IL-12 overexpression in mice as a model for Sjögren lung disease

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IL-12 overexpression in mice as a model for Sjögren lung disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPLUNG.00134.2006
P698PubMed publication ID16751222

P50authorH KimuraQ54110008
Patrizio CaturegliQ88060055
P2093author name stringNoel R Rose
Shey-Cherng Tzou
Sharon McGrath-Morrow
Beth Laube
Cecilia Cho
Jeffrey Cleary
P2860cites workInterleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12Q24306559
Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cellsQ24675226
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory diseaseQ28202655
Transforming growth factor-beta regulation of immune responsesQ28303115
Natural killer cell activity in Sjögren's syndrome and systemic lupus erythematosus: stimulation with interferons and interleukin-2 and correlation with immune complexesQ33562953
Bronchial hyperresponsiveness to methacholine in patients with primary Sjögren's syndromeQ33563311
TGF-beta and fibrosisQ33804142
The pulmonary abnormalities in myxedemaQ34005209
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndromeQ34108411
Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus GroupQ34523084
Airway function and markers of airway inflammation in patients with treated hypothyroidismQ35537524
Lung involvement in primary Sjögren's syndrome is mainly related to the small airway diseaseQ35548191
Ten year follow up of pulmonary function in patients with primary Sjögren's syndromeQ35549609
TGF-beta, T-cell tolerance and anti-CD3 therapyQ35628232
Genetic basis of murine lupus.Q35661227
NK cells in innate immunityQ36010994
Close encounters of different kinds: dendritic cells and NK cells take centre stageQ36028182
Transforming growth factor beta (TGF-beta) and autoimmunityQ36246881
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytesQ36356764
Monocyte chemoattractant protein 1-dependent leukocytic infiltrates are responsible for autoimmune disease in MRL-Fas(lpr) miceQ36375621
Studies of the function of natural killer-interferon system in patients with Sjögren syndromeQ37008439
IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cellsQ39947194
Interleukin (IL)-12-driven primary hypothyroidism: the contrasting roles of two Th1 cytokines (IL-12 and interferon-gamma).Q40429349
Interleukin-12 therapy reduces the number of immune cells and pathology in lungs of mice infected with Mycobacterium tuberculosisQ40764004
Contact-dependent stimulation and inhibition of dendritic cells by natural killer cellsQ42005335
Elimination of both CD4+ and CD8+ T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient miceQ42253518
Turnover and proliferation of NK cells in steady state and lymphopenic conditionsQ44367388
IL-8 inhibits isoproterenol-stimulated ciliary beat frequency in bovine bronchial epithelial cellsQ45007120
Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene deliveryQ45875458
Augmented levels of macrophage and Th1 cell-related cytokine mRNA in submandibular glands of MRL/lpr mice with autoimmune sialoadenitis.Q47901611
Thin-section chest CT findings of primary Sjögren's syndrome: correlation with pulmonary function.Q51715065
Sjögren's syndromeQ55921808
P433issue4
P921main subjectlung diseaseQ3392853
overexpressionQ61643320
P304page(s)L837-46
P577publication date2006-06-02
P1433published inAmerican Journal of Physiology - Lung Cellular and Molecular PhysiologyQ4352992
P1476titleIL-12 overexpression in mice as a model for Sjögren lung disease
P478volume291

Reverse relations

cites work (P2860)
Q34428705A pilot study to examine the effect of chronic treatment with immunosuppressive drugs on mucociliary clearance in a vagotomized murine model
Q41361699Acute and chronic in vivo effects of exposure to nicotine and propylene glycol from an E-cigarette on mucociliary clearance in a murine model
Q38121787Advances in understanding the pathogenesis of primary Sjögren's syndrome
Q37613262Autoimmune thyroiditis: a model uniquely suited to probe regulatory T cell function.
Q41734803Increased incidence of Sjogren's syndrome in systemic sclerosis: A nationwide population study.
Q33767896Interleukin-12 induces salivary gland dysfunction in transgenic mice, providing a new model of Sjögren's syndrome.
Q38065960Interstitial lung diseases-can pathologists arrive at an etiology-based diagnosis? A critical update
Q34541173NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome
Q64917661Pulmonary Manifestations of Primary Sjögren's Syndrome: Underlying Immunological Mechanisms, Clinical Presentation, and Management.
Q41287188Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques
Q38116747Pulmonary manifestations of Sjögren's syndrome.
Q54544913Quantitative evaluation of interleukin-12 p40 gene expression in peripheral blood mononuclear cells.
Q36226075Sjögren syndrome: advances in the pathogenesis from animal models
Q35557789Sjögren's syndrome: studying the disease in mice
Q34033436Spontaneous autoimmune dacryoadenitis in aged CD25KO mice
Q38186111The value of animal models to study immunopathology of primary human Sjögren's syndrome symptoms.
Q37811063Transgenic modelling of cytokine polarization in the lung
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