Thirty-eight-negative kinase 1 (TNK1) facilitates TNFα-induced apoptosis by blocking NF-κB activation

scholarly article by N Azoitei et al published 30 April 2007 in Oncogene

Thirty-eight-negative kinase 1 (TNK1) facilitates TNFα-induced apoptosis by blocking NF-κB activation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.ONC.1210476
P698PubMed publication ID17471239

P50authorSimone FuldaQ21264686
P2093author name stringG Adler
A Brey
T Seufferlein
T Busch
N Azoitei
P2860cites workCharacterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1Q22254432
Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)Q24297420
RANK is essential for osteoclast and lymph node developmentQ24598872
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosisQ24608044
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
Mechanisms of caspase activationQ28187994
Signaling to NF-kappaBQ29547844
The pathophysiology of mitochondrial cell deathQ29547893
An essential role for NF-kappaB in preventing TNF-alpha-induced cell deathQ29614707
NF-kappaB at the crossroads of life and deathQ29619302
Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatmentQ33200418
Tumor necrosis factor signaling.Q34185821
Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosisQ35189463
The protein structures that shape caspase activity, specificity, activation and inhibitionQ35902423
A20 inhibits NF-kappaB activation by dual ubiquitin-editing functionsQ36011021
Tumor necrosis factor-alpha activation of nuclear transcription factor-kappaB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of Ikappa Balpha.Q38331977
Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavageQ40418357
Trichostatin A (TSA) sensitizes the human prostatic cancer cell line DU145 to death receptor ligands treatmentQ40431856
Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.Q40571746
Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-kappa B activation and IkappaBalpha phosphorylation. Relationship with down-regulation of TNF receptorsQ40725886
Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factorQ42943618
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinaseQ44414477
Tumor Necrosis Factor and the p55TNF Receptor Are Required for Optimal Development of the Marginal Sinus and for Migration of Follicular Dendritic Cell Precursors into Splenic FolliclesQ62819796
Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alphaQ71513462
The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinaseQ77927046
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)6536-6545
P577publication date2007-04-30
P1433published inOncogeneQ1568657
P1476titleThirty-eight-negative kinase 1 (TNK1) facilitates TNFα-induced apoptosis by blocking NF-κB activation
P478volume26

Reverse relations

cites work (P2860)
Q37320368Functional characterization of the murine Tnk1 promoter
Q35014417Gene expression profiles in human and mouse primary cells provide new insights into the differential actions of vitamin D3 metabolites
Q24629875Genetics of late-onset Alzheimer's disease: update from the alzgene database and analysis of shared pathways
Q24655873Genome-wide association studies in Alzheimer's disease
Q30502529High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells
Q43187908Identification of activated Tnk1 kinase in Hodgkin's lymphoma
Q39793134Identification of protein tyrosine kinases with oncogenic potential using a retroviral insertion mutagenesis screen
Q28115758Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
Q57463602Intestinal hyperpermeability: a gateway to multi-organ failure?
Q35006333Regulation of ack-family nonreceptor tyrosine kinases
Q48253084Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease
Q49887894Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products.
Q31153544The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data
Q57463620Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure
Q37779009Tnk1/Kos1: a novel tumor suppressor

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