| scholarly article | Q13442814 |
| P50 | author | Michael D Burkart | Q59820694 |
| P2093 | author name string | Aochiu Chen | |
| Rebecca N Re | |||
| P2860 | cites work | THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS | Q22255655 |
| Visualizing the chain-flipping mechanism in fatty-acid biosynthesis | Q27339761 | ||
| Molecular basis of triclosan activity | Q27617904 | ||
| Inhibitor binding studies on enoyl reductase reveal conformational changes related to substrate recognition | Q27619988 | ||
| Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis | Q27620639 | ||
| Refined structures of beta-ketoacyl-acyl carrier protein synthase III | Q27630568 | ||
| Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis | Q27635477 | ||
| X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site | Q27639153 | ||
| Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway | Q27639955 | ||
| A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chains | Q27648924 | ||
| Inhibition Kinetics and Emodin Cocrystal Structure of a Type II Polyketide Ketoreductase † , ‡ | Q27649562 | ||
| Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2) | Q27654649 | ||
| Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme | Q27656925 | ||
| Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase β Subunit of Streptomyces coelicolor , | Q27663890 | ||
| The Determinants of Activity and Specificity in Actinorhodin Type II Polyketide Ketoreductase | Q27679936 | ||
| Trapping the dynamic acyl carrier protein in fatty acid biosynthesis | Q27681033 | ||
| The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component | Q27730253 | ||
| Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site | Q27733371 | ||
| Using modern tools to probe the structure-function relationship of fatty acid synthases | Q28080940 | ||
| Mechanism of triclosan inhibition of bacterial fatty acid synthesis | Q28140952 | ||
| Polyketide chain length control by chain length factor | Q28209671 | ||
| Evolutionary implications of bacterial polyketide synthases | Q28256873 | ||
| The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization | Q28267747 | ||
| An antibiotic factory caught in action | Q28275079 | ||
| Dynamics of folded proteins | Q28287584 | ||
| Identification and substrate specificity of beta -ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis | Q28486928 | ||
| The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life | Q28659329 | ||
| Manipulating fatty acid biosynthesis in microalgae for biofuel through protein-protein interactions | Q28727825 | ||
| Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity | Q29614981 | ||
| Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases | Q33737908 | ||
| Reversible labeling of native and fusion-protein motifs | Q34025257 | ||
| Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis | Q34063644 | ||
| Synopsis of some recent tactical application of bioisosteres in drug design | Q34171394 | ||
| Beta-ketoacyl-acyl carrier protein synthase II of Escherichia coli. Evidence for function in the thermal regulation of fatty acid synthesis | Q34274766 | ||
| Inhibitors of fatty acid synthesis as antimicrobial chemotherapeutics | Q34647478 | ||
| Modeling linear and cyclic PKS intermediates through atom replacement. | Q34778268 | ||
| Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant | Q35589890 | ||
| Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase | Q35921735 | ||
| On the enzymatic synthesis of unsaturated fatty acids in Escherichia coli | Q35978002 | ||
| Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis. | Q36607621 | ||
| Chemoenzymatic exchange of phosphopantetheine on protein and peptide | Q36695649 | ||
| Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork | Q36724719 | ||
| Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli | Q36760116 | ||
| Solution structures of spinach acyl carrier protein with decanoate and stearate | Q36870133 | ||
| Regulation of fatty acid metabolism in bacteria. | Q36962272 | ||
| Biosynthesis of aromatic polyketides in bacteria | Q37416691 | ||
| Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis | Q37482878 | ||
| Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature | Q37769021 | ||
| Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals | Q37807651 | ||
| Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents | Q38124842 | ||
| Using chemical shift perturbation to characterise ligand binding | Q38130403 | ||
| Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering | Q38264138 | ||
| Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL | Q40718758 | ||
| Dehydratase-specific probes for fatty acid and polyketide synthases | Q40778981 | ||
| Thioesterases I and II of Escherichia coli. Hydrolysis of native acyl-acyl carrier protein thioesters | Q40922562 | ||
| Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein. | Q41677094 | ||
| Trapping of the Enoyl-Acyl Carrier Protein Reductase-Acyl Carrier Protein Interaction | Q41699863 | ||
| Binding and "pKa" modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein | Q41766335 | ||
| Probing the Substrate Specificity and Protein-Protein Interactions of the E. coli Fatty Acid Dehydratase, FabA. | Q41906454 | ||
| Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase | Q42177217 | ||
| The crystal structure of the actIII actinorhodin polyketide reductase: proposed mechanism for ACP and polyketide binding | Q42637301 | ||
| Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases. | Q42957688 | ||
| Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity | Q43069253 | ||
| The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa. | Q45061784 | ||
| Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase | Q45114750 | ||
| Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits | Q46151499 | ||
| One-pot chemo-enzymatic synthesis of reporter-modified proteins | Q46262429 | ||
| Reconstitution of a Type II Polyketide Synthase Catalyzing Polyene Formation | Q47266737 | ||
| Bifunctionality of ActIV as a Cyclase-Thioesterase Revealed by in Vitro Reconstitution of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2). | Q51297880 | ||
| An Oxetane-Based Polyketide Surrogate To Probe Substrate Binding in a Polyketide Synthase. | Q52331089 | ||
| Biosynthetic gene cluster of the non-ribosomally synthesized cyclodepsipeptide skyllamycin: deciphering unprecedented ways of unusual hydroxylation reactions. | Q52896701 | ||
| New Simocyclinones: Surprising Evolutionary and Biosynthetic Insights. | Q53431393 | ||
| Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis. | Q54449796 | ||
| Structural studies of fatty acyl-(acyl carrier protein) thioesters reveal a hydrophobic binding cavity that can expand to fit longer substrates. | Q54453196 | ||
| A chain initiation factor common to both modular and aromatic polyketide synthases | Q60301879 | ||
| Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor. | Q64967073 | ||
| Beta-hydroxydecanoyl thioester dehydrase. Studies on molecular structure and active site | Q69890778 | ||
| Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases | Q74248709 | ||
| Tuning of acyl-ACP thioesterase activity directed for tailored fatty acid synthesis | Q87849957 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1029-1045 | |
| P577 | publication date | 2018-10-01 | |
| P1433 | published in | Natural Product Reports | Q2376904 |
| P1476 | title | Type II fatty acid and polyketide synthases: deciphering protein-protein and protein-substrate interactions | |
| P478 | volume | 35 |
| Q90611549 | A Light-Activated Acyl Carrier Protein "Trap" for Intermediate Capture in Type II Iterative Polyketide Biocatalysis |
| Q90227921 | Actinomycete-Derived Polyketides as a Source of Antibiotics and Lead Structures for the Development of New Antimicrobial Drugs |
| Q91708366 | Gating mechanism of elongating β-ketoacyl-ACP synthases |
| Q91512398 | Revisiting metabolic engineering strategies for microbial synthesis of oleochemicals |
| Q94521790 | Structural basis for selectivity in a highly reducing type II polyketide synthase |
| Q97423711 | Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis |
| Q64052017 | Tracking carrier protein motions with Raman spectroscopy |
| Q91771566 | Type I fatty acid synthase trapped in the octanoyl-bound state |
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