A retrospective, single-center studyQ43507241
Infliximab in the treatment of adult Still's disease refractory to conventional therapyQ43640728
Serum S100A8/A9, but not follistatin-like protein 1 and interleukin 18, may be a useful biomarker of disease activity in adult-onset Still's disease.Q43660594
Drug-induced hemophagocytosisQ43996631
Two more cases of Still's disease and Kikuchi'sQ44137829
Anakinra in adult-onset Still's disease: long-term treatment in patients resistant to conventional therapyQ44201170
Efficacy of traditional and biologic agents in different clinical phenotypes of adult-onset Still's diseaseQ44554787
Amyloidosis in adult onset Still's diseaseQ45055909
Markedly increased IL-18 liver expression in adult-onset Still's disease-related hepatitisQ45128834
Estimated prevalence and incidence of adult Still's disease: findings by a nationwide epidemiological survey in Japan.Q45242187
Interleukin-18 as an efficient marker for remission and follow-up in patients with inactive adult-onset Still's diseaseQ45334281
Pulmonary arterial hypertension and acute respiratory distress syndrome in a patient with adult-onset stills diseaseQ47136060
Extremely High Serum Ferritin: An Instrumental Marker of Masquerading Adult-Onset Still's Disease with Hemophagocytic Syndrome.Q47156287
Efficacy of tocilizumab therapy in Korean patients with adult-onset Still's disease: a multicentre retrospective study of 22 casesQ47649993
Efficacy and safety of tocilizumab with inhibition of interleukin-6 in adult-onset Still's disease: A meta-analysis.Q49691035
Rituximab treatment for pulmonary arterial hypertension in adult-onset Still's disease.Q51037414
Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still's disease.Q51748695
Pulmonary arterial hypertension in autoimmune diseases: an analysis of 19 cases from a medical center in northern Taiwan.Q51811224
Lymph node IL-18 expression in adult-onset Still's disease.Q51824485
Complications of adult-onset Still's disease and their management.Q52586847
Autoinflammation. Management of hereditary recurrent fevers--SHARE experience.Q54252190
Association of intercellular adhesion molecule-1 with clinical manifestations and interleukin-18 in patients with active, untreated adult-onset Still's disease.Q54660855
Proinflammatory cytokine profiles in sera and pathological tissues of patients with active untreated adult onset Still's disease.Q54695048
Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes.Q54806502
Diagnostic and management of life-threatening Adult-Onset Still Disease: a French nationwide multicenter study and systematic literature review.Q55109011
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertensionQ57823897
High ferritin and low glycosylated ferritin may also be a marker of excessive macrophage activationQ58621869
The evolution of adult-onset Still disease: an observational and comparative study in a cohort of 76 Italian patientsQ64041811
Pulmonary arterial hypertension complicating adult-onset Still's diseaseQ64043572
Carpal arthritis with ankylosis in late onset still's diseaseQ67442609
Adult-onset Still's diseaseQ67790685
Serum ferritin can be useful for diagnosis in adult onset Still's diseaseQ69615281
Increased serum ferritin levels in adult Still's diseaseQ69894994
Systemic amyloidosis in a patient with adult onset Still's diseaseQ70719873
Ferritin levels and response to treatment in patients with Adult Still's diseaseQ71608995
Serum ferritin and isoferritins are tools for diagnosis of active adult Still's diseaseQ72137820
Extremely elevated serum ferritin levels in a university hospital: associated diseases and clinical significanceQ72306519
Diagnostic value of ferritin and glycosylated ferritin in adult onset Still's diseaseQ73608471
Vascular renal AA amyloidosis in adult Still's diseaseQ73621810
Interleukin-18 as a novel diagnostic marker and indicator of disease severity in adult-onset Still's diseaseQ74242469
Hyperferritinemia as a marker of Still's diseaseQ74314476
Proposal for a new set of classification criteria for adult-onset still diseaseQ78069999
The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritisQ79844555
Pulmonary hypertension in a patient with adult-onset Stills diseaseQ80001180
The levels of macrophage migration inhibitory factor as an indicator of disease activity and severity in adult-onset Still's diseaseQ80665655
Low glycosylated ferritin, a good marker for the diagnosis of hemophagocytic syndromeQ81158236
IL1-receptor antagonist anakinra provides long-lasting efficacy in the treatment of refractory adult-onset Still's diseaseQ82669504
Cytokine profiles of macrophage activation syndrome associated with rheumatic diseasesQ83192751
Glucocorticoid and cyclosporine refractory adult onset Still's disease successfully treated with tocilizumabQ83274923
IL-1 Trap rilonacept in refractory adult onset Still's diseaseQ84330833
Clinical manifestations but not cytokine profiles differentiate adult-onset Still's disease and sepsisQ84973391
Association of a mutation in LACC1 with a monogenic form of systemic juvenile idiopathic arthritisQ85309904
Serum S100A12 may be a useful biomarker of disease activity in adult-onset Still's diseaseQ85664363
Clinical manifestations of Adult-onset Still's disease presenting with erosive arthritis: Association with low levels of ferritin and Interleukin-18Q86525434
Canakinumab in a case of adult onset still's disease: efficacy only on systemic manifestationsQ87162122
Successful treatment of refractory adult-onset still disease with canakinumab: a case reportQ87343210
Steroid-sparing effects of etanercept in a patient with steroid-dependent adult-onset Still's diseaseQ87993394
Increased severity and epidermal alterations in persistent versus evanescent skin lesions in adult-onset Still diseaseQ88773149
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
adult-onset Still's diseaseQ1187697
P304page(s)603-618
P577publication date2018-10-01
P1433published inNature Reviews RheumatologyQ2107227
P1476titleMechanisms, biomarkers and targets for adult-onset Still's disease
P478volume14

Reverse relations

cites work (P2860)
Q93021023Both HLA class I and II regions identified as genome-wide significant susceptibility loci for adult-onset Still's disease in Chinese individuals
Q91872188Cysteine-Rich Angiogenic Inducer 61 Serves as a Potential Serum Biomarker for the Remission of Adult-Onset Still's Disease
Q64093140Cytomegalovirus Infection May Trigger Adult-Onset Still's Disease Onset or Relapses
Q90152839Genetic Association and Expression Correlation between Colony-Stimulating Factor 1 Gene Encoding M-CSF and Adult-Onset Still's Disease
Q90394365Macrophage activation syndrome in a patient with axial spondyloarthritis on adalimumab
Q61449155Plasma microRNA Profiles as a Potential Biomarker in Differentiating Adult-Onset Still's Disease From Sepsis
Q98467043Successful treatment of secondary macrophage activation syndrome with emapalumab in a patient with newly diagnosed adult-onset Still's disease: case report and review of the literature
Q90622281Tocilizumab-induced anaphylaxis in patients with adult-onset Still's disease and systemic juvenile idiopathic arthritis: a case-based review

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