A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease

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A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/OPTH.S175065
P953full work available at URLhttps://www.dovepress.com/a-phase-iiiii-randomized-double-masked-vehicle-controlled-dose-ranging-peer-reviewed-article-OPTH
P932PMC publication ID6174300
P698PubMed publication ID30323548

P50authorSidney WeissQ57095093
P2093author name stringJoseph Tauber
Barry A Schechter
Robert Smyth-Medina
Melissa M Toyos
Jason Bacharach
Jodi I Luchs
P2860cites workControlled ocular drug delivery with nanomicellesQ27012087
Prevalence of dry eye syndrome among US womenQ28196875
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin AQ28316169
Prevalence of dry eye disease among US men: estimates from the Physicians' Health StudiesQ33720070
Aging and dry eye diseaseQ34273593
Dry eye as a mucosal autoimmune diseaseQ34647761
TFOS DEWS II pathophysiology reportQ38652987
TFOS DEWS II Epidemiology ReportQ38652994
TFOS DEWS II Definition and Classification Report.Q38665717
Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial effortsQ39185845
TFOS DEWS II Management and Therapy ReportQ39453364
Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes.Q40948258
Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. CsA Phase 3 Study GroupQ41730611
The Relationship between Habitual Patient-Reported Symptoms and Clinical Signs among Patients with Dry Eye of Varying SeverityQ44631963
Antiinflammatory therapy for dry eye.Q44763839
Efficacy and safety of 0.1% cyclosporine A cationic emulsion in the treatment of severe dry eye disease: a multicenter randomized trial.Q53620228
A randomized study of the efficacy and safety of 0.1% cyclosporine A cationic emulsion in treatment of moderate to severe dry eye.Q54222666
Analysis of topical cyclosporine treatment of patients with dry eye syndrome: effect on conjunctival lymphocytesQ73180482
Goblet cell numbers and epithelial proliferation in the conjunctiva of patients with dry eye syndrome treated with cyclosporineQ77729873
Development and validation of a short global dry eye symptom indexQ79657699
Distribution of conjunctival HLA-DR expression and the pathogenesis of damage in early dry eyesQ81357274
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P2507corrigendum / erratumErratum: A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease [Corrigendum]Q60302035
Erratum: A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease [Corrigendum]Q61810142
P407language of work or nameEnglishQ1860
P921main subjecteye diseaseQ3041498
P304page(s)1921-1929
P577publication date2018-10-02
P1433published inClinical OphthalmologyQ5133782
P1476titleA Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease
P478volume12

Reverse relations

cites work (P2860)
Q89939043A Review of Topical Cyclosporine A Formulations-A Disease-Modifying Agent for Keratoconjunctivitis Sicca
Q92442286Advances in dry eye disease treatment
Q91885064Effect of OTX-101, a Novel Nanomicellar Formulation of Cyclosporine A, on Corneal Staining in Patients With Keratoconjunctivitis Sicca: A Pooled Analysis of Phase 2b/3 and Phase 3 Studies
Q89536542Managing Dry Eye Disease and Facilitating Realistic Patient Expectations: A Review and Appraisal of Current Therapies
Q92246579Ocular Distribution of Cyclosporine Following Topical Administration of OTX-101 in New Zealand White Rabbits
Q91905513Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease

main subject (P921)
Q60302035Erratum: A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease [Corrigendum]
Q61810142Erratum: A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease [Corrigendum]

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