Serotonin 5-HT Receptor Activation Suppresses Binge Intake and the Reinforcing and Motivational Properties of High-Fat Food

scholarly article by Amanda E Price et al published 2018 in Frontiers in Pharmacology

Serotonin 5-HT Receptor Activation Suppresses Binge Intake and the Reinforcing and Motivational Properties of High-Fat Food is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FPHAR.2018.00821
P932PMC publication ID6072841
P698PubMed publication ID30100875

P50authorJonathan D HommelQ61108972
P2093author name stringKathryn A Cunningham
Noelle C Anastasio
Sonja J Stutz
Amanda E Price
P2860cites workThe neurobiological basis of binge-eating disorderQ26768570
WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activityQ28582332
Serotonin at the nexus of impulsivity and cue reactivity in cocaine addictionQ33874819
Serotonin and drug reward: focus on 5-HT2C receptorsQ34277384
5-HT2C receptor agonists: pharmacological characteristics and therapeutic potentialQ34750267
Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cuesQ35046675
Feeding and reward: perspectives from three rat models of binge eatingQ35093247
5-HT2C receptor agonists as potential drugs for the treatment of obesityQ35100828
Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptorsQ36509808
Can the reinforcing value of food be measured in bulimia nervosa?Q36553318
The prevalence and correlates of binge eating disorder in the World Health Organization World Mental Health SurveysQ36774110
Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) systemQ36818400
Effect of (-)-trans-PAT, a novel 5-HT2C receptor agonist, on intake of palatable food in miceQ37015833
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasisQ37073396
Homeostatic and hedonic signals interact in the regulation of food intakeQ37271481
Neuromedin U receptor 2 knockdown in the paraventricular nucleus modifies behavioral responses to obesogenic high-fat food and leads to increased body weight.Q37502658
Regulation of motivation for food by neuromedin U in the paraventricular nucleus and the dorsal raphe nucleusQ37553137
Variation within the serotonin (5-HT) 5-HT₂C receptor system aligns with vulnerability to cocaine cue reactivityQ37663627
A novel aminotetralin-type serotonin (5-HT) 2C receptor-specific agonist and 5-HT2A competitive antagonist/5-HT2B inverse agonist with preclinical efficacy for psychosesQ37707718
Activation of Ventral Tegmental Area 5-HT2C Receptors Reduces Incentive MotivationQ37716024
Lorcaserin: a novel serotonin 2C agonist for the treatment of obesityQ38097910
From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonistsQ38138298
Serotonin controlling feeding and satietyQ38248834
Therapeutic Potential of 5-HT2C Receptor Agonists for Addictive DisordersQ38419892
Effects of the serotonin 2C receptor agonist WAY163909 on the abuse-related effects and mesolimbic dopamine neurochemistry induced by abused stimulants in rhesus monkeys.Q38741661
Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacyQ41104016
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Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcementQ42972593
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.Q43913101
Effect of BMI and binge eating on food reward and energy intake: further evidence for a binge eating subtype of obesityQ43967832
Activation of central melanocortin pathways by fenfluramineQ44079737
Evaluation of chemically diverse 5-HT₂c receptor agonists on behaviours motivated by food and nicotine and on side effect profilesQ46240693
A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trialQ46879925
Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM studyQ47321369
Binge-eating disorder: Clinical and therapeutic advancesQ47640174
Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101.Q47767859
Hedonic hunger and binge eating among women with eating disordersQ47852933
Implicit wanting and explicit liking are markers for trait binge eating. A susceptible phenotype for overeatingQ48113155
Activation of Serotonin 2C Receptors in Dopamine Neurons Inhibits Binge-like Eating in MiceQ48574951
Binge eating in rats with limited access to vegetable shortening.Q53542215
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectserotoninQ167934
pharmacologyQ128406
P304page(s)821
P577publication date2018-01-01
P1433published inFrontiers in PharmacologyQ2681208
P1476titleSerotonin 5-HT Receptor Activation Suppresses Binge Intake and the Reinforcing and Motivational Properties of High-Fat Food
P478volume9

Reverse relations

cites work (P2860)
Q93187110Anterior insula activity regulates the associated behaviors of high fat food binge intake and cue reactivity in male rats
Q64259239Binge-Type Eating in Rats is Facilitated by Neuromedin U Receptor 2 in the Nucleus Accumbens and Ventral Tegmental Area
Q90018343Convergent neural connectivity in motor impulsivity and high-fat food binge-like eating in male Sprague-Dawley rats
Q64256903Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HT) Receptor Agonists in the Ventral Tegmental Area (VTA) Inhibit Ghrelin-Stimulated Appetitive Reward
Q60305402Pimavanserin and Lorcaserin Attenuate Measures of Binge Eating in Male Sprague-Dawley Rats

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