Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients

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Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00134-007-0722-Z
P698PubMed publication ID17558494

P50authorJürgen SchölmerichQ1717698
Gerhard RoglerQ64750687
Hans H HerfarthQ88930936
Julia BrenmoehlQ96681059
P2093author name stringStefan Schreiber
Jochen Hampe
Gerd Schmitz
Ernst Holler
Thomas Glück
Stefan Barlage
Franz Audebert
Dieter Froehlich
P2860cites workA frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaBQ24290546
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detectionQ24292675
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognitionQ24306842
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's diseaseQ28201834
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammationQ30819243
APACHE II, data accuracy and outcome predictionQ31931831
APACHE II and ISS scores as predictors of nosocomial infections in trauma patientsQ33589999
Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluationQ33833610
The gastrointestinal tract as a barrier in sepsisQ33850295
Genetic markers in sepsisQ34147947
Epidemiology of sepsis: an updateQ34303872
Pathophysiology of sepsis.Q34555784
Intestinal epithelial hyperpermeability: update on the pathogenesis of gut mucosal barrier dysfunction in critical illnessQ35092410
Gastrointestinal disorders of the critically ill. Bacterial translocation in the gut.Q35134564
Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapyQ35217223
Genetics of sepsis and pneumoniaQ35542876
Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitisQ35596103
Advances in sepsis therapyQ35732033
Innate immunity of the gut: mucosal defense in health and diseaseQ35751081
Genetic determinants of the inflammatory responseQ35896053
Genetic polymorphisms predicting the outcome of bone marrow transplantsQ35964779
Year in review in intensive care medicine, 2004. I. Respiratory failure, infection, and sepsisQ35988821
Innate immunity and mucosal bacterial interactions in the intestineQ36036431
Update in inflammatory bowel disease pathogenesisQ36036554
Year in review in intensive care medicine, 2004. III. Outcome, ICU organisation, scoring, quality of life, ethics, psychological problems and communication in the ICU, immunity and hemodynamics during sepsis, pediatric and neonatal critical care, exQ36047216
A comparison of the Ranson, Glasgow, and APACHE II scoring systems to a multiple organ system score in predicting patient outcome in pancreatitisQ36048895
New insight into the pathogenesis of sepsis and the sepsis syndromeQ36084652
Genetic polymorphisms in sepsisQ36109267
The role of gut-associated lymphoid tissues and mucosal defenceQ36118690
Intestinal permeability and systemic infections in critically ill patients: effect of glutamine.Q36125645
The international sepsis forum consensus conference on definitions of infection in the intensive care unitQ36186269
Monocytes/macrophages and sepsisQ36337625
Bacterial sepsis and chemokinesQ36384823
Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injuryQ36399486
NF-kappa B activation as a pathological mechanism of septic shock and inflammationQ36419091
New insights into cellular mechanisms during sepsisQ36499754
Severity of illness: APACHE II analysis of an ICU populationQ36829588
Ischemic intestinal complications in patients with burnsQ37671915
TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre studyQ38334675
Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trialsQ38644282
Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantationQ40516766
Stool Carriage, Clinical Isolation, and Mortality During an Outbreak of Vancomycin-Resistant Enterococci in Hospitalized Medical and/or Surgical PatientsQ43524222
Definitions for sepsis and organ failure.Q45341073
Effect of various genetic polymorphisms on the incidence and outcome of severe sepsisQ46917478
Translocation of enteric bacteria in humans.Q54654975
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populationsQ57436454
Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB ActivationQ59383486
SAPS�II revisitedQ61649254
The prevalence of gut translocation in humansQ72164347
A comparison of predictive outcomes of APACHE II and SAPS II in a surgical intensive care unitQ74600780
Interferon-gamma gene polymorphisms and the development of sepsis in patients with traumaQ74758089
Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsisQ77723439
Comparison of two polymorphisms of the interleukin-1 gene family: interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsisQ78124587
The genetics of inflammatory bowel diseaseQ78854425
Can NOD2/CARD15 mutations predict intestinal graft-versus-host disease and aid our understanding of Crohn's disease?Q81430999
Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontaminationQ82312167
P433issue9
P921main subjectpatientQ181600
sepsisQ183134
P304page(s)1541-1548
P577publication date2007-06-09
P1433published inIntensive Care MedicineQ15749164
P1476titleGenetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients
P478volume33

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