A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB

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A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB is …
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P356DOI10.1038/NSMB1018
P698PubMed publication ID16299518

P50authorAndreas MatouschekQ4755537
P2093author name stringLin Tian
Robert A Holmgren
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Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a RepressorQ44894172
An unstructured initiation site is required for efficient proteasome-mediated degradationQ45018402
The degradation signal in a short-lived proteinQ45180905
Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway.Q46022608
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Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptusQ47070663
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein SlimbQ47070747
Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.Q47071799
Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.Q52178240
Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway.Q54071596
Protein Identification and Analysis Tools on the ExPASy ServerQ56880448
NF-κB p105 Processing via the Ubiquitin-Proteasome PathwayQ57024845
Systematic circular permutation of an entire protein reveals essential folding elementsQ73943512
P433issue12
P921main subjectNF-κBQ411114
P304page(s)1045-1053
P577publication date2005-11-20
P1433published inNature Structural & Molecular BiologyQ1071739
P1476titleA conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB
P478volume12