17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use

scientific article published on 09 July 2018

17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/ALL.13499
P932PMC publication ID6220986
P698PubMed publication ID29885281

P50authorMunir PirmohamedQ20127995
María Pino-YanesQ37375363
Hans BisgaardQ37615680
Maximilian SchieckQ37837856
Fook Tim ChewQ40364152
Klaus BønnelykkeQ41609532
Colin PalmerQ42603882
Erick FornoQ42701344
Daniel B. HawcuttQ47243710
Ben FrancisQ56581236
Patrícia SoaresQ56854245
Astrid SevelstedQ57334561
Katia VerhammeQ57338699
Esteban BurchardQ59752810
Steve TurnerQ62924969
Cilla SöderhällQ70673539
Michael KabeschQ87641081
Niloufar FarzanQ87920042
Susanne VijverbergQ89048879
Vojko BerceQ89048880
Juan Carlos CeledonQ89048881
Simon Kebede MeridQ89048882
Uros PotocnikQ89048883
Katja RepnikQ89048884
Rosalind SmythQ89048885
Sze Man TseQ89048887
A-H Maitland-van der ZeeQ89048888
Supratik MukhopadhyayQ102270406
P2093author name stringE Melén
R Tavendale
G Canino
M M Cloutier
W C Chiang
L Karimi
K G Tantisira
E H D Bel
E Herrera-Luis
N Hernandez-Pacheco
Y Y Sio
P2860cites workA polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medicationsQ28275529
A large-scale, consortium-based genomewide association study of asthmaQ28293885
Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European RespiraQ33691584
17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cellsQ37423775
Differences in asthma genetics between Chinese and other populations.Q38159835
Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortiumQ38668126
Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.Q41716771
Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.Q44053079
Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthmaQ58862200
P433issue10
P921main subjectasthmaQ35869
immunologyQ101929
P304page(s)2083-2088
P577publication date2018-07-09
P1433published inAllergyQ2699825
P1476title17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use
P478volume73

Reverse relations

cites work (P2860)
Q92963579Childhood asthma in the new omics era: challenges and perspectives
Q60913194Genetic associations of the response to inhaled corticosteroids in asthma: a systematic review
Q91633083Pharmacogenetics of Pediatric Asthma: Current Perspectives
Q92893745The Effects of the Environment on Asthma Disease Activity

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