Biogenesis of secretory granules in the trans-Golgi network of neuroendocrine and endocrine cells

scientific article published on 01 August 1998

Biogenesis of secretory granules in the trans-Golgi network of neuroendocrine and endocrine cells is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0167-4889(98)00059-7
P932PMC publication ID7126647
P698PubMed publication ID9714820

P50authorSharon ToozeQ21264645
P2093author name stringSharon A Tooze
P2860cites workHuman ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene familyQ24312818
Calcium- and pH-dependent aggregation and membrane association of the precursor of the prohormone convertase PC2Q24314481
Proteolytic processing of pro-ACTH/endorphin begins in the Golgi complex of pituitary corticotropes and AtT-20 cellsQ69356258
The trans-most cisternae of the Golgi complex: a compartment for sorting of secretory and plasma membrane proteinsQ69813869
Secretory granule content proteins and the luminal domains of granule membrane proteins aggregate in vitro at mildly acidic pHQ70870919
Mannose 6-phosphate receptors and ADP-ribosylation factors cooperate for high affinity interaction of the AP-1 Golgi assembly proteins with membranesQ70915222
A role for ADP-ribosylation factor 1, but not COP I, in secretory vesicle biogenesis from the trans-Golgi networkQ71513453
A chimeric proinsulin-CD5 protein expressed in AtT-20 cells is directed to the cell surface via the constitutive pathwayQ71708832
Formation of the insulin-containing secretory granule core occurs within immature beta-granulesQ72135866
Novel function of phosphatidylinositol 4,5-bisphosphate as a cofactor for brain membrane phospholipase DQ72135980
The disulfide bond in chromogranin B, which is essential for its sorting to secretory granules, is not required for its aggregation in the trans-Golgi networkQ72180519
pH-dependent interaction of an intraluminal loop of inositol 1,4,5-trisphosphate receptor with chromogranin AQ72315455
pH-dependent interaction of chromogranin A with integral membrane proteins of secretory vesicle including 260-kDa protein reactive to inositol 1,4,5-triphosphate receptor antibodyQ72376437
The amino-terminal sequence of pro-opiomelanocortin directs intracellular targeting to the regulated secretory pathwayQ72715788
Effects of acid phospholipids on nucleotide exchange properties of ADP-ribosylation factor 1. Evidence for specific interaction with phosphatidylinositol 4,5-bisphosphateQ72808716
Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat miceQ73824742
Trimeric G proteins and vesicle formationQ75294190
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.Q53200160
Protein discharge from immature secretory granules displays both regulated and constitutive characteristicsQ54380432
Requirement for GTP hydrolysis in the formation of secretory vesiclesQ57269837
Phospholipase D: a downstream effector of ARF in granulocytesQ57956412
Ringing necks with dynaminQ60073639
Cell type-specific sorting of neuropeptides: a mechanism to modulate peptide composition of large dense-core vesiclesQ60760481
Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesiclesQ68956740
Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) miceQ24317472
Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activityQ24336776
The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphataseQ24336782
The primary structure of human secretogranin II, a widespread tyrosine-sulfated secretory granule protein that exhibits low pH- and calcium-induced aggregationQ24339539
ICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granulesQ24563069
Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furinQ24568252
Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.Q27930134
An essential role for a phospholipid transfer protein in yeast Golgi functionQ27938456
The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphataseQ28118769
A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminalsQ28272772
Carboxypeptidase EQ28283622
The granin (chromogranin/secretogranin) familyQ28284590
Arf proteins: the membrane traffic police?Q28302542
A presynaptic inositol-5-phosphataseQ28565411
Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitorsQ28567654
Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranesQ28583729
Mannose 6-phosphate receptors in sorting and transport of lysosomal enzymesQ30417552
Rapid endocytosis coupled to exocytosis in adrenal chromaffin cells involves Ca2+, GTP, and dynamin but not clathrinQ33969084
Use of a synthetic peptide antigen to generate antisera reactive with a proteolytic processing site in native human proinsulin: demonstration of cleavage within clathrin-coated (pro)secretory vesiclesQ34343129
Distinct coated vesicles labeled for p200 bud from trans-Golgi network membranes.Q34511811
The oculocerebrorenal syndrome gene product is a 105-kD protein localized to the Golgi complexQ35644500
The exocrine protein trypsinogen is targeted into the secretory granules of an endocrine cell line: studies by gene transferQ36212613
Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesiclesQ36216775
Sorting within the regulated secretory pathway occurs in the trans-Golgi networkQ36222442
A cytosolic complex of p62 and rab6 associates with TGN38/41 and is involved in budding of exocytic vesicles from the trans-Golgi networkQ36232575
Prohormone processing in the trans-Golgi network: endoproteolytic cleavage of prosomatostatin and formation of nascent secretory vesicles in permeabilized cellsQ36233508
Distinct molecular mechanisms for protein sorting within immature secretory granules of pancreatic beta-cellsQ36234350
pH-independent and -dependent cleavage of proinsulin in the same secretory vesicleQ36234623
HVEM tomography of the trans-Golgi network: structural insights and identification of a lace-like vesicle coatQ36234682
Transport via the regulated secretory pathway in semi-intact PC12 cells: role of intra-cisternal calcium and pH in the transport and sorting of secretogranin II.Q36234806
Association of a dynamin-like protein with the Golgi apparatus in mammalian cells.Q36236862
Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptorQ36237417
Essential role of the disulfide-bonded loop of chromogranin B for sorting to secretory granules is revealed by expression of a deletion mutant in the absence of endogenous granin synthesisQ36255101
Phosphatidylinositol 3-kinase is required for the formation of constitutive transport vesicles from the TGNQ36273833
Differential sorting of lysosomal enzymes out of the regulated secretory pathway in pancreatic beta-cellsQ36274102
Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi networkQ36276378
Intermediates in the constitutive and regulated secretory pathways released in vitro from semi-intact cellsQ36531322
Protein targeting via the "constitutive-like" secretory pathway in isolated pancreatic islets: passive sorting in the immature granule compartmentQ36531699
What the granins tell us about the formation of secretory granules in neuroendocrine cellsQ36724876
Clathrin-immunoreactive sites in the Golgi apparatus are concentrated at the trans pole in polypeptide hormone-secreting cellsQ37528300
An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surfaceQ37623766
Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free systemQ37629098
Chromogranin B (secretogranin I) promotes sorting to the regulated secretory pathway of processing intermediates derived from a peptide hormone precursorQ37639506
ADP-ribosylation factor-1 stimulates formation of nascent secretory vesicles from the trans-Golgi network of endocrine cellsQ38360636
A casein kinase II phosphorylation site in the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor determines the high affinity interaction of the AP-1 Golgi assembly proteins with membranesQ38362519
The insulin factory: a tour of the plant surroundings and a visit to the assembly line. The Minkowski lecture 1973 revisitedQ38591483
Biosynthetic protein transport and sorting by the endoplasmic reticulum and GolgiQ39664981
Constitutive and regulated secretion of proteinsQ39683816
Regulated secretion. Helper proteins for neuroendocrine secretionQ40544514
The role of clathrin, adaptors and dynamin in endocytosisQ40647427
Sorting and processing of secretory proteinsQ40744676
Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tailQ40790070
Phosphoinositides as regulators in membrane trafficQ40968891
Dynamin and receptor-mediated endocytosisQ41017094
Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteinsQ41020937
The role of ADP-ribosylation factor and phospholipase D in adaptor recruitmentQ41090845
Interaction of furin in immature secretory granules from neuroendocrine cells with the AP-1 adaptor complex is modulated by casein kinase II phosphorylationQ41093806
Molecular mechanisms in synaptic vesicle endocytosis and recyclingQ41094245
pH-dependent processing of secretogranin II by the endopeptidase PC2 in isolated immature secretory granules.Q41142545
The in vitro generation of post-Golgi vesicles carrying viral envelope glycoproteins requires an ARF-like GTP-binding protein and a protein kinase C associated with the Golgi apparatusQ41185133
The AP-1 adaptor complex binds to immature secretory granules from PC12 cells, and is regulated by ADP-ribosylation factorQ41233302
A role for phosphatidylinositol transfer protein in secretory vesicle formationQ41283307
Cysteine proteinases in GH4C1 cells, a rat pituitary tumor cell line, are secreted by the constitutive and regulated secretory pathwaysQ41315680
Identification of the sorting signal motif within pro-opiomelanocortin for the regulated secretory pathwayQ41350449
Direct measurement of trans-Golgi pH in living cells and regulation by second messengersQ41360787
An elevation of cytosolic protein phosphorylation modulates trimeric G-protein regulation of secretory vesicle formation from the trans-Golgi networkQ41436432
Clathrin-coated vesicular transport of secretory proteins during the formation of ACTH-containing secretory granules in AtT20 cellsQ41508036
ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activityQ41508317
Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cellsQ41534065
An antibody specific for an endoproteolytic cleavage site provides evidence that pro-opiomelanocortin is packaged into secretory granules in AtT20 cells before its cleavageQ41541196
Multiple trimeric G-proteins on the trans-Golgi network exert stimulatory and inhibitory effects on secretory vesicle formation.Q41542399
Protein secretion: puzzling receptorsQ41564981
Chromogranin B (secretogranin I), a secretory protein of the regulated pathway, is also present in a tightly membrane-associated form in PC12 cellsQ41639073
Milieu-induced, selective aggregation of regulated secretory proteins in the trans-Golgi networkQ41654828
A targeting sequence for dense secretory granules resides in the active renin protein moiety of human preproreninQ41713300
Cell-free protein sorting to the regulated and constitutive secretory pathwaysQ41740710
The role of a low pH intracellular compartment in the processing, storage, and secretion of ACTH and endorphinQ41911881
Chloroquine diverts ACTH from a regulated to a constitutive secretory pathway in AtT-20 cellsQ41921642
Protein transport. Greasing the Golgi budding machineQ47310033
Phosphoinositide 3-kinases and membrane trafficQ47986385
Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid.Q48139459
GTP hydrolysis by ADP-ribosylation factor is dependent on both an ADP-ribosylation factor GTPase-activating protein and acid phospholipidsQ48141237
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding proteinQ48268447
Pathways of protein secretion in eukaryotesQ48446174
Essential role for diacylglycerol in protein transport from the yeast Golgi complex.Q48721596
Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cellsQ49111483
P433issue1-2
P921main subjectneuroendocrinologyQ1335366
P304page(s)231-244
P577publication date1998-08-01
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleBiogenesis of secretory granules in the trans-Golgi network of neuroendocrine and endocrine cells
P478volume1404