A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of α-Synuclein and β-Synuclein

A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of α-Synuclein and β-Synuclein is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI300558Q
P698PubMed publication ID23003198

P50authorGian Gaetano TartagliaQ43101358
Cintia RoodveldtQ47151783
Chris DobsonQ1982431
Michele VendruscoloQ28322492
P2093author name stringAugust Andersson
Adahir Labrador-Garrido
Alexander K. Buell
Erwin J. De Genst
P433issue44
P407language of work or nameEnglishQ1860
P921main subjectSynucleinQ24767155
P1104number of pages8
P304page(s)8771-8778
P577publication date2012-10-22
P1433published inBiochemistryQ764876
P1476titleA Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of α-Synuclein and β-Synuclein
P478volume51

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cites work (P2860)
Q37216202A label-free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence
Q42285864A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues
Q34447530A relationship between the transient structure in the monomeric state and the aggregation propensities of α-synuclein and β-synuclein
Q47839926Alternative Splicing of Alpha- and Beta-Synuclein Genes Plays Differential Roles in Synucleinopathies.
Q64869800Multi-Pronged Interactions Underlie Inhibition of α-Synuclein Aggregation by β-Synuclein
Q46464490Potential of mean force and molecular dynamics study on the transient interactions between α and β synuclein that drive inhibition of α-synuclein aggregation
Q35043731Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation
Q35549078Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.
Q37593239The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction.
Q36749469The loss of inhibitory C-terminal conformations in disease associated P123H β-synuclein
Q36205306Toxic effects of human and rodent variants of alpha-synuclein in vivo.
Q36174650Unveiling transient protein-protein interactions that modulate inhibition of alpha-synuclein aggregation by beta-synuclein, a pre-synaptic protein that co-localizes with alpha-synuclein
Q37442810Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins
Q42374822β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.

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