Inactive matrix Gla protein is a novel circulating biomarker predicting retinal arteriolar narrowing in humans

scientific article published in Scientific Reports

Inactive matrix Gla protein is a novel circulating biomarker predicting retinal arteriolar narrowing in humans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-018-33257-6
P932PMC publication ID6180139
P698PubMed publication ID30305657

P50authorLutgarde ThijsQ55174102
Karel AllegaertQ57314006
Blerim MujajQ64927383
Jan A. StaessenQ37390604
Nicholas CauwenberghsQ47705498
P2093author name stringTatiana Kuznetsova
Zhen-Yu Zhang
Cees Vermeer
Fang-Fei Wei
Qi-Fang Huang
Wen-Yi Yang
Harry A J Struijker-Boudier
Peter Verhamme
Sander Trenson
Karel Van Keer
P2860cites workA novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammationQ26850196
Extracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucomaQ26851287
Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulationQ27334619
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjectsQ28300546
Characterization of gene expression in human trabecular meshwork using single-pass sequencing of 1060 clonesQ30951741
Measurement of plasma vitamin K1 (phylloquinone) and K2 (menaquinones-4 and -7) using HPLC-tandem mass spectrometry.Q33466670
Retinal microvascular abnormalities and risk of lacunar stroke: Atherosclerosis Risk in Communities StudyQ33949587
Matrix GLA protein function in human trabecular meshwork cells: inhibition of BMP2-induced calcification processQ35070274
A Novel Mgp-Cre Knock-In Mouse Reveals an Anticalcification/Antistiffness Candidate Gene in the Trabecular Meshwork and Peripapillary Scleral RegionQ35521527
Prospective cohort study of retinal vessel diameters and risk of hypertensionQ35837227
Vitamin K Dependent Protection of Renal Function in Multi-ethnic Population StudiesQ36645022
The effect of menaquinone-7 supplementation on circulating species of matrix Gla protein.Q51171004
Epidemiological and histological findings implicate matrix Gla protein in diastolic left ventricular dysfunction.Q52359177
Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.Q53611739
Human trabecular meshwork cells express BMP antagonist mRNAs and proteins.Q53786530
Inactive Matrix Gla Protein Is Causally Related to Adverse Health OutcomesQ57085312
General Caliber of the Retinal Arteries Expressed as the Equivalent width of the Central Retinal ArteryQ69746533
Matrix Gla-protein: the calcification inhibitor in need of vitamin KQ82234682
Systemic arterial stiffness in patients with pseudoexfoliation glaucomaQ86694425
Conventional and Ambulatory Blood Pressure as Predictors of Retinal Arteriolar NarrowingQ37116384
Retinal Vessel Diameters and Their Relationship with Cardiovascular Risk and All-Cause Mortality in the Inter99 Eye Study: A 15-Year Follow-UpQ37521559
Retinal microvasculature as a model to study the manifestations of hypertension.Q38050429
Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.Q38224185
The Trabecular Meshwork: A Basic Review of Form and FunctionQ38263876
Glia-induced neuronal differentiation by transcriptional regulationQ38300652
Bone morphogenetic protein-4 induces upregulation of Cav3.1 Ca²⁺ channels in HL-1 atrial myocytesQ39025756
Evidence of retinal vascular narrowing in glaucomatous eyes in an Asian populationQ39858121
Revised formulas for summarizing retinal vessel diametersQ40555668
Retinal arteriolar narrowing and risk of coronary heart disease in men and women. The Atherosclerosis Risk in Communities StudyQ40655684
Matrix GLA protein, a regulatory protein for bone morphogenetic protein-2.Q40763871
Renal glomerular dysfunction in relation to retinal arteriolar narrowing and high pulse pressure in seniors.Q41130831
Inactive Matrix Gla-Protein Is Associated With Arterial Stiffness in an Adult Population-Based StudyQ41729759
Negative and positive auto-regulation of BMP expression in early eye developmentQ41865714
Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesisQ42199745
Bone morphogenetic protein-4 and bone morphogenetic protein receptors expressions in the adult rat eyeQ42355988
Carotid artery elasticity and baroreflex sensitivity in patients with glaucomaQ42645082
Retinal vessel diameter and open-angle glaucoma: the Blue Mountains Eye StudyQ42647031
Application of the Bland-Altman plot for interpretation of method-comparison studies: a critical investigation of its practice.Q43972522
Bone morphogenetic protein-4 mediates cardiac hypertrophy, apoptosis, and fibrosis in experimentally pathological cardiac hypertrophyQ44211351
Retinal microvascular abnormalities and 10-year cardiovascular mortality: a population-based case-control studyQ44443119
Retinal arteriolar diameter and risk for hypertension.Q44768406
Regulation of bone morphogenetic protein-4 by matrix GLA protein in vascular endothelial cells involves activin-like kinase receptor 1.Q46071755
Relation of atherosclerotic changes in retinal arteries to the extent of coronary artery diseaseQ46743733
Desphospho-uncarboxylated matrix Gla protein is a novel circulating biomarker predicting deterioration of renal function in the general population.Q47676686
Microarray analysis of gene expression in human donor scleraQ47889433
Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities StudyQ48567624
A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies.Q49221804
Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species.Q49811566
Fundus Densitometry Findings Suggest Optic Disc Hemorrhages in Primary Open-Angle Glaucoma Have an Arterial Origin.Q50060018
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
P304page(s)15088
P577publication date2018-10-10
P1433published inScientific ReportsQ2261792
P1476titleInactive matrix Gla protein is a novel circulating biomarker predicting retinal arteriolar narrowing in humans
P478volume8

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cites work (P2860)
Q101121184Generation of a Matrix Gla (Mgp) floxed mouse, followed by conditional knockout, uncovers a new Mgp function in the eye
Q99403369Inactive matrix Gla protein is elevated in patients with inflammatory bowel disease
Q89857321Inactive matrix gla protein plasma levels are associated with peripheral neuropathy in Type 2 diabetes
Q91682922Retinal Microvasculature in Relation to Central Hemodynamics in a Flemish Population
Q90046444Vitamin K-Dependent Matrix Gla Protein as Multifaceted Protector of Vascular and Tissue Integrity