Blocking T-cell costimulation in transplantation: opportunities and challenges

scientific article published on 01 February 2000

Blocking T-cell costimulation in transplantation: opportunities and challenges is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

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P356DOI10.1046/J.1537-2995.2000.40020139.X
P698PubMed publication ID10685997

P50authorXian C. LiQ38548815
P2093author name stringT B Strom
P2860cites workCD40 AND CD154 IN CELL-MEDIATED IMMUNITYQ22255634
CD28/B7 system of T cell costimulationQ24313544
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulationQ24678846
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4Q28284177
B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalphaQ30807749
Finally, CTLA4Ig graduates to the clinicQ33852345
Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation moleculeQ34298838
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.Q34300766
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primatesQ34433847
TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activationQ36368029
Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.Q37382702
Signals and signs for lymphocyte responsesQ40620206
The CD40 pathway in allograft rejection, acceptance, and toleranceQ41642375
TRANCE-RANK, a new signal pathway involved in lymphocyte development and T cell activationQ42944002
CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.Q45878144
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.Q54308518
Infectious tolerance.Q55068093
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathwaysQ56908985
Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft toleranceQ57202280
P433issue2
P304page(s)139-142
P577publication date2000-02-01
P1433published inTransfusionQ15758500
P1476titleBlocking T-cell costimulation in transplantation: opportunities and challenges
P478volume40

Reverse relations

cites work (P2860)
Q52005546Islet Allograft Rejection in Nonobese Diabetic Mice Involves the Common γ-Chain and CD28/CD154-Dependent and -Independent Mechanisms
Q35146722Negative T cell costimulation and islet tolerance.
Q37254050On CD28/CD40 ligand costimulation, common gamma-chain signals, and the alloimmune response

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