In Vitro Selection of Specific DNA Aptamers Against the Anti-Coagulant Dabigatran Etexilate

scientific article published in Scientific Reports

In Vitro Selection of Specific DNA Aptamers Against the Anti-Coagulant Dabigatran Etexilate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-018-31327-3
P932PMC publication ID6125329
P698PubMed publication ID30185972

P50authorJürgen PoppQ21033130
Dana Cialla-MayQ56045735
Shimaa EissaQ84567386
Karina WeberQ89342205
Maher M AljohaniQ91304936
P2093author name stringOmar A Alsager
Mohammed Zourob
Raja Chinnappan
P2860cites workEmergent Bleeding in Patients Receiving Direct Oral AnticoagulantsQ26743614
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Dabigatran, bleeding, and the regulatorsQ28244581
Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activityQ28278166
2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm SocietyQ29614693
Aptamers and their biological applicationsQ30470240
RNA aptamers as reversible antagonists of coagulation factor IXa.Q33344114
Gonyautoxin 1/4 aptamers with high-affinity and high-specificity: From efficient selection to aptasensor application.Q53201395
Diluted thrombin time reliably measures low to intermediate plasma dabigatran concentrations.Q53342787
Determination of dabigatran, rivaroxaban and apixaban by ultra-performance liquid chromatography - tandem mass spectrometry (UPLC-MS/MS) and coagulation assays for therapy monitoring of novel direct oral anticoagulants.Q53468814
Nucleic acid aptamers in therapeutic anticoagulation. Technology, development and clinical applicationQ81873110
Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatranQ85232153
Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulantsQ85558713
Response to letter regarding article, "Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial aQ86047624
Direct thrombin inhibitors.Q33393692
Aptamers and the next generation of diagnostic reagentsQ33615065
Nucleic acid aptamers: clinical applications and promising new horizonsQ34028112
Thrombosis: a major contributor to global disease burden.Q34442924
Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitorQ34611004
Aptamer-based label-free impedimetric biosensor for detection of progesterone.Q35500014
Generation of an anti-Dabigatran Monoclonal Antibody and Its Use in a Highly Sensitive and Specific Enzyme-Linked Immunosorbent Assay for Serum DabigatranQ35539271
Primary and secondary prevention of cardiovascular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice GuidelinesQ35752598
UPLC-MRM Mass Spectrometry Method for Measurement of the Coagulation Inhibitors Dabigatran and Rivaroxaban in Human Plasma and Its Comparison with Functional AssaysQ35877331
Coagulation assessment with the new generation of oral anticoagulantsQ36968781
Anticoagulating obese patients in the modern era.Q37919151
New anticoagulants and antiplatelet agents: a primer for the clinical gastroenterologistQ38176801
Enzyme-linked, aptamer-based, competitive biolayer interferometry biosensor for palytoxinQ38290229
DNA aptamers selection and characterization for development of label-free impedimetric aptasensor for neurotoxin anatoxin-aQ38301673
Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures.Q38332219
Epidemiology of venous thromboembolismQ41667853
The discovery of dabigatran etexilateQ41842059
Dabigatran effects on the international normalized ratio, activated partial thromboplastin time, thrombin time, and fibrinogen: a multicenter, in vitro studyQ46176054
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectdabigatranQ419345
P304page(s)13290
P577publication date2018-09-05
P1433published inScientific ReportsQ2261792
P1476titleIn Vitro Selection of Specific DNA Aptamers Against the Anti-Coagulant Dabigatran Etexilate
P478volume8

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cites work (P2860)
Q92256794A Mini-Review: Clinical Development and Potential of Aptamers for Thrombotic Events Treatment and Monitoring
Q90334948Label-Free Fluorescent Aptasensor for Small Targets via Displacement of Groove Bound Curcumin Molecules